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Masanori Hosokawa

Masanori Hosokawa

Kyoto University
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
10879
World Ranking
17530
National Ranking
1267

Masanori Hosokawa publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Masanori Hosokawa sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 184 publications — 43rd percentile

43% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Masanori Hosokawa D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Masanori Hosokawa sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 50 D-Index — 11th percentile

11% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Masanori Hosokawa is affiliated with Kyoto University in Japan and specializes in research intersecting Medicine and Computer Science. Their work predominantly focuses on Pharmacology, Computational Theory and Mathematics, and Molecular Biology, with additional contributions spanning Biomaterials and Cardiology and Cardiovascular Medicine.

Their research covers several main topics, including:

  • Computational Drug Discovery Methods
  • Cholinesterase and Neurodegenerative Diseases
  • Pharmacogenetics and Drug Metabolism
  • Muscle Physiology and Disorders
  • Silk-based biomaterials and applications
  • Cardiomyopathy and Myosin Studies
  • Zebrafish Biomedical Research Applications

Recent publications by Masanori Hosokawa and their collaborators demonstrate a focus on biochemical pharmacology and disease biomarkers. Key papers include:

  • "Effects of steric hindrance and electron density of ester prodrugs on controlling the metabolic activation by human carboxylesterase" (2021) published in Drug Metabolism and Pharmacokinetics
  • "Titin fragment is a sensitive biomarker in Duchenne muscular dystrophy model mice carrying full-length human dystrophin gene on human artificial chromosome" (2025) published in Scientific Reports
  • "Design, synthesis and biological evaluation of water-soluble phenytoin prodrugs considering the substrate recognition ability of human carboxylesterase 1" (2020) published in European Journal of Pharmaceutical Sciences
  • "The Zebrafish Cerebellar Neural Circuits Are Involved in Orienting Behavior" (2024) published in eNeuro
  • "Synthesis and evaluation of indomethacin prodrugs with a diester structure that are metabolically activated by human carboxylesterases" (2023) published in Xenobiotica

Frequent coauthors in Hosokawa's research include Masato Takahashi, Masami Haba, Daisuke Takani, Kohei Takahashi, and Ibuki Hirota, indicating collaboration across multiple studies involving drug metabolism and pharmacokinetics.

Publication venues commonly featuring Hosokawa's work are:

  • Drug Metabolism and Pharmacokinetics
  • Scientific Reports
  • eNeuro
  • European Journal of Pharmaceutical Sciences
  • Xenobiotica

The interdisciplinary nature of Hosokawa's work bridges computational methods and biomedical applications. This includes computational approaches to drug discovery alongside studies addressing enzyme activity related to human carboxylesterases and their role in drug metabolism and activation. Additionally, research extends to muscle physiology and neuromuscular disorders, including investigations into biomarkers for muscular dystrophy and neural circuits in zebrafish models, reflecting an integration of molecular biology and experimental neuroscience.

Best Publications

  • Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T1.

    Hironobu Naiki;Keiichi Higuchi;Masanori Hosokawa;Toshio Takeda

  • Senescence-accelerated-mouse (SAM) : a novel murine model of accelerated senescence

    Toshio Takeda;Masanori Hosokawa;Keiichi Higuchi

  • Senescence-accelerated mouse (SAM): a novel murine model of senescence.

    Toshio Takeda;Masanori Hosokawa;Keiichi Higuchi

  • Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis.

    Naoko Nagai;Masanori Hosokawa;Shigeyoshi Itohara;Eijiro Adachi

  • Grading score system: a method for evaluation of the degree of senescence in senescence accelerated mouse (SAM).

    Hosokawa M;Kasai R;Higuchi K;Takeshita S

  • Pathobiology of the senescence-accelerated mouse (SAM)

    Toshio Takeda;Takatoshi Matsushita;Mafumi Kurozumi;Kiminobu Takemura

  • SAMP8 mice as a neuropathological model of accelerated brain aging and dementia: Toshio Takeda's legacy and future directions.

    Ichiro Akiguchi;Ichiro Akiguchi;Mercè Pallàs;Herbert Budka;Haruhiko Akiyama

  • Spontaneous Spongy Degeneration of the Brain Stem in SAM-P/8 Mice, a Newly Developed Memory-Deficient Strain

    Hideo Yagi;Mika Irino;Takatoshi Matsushita;Seika Katoh

  • A higher oxidative status accelerates senescence and aggravates age-dependent disorders in SAMP strains of mice

    Masanori Hosokawa

  • Systemic senile amyloid in senescence-accelerated mice. A unique fibril protein demonstrated in tissues from various organs by the unlabeled immunoperoxidase method.

