Christian Frelin

Overview

Best Publications

• The sodium/hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH.

  Michel Lazdunski;Christian Frelin;Paul Vigne

  710
  Citations

• A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps).

  H Schweitz;P Vigne;D Moinier;C Frelin

  473
  Citations

• Hypoxia Is a Strong Inducer of Vascular Endothelial Growth Factor mRNA Expression in the Heart

  A. Ladoux;C. Frelin

  439
  Citations

• The regulation of the intracellular pH in cells from vertebrates.

  Christian Frelin;Paul Vigne;Annie Ladoux;Michel Lazdunski

  420
  Citations

• Molecular mechanism of action of the vasoconstrictor peptide endothelin.

  Catherine Van Renterghem;Paul Vigne;Jacques Barhanin;Annie Schmid-Alliana

  409
  Citations

• Hypoxia Up-regulates Prolyl Hydroxylase Activity A FEEDBACK MECHANSIM THAT LIMITS HIF-1 RESPONSES DURING REOXYGENATION

  Gisela D'Angelo;Eric Duplan;Nicole Boyer;Paul Vigne

  397
  Citations

• The P2Y1 Receptor Is Necessary for Adenosine 5′-Diphosphate–Induced Platelet Aggregation

  Béatrice Hechler;Catherine Léon;Catherine Léon;Catherine Vial;Catherine Vial;Paul Vigne;Paul Vigne

  370
  Citations

• Ciguatoxin is a novel type of Na+ channel toxin.

  J N Bidard;H P Vijverberg;C Frelin;E Chungue

  329
  Citations

• Structure-activity relationships of amiloride and certain of its analogues in relation to the blockade of the Na+/H+ exchange system.

  P Vigne;C Frelin;E J Cragoe;M Lazdunski

  292
  Citations

• The role of the Na+/H+ exchange system in cardiac cells in relation to the control of the internal Na+ concentration. A molecular basis for the antagonistic effect of ouabain and amiloride on the heart.

  C Frelin;P Vigne;M Lazdunski

  278
  Citations

• Ethylisopropyl-amiloride: a new and highly potent derivative of amiloride for the inhibition of the Na+/H+ exchange system in various cell types.

  Paul Vigne;Christian Frelin;Edward J. Cragoe;Michel Lazdunski

  225
  Citations

• Endothelin stimulates phosphatidylinositol hydrolysis and DNA synthesis in brain capillary endothelial cells.

  P Vigne;R Marsault;J P Breittmayer;C Frelin

  207
  Citations

• ATP derivatives are antagonists of the P2Y1 receptor: similarities to the platelet ADP receptor.

  Béatrice Hechler;Paul Vigne;Catherine Léon;Jean-Philippe Breittmayer

  205
  Citations

• Heart and lung VEGF mRNA expression in rats with monocrotaline- or hypoxia-induced pulmonary hypertension.

  Chohreh Partovian;Serge Adnot;Saadia Eddahibi;Emmanuel Teiger

  201
  Citations

• A new type of amiloride-sensitive cationic channel in endothelial cells of brain microvessels.

  P Vigne;G Champigny;R Marsault;P Barbry

  194
  Citations

• Purification and pharmacological properties of eight sea anemone toxins from Anemonia sulcata, Anthopleura xanthogrammica, Stoichactis giganteus, and Actinodendron plumosum.

  Hugues Schweitz;Jean Pierre Vincent;Jacques Barhanin;Christian Frelin

  193
  Citations

• Rapid transactivation of the vascular endothelial growth factor receptor KDR/Flk-1 by the bradykinin B2 receptor contributes to endothelial nitric-oxide synthase activation in cardiac capillary endothelial cells.

  Dominique Thuringer;Laurence Maulon;Christian Frelin

  167
  Citations

• The amiloride-sensitive Na+/H+ exchange system in skeletal muscle cells in culture.

  P Vigne;C Frelin;M Lazdunski

  162
  Citations

• The amiloride-sensitive Na+/H+ antiport in 3T3 fibroblasts.

  C Frelin;P Vigne;M Lazdunski

  162
  Citations

• Astrocytes Are Target Cells for Endothelins and Sarafotoxin

  Robert Marsault;Paul Vigne;Jean-Philippe Breittmayer;Christian Frelin

  162
  Citations