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Molecular Biology

D-Index
64
Citations
17963
World Ranking
1725
National Ranking
142

Overview

Izumu Saito is a researcher affiliated with the University of Tokyo in Japan, specializing in the fields of biochemistry, genetics, and molecular biology. Their work spans various subfields including molecular biology, genetics, epidemiology, hepatology, and ecology.

The primary focus of their research lies in CRISPR and genetic engineering, virus-based gene therapy, and RNA interference and gene delivery. They have also contributed to studies on Hepatitis B and C viruses, bacteriophages and microbial interactions, as well as viral infectious diseases and gene expression in insects.

The recent papers authored or co-authored by Izumu Saito include the following:

  • Construction of adenovirus vectors simultaneously expressing four multiplex, double-nicking guide RNAs of CRISPR/Cas9 and in vivo genome editing, 2021, Scientific Reports
  • Adenovirus Vectors Expressing Eight Multiplex Guide RNAs of CRISPR/Cas9 Efficiently Disrupted Diverse Hepatitis B Virus Gene Derived from Heterogeneous Patient, 2021, International Journal of Molecular Sciences
  • Acetophenone 4-nitrophenylhydrazone inhibits Hepatitis B virus replication by modulating capsid assembly, 2021, Virus Research
  • Construction and Stability of All-in-One Adenovirus Vectors Simultaneously Expressing Four and Eight Multiplex Guide RNAs and Cas9 Nickase, 2024, Preprints.org
  • Construction and Stability of All-in-One Adenovirus Vectors Simultaneously Expressing Four and Eight Multiplex Guide RNAs and Cas9 Nickase, 2024, International Journal of Molecular Sciences

Izumu Saito has frequently published in the following scientific venues:

  • International Journal of Molecular Sciences
  • Scientific Reports
  • Virus Research
  • Preprints.org

Their collaborative network includes regular co-authors such as Hirotaka Tabata, Tomoko Nakanishi, Mariko Nakamura, Yuya Kato, and Tomomi Nakahara, reflecting a consistent partnership in multiple research projects related to gene editing and viral vector development.

Best Publications

  • Hepatitis C virus infection is associated with the development of hepatocellular carcinoma

    I Saito;T Miyamura;A Ohbayashi;H Harada

  • HBx gene of hepatitis B virus induces liver cancer in transgenic mice

    Chang-Min Kim;Kazuhiko Koike;Izumu Saito;Tatsuo Miyamura

  • Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome.

    Sanae Miyake;Miho Makimura;Yumi Kanegae;Shizuko Harada

  • Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase.

    Y Kanegae;G Lee;Y Sato;M Tanaka

  • Rapid Colorectal Adenoma Formation Initiated by Conditional Targeting of the Apc Gene

    Hiroyuki Shibata;Kaoru Toyama;Hisashi Shioya;Masaki Ito

  • A SIMPLE AND EFFICIENT METHOD FOR PURIFICATION OF INFECTIOUS RECOMBINANT ADENOVIRUS

    Yumi Kanegae;Miho Makimura;Izumu Saito

  • Glia-synapse interaction through Ca2+-permeable AMPA receptors in Bergmann glia.

    Masae Iino;Kaori Goto;Wataru Kakegawa;Haruo Okado

  • Role of nucleotide sequences of loxP spacer region in Cre-mediated recombination

    Gwang Lee;Izumu Saito

  • Efficient gene transfer into various mammalian cells, including non-hepatic cells, by baculovirus vectors

    Ikuo Shoji;Hideki Aizaki;Hideki Tani;Koji Ishii

  • Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells.

    Ryouichi Horie;Takuro Watanabe;Yasuyuki Morishita;Kinji Ito

  • BabA-mediated Adherence Is a Potentiator of the Helicobacter pylori Type IV Secretion System Activity

    Nozomi Ishijima;Masato Suzuki;Hiroshi Ashida;Yusuke Ichikawa

  • The putative nucleocapsid and envelope protein genes of hepatitis C virus determined by comparison of the nucleotide sequences of two isolates derived from an experimentally infected chimpanzee and healthy human carriers.

    Kenji Takeuchi;Yoshihiro Kubo;Sumalee Boonmar;Yushiro Watanabe

  • Construction of nondefective adenovirus type 5 bearing a 2.8-kilobase hepatitis B virus DNA near the right end of its genome

    I Saito;Y Oya;K Yamamoto;T Yuasa

  • Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue.

    Masatoshi Haruta;Mitsuko Kosaka;Yumi Kanegae;Izumu Saito

  • Cell cycle arrest and apoptosis induced by Notch1 in B cells.

    Toshifumi Morimura;Ryo Goitsuka;Ryo Goitsuka;Yong Zhang;Izumu Saito

  • Expression of processed core protein of hepatitis C virus in mammalian cells.

    S Harada;Y Watanabe;K Takeuchi;T Suzuki

  • Nuclear localization of the truncated hepatitis C virus core protein with its hydrophobic C terminus deleted.

    Ryosuke Suzuki;Yoshiharu Matsuura;Tetsuro Suzuki;Ayako Ando

  • Detection of antibody against antigen expressed by molecularly cloned hepatitis C virus cDNA: application to diagnosis and blood screening for posttransfusion hepatitis.

    Tatsuo Miyamura;Izumu Saito;Tohru Katayama;Shu Kikuchi

  • A cDNA fragment of hepatitis C virus isolated from an implicated donor of post-transfusion non-A, non-B hepatitis in Japan

    Yoshihiro Kubo;Kenji Takeuchi;Sumalee Boonmar;Tohru Katayama

  • Serodiagnosis of hepatitis C virus (HCV) infection with an HCV core protein molecularly expressed by a recombinant baculovirus.

    Joe Chiba;Hiroyoshi Ohba;Yoshiharu Matsuura;Yushiro Watanabe

Frequent Co-Authors

Tatsuo Miyamura
Tatsuo Miyamura National Institutes of Health
Yoshiharu Matsuura
Yoshiharu Matsuura Osaka University
Tetsuro Suzuki
Tetsuro Suzuki Hamamatsu University
Hirofumi Hamada
Hirofumi Hamada Sapporo Medical University
Michael Houghton
Michael Houghton University of Alberta
George Kuo
George Kuo Novartis (United States)
Takahiro Ochiya
Takahiro Ochiya Tokyo Medical University
Masaaki Terada
Masaaki Terada National Cancer Research Institute, UK
Hideki Aizaki
Hideki Aizaki National Institutes of Health
Takaji Wakita
Takaji Wakita National Institute of Infectious Diseases

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