    Higuchi K;Matsumura A;Honma A;Takeshita S

  • Purification and characterization of a senile amyloid-related antigenic substance (apoSASSAM) from mouse serum. apoSASSAM is an apoA-II apolipoprotein of mouse high density lipoproteins.

    K Higuchi;T Yonezu;K Kogishi;A Matsumura

  • Secreted frizzled-related protein 4 is a negative regulator of peak BMD in SAMP6 mice

    Rika Nakanishi;Motoyuki Shimizu;Masayuki Mori;Haruhiko Akiyama

  • Polymorphism of apolipoprotein A-II (apoA-II) among inbred strains of mice. Relationship between the molecular type of apoA-II and mouse senile amyloidosis.

    K Higuchi;K Kitagawa;H Naiki;K Hanada

  • Identification of peak bone mass QTL in a spontaneously osteoporotic mouse strain.

    Motoyuki Shimizu;Keiichi Higuchi;Beth Bennett;Chen Xia

  • Dietary α-linolenate/linoleate balance influences learning and memory in the senescence-accelerated mouse (SAM)

    Makiko Umezawa;Akira Ohta;Hiromasa Tojo;Hideo Yagi

  • Neuropathological studies on strains of senescence-accelerated mice (SAM) with age-related deficits in learning and memory.

    Toshio Kawamata;Ichiro Akiguchi;Hideo Yagi;Mika Irino

  • Accelerated accumulation of somatic mutations in the senescence-accelerated mouse

    Youichi Odagiri;Hiroyuki Uchida;Masanori Hosokawa;Kazuo Takemoto

  • Risk of Fall for Individuals With Intellectual Disability

    Yoichi Chiba;Atsuyoshi Shimada;Futoshi Yoshida;Hiromi Keino

  • Age-related changes in the temporomandibular joint of the senescence accelerated mouse. SAM-P/3 as a new murine model of degenerative joint disease.

    W H Chen;M Hosokawa;T Tsuboyama;T Ono

  • Fluorometric Examination of Tissue Amyloid Fibrils in Murine Senile Amyloidosis: Use of the Fluorescent Indicator, Thioflavine T

    Hironobu Naiki;Keiichi Higuchi;Kaori Kitagawa;Atsuyoshi Shimada

Frequent Co-Authors

Keiichi Higuchi
Keiichi Higuchi Shinshu University
Toshio Takeda
Toshio Takeda Kyoto University
Hironobu Naiki
Hironobu Naiki University of Fukui
Takashi Nakamura
Takashi Nakamura Kyoto University
Jun Kimura
Jun Kimura University of Iowa
Rudolf K. Zahn
Rudolf K. Zahn Johannes Gutenberg University of Mainz
Tetsuya Hayashi
Tetsuya Hayashi Kyushu University
Yasuyuki Nomura
Yasuyuki Nomura Kurume University
Haruhiko Akiyama
Haruhiko Akiyama Gifu University
Kazuhiro Nagata
Kazuhiro Nagata Kyoto Sangyo University

External Links

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Best Scientists Citing Masanori Hosokawa

Keiichi Higuchi

Keiichi Higuchi

Shinshu University

Publications: 65

Vladimir N. Uversky

Vladimir N. Uversky

University of South Florida

Publications: 54

Mercè Pallàs

Mercè Pallàs

University of Barcelona

Publications: 44

Kazuhiro Nagata

Kazuhiro Nagata

Kyoto Sangyo University

Publications: 43

John E. Morley

John E. Morley

Saint Louis University

Publications: 42

Hironobu Naiki

Hironobu Naiki

University of Fukui

Publications: 40

Yuji Goto

Yuji Goto

Osaka University

Publications: 36

Anthony L. Fink

Anthony L. Fink

University of California, Santa Cruz

Publications: 34

Toshio Takeda

Toshio Takeda

Kyoto University

Publications: 32

Yasuyuki Nomura

Yasuyuki Nomura

Kurume University

Publications: 29

Antoni Camins

Antoni Camins

University of Barcelona

Publications: 23

Hans Peter Bächinger

Hans Peter Bächinger

Oregon Health & Science University

Publications: 20

Darío Acuña-Castroviejo

Darío Acuña-Castroviejo

University of Granada

Publications: 19

Per Westermark

Per Westermark

Uppsala University

Publications: 19

William A. Banks

William A. Banks

University of Washington

Publications: 16

Gunilla T. Westermark

Gunilla T. Westermark

Uppsala University

Publications: 16

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