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Biology and Biochemistry
Netherlands
2023

D-Index & Metrics

Medicine

D-Index
103
Citations
60183
World Ranking
7183
National Ranking
272

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award

Overview

Alexandra Zhernakova is affiliated with the University Medical Center Groningen in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in subfields such as Molecular Biology, Genetics, Public Health, Environmental and Occupational Health, Epidemiology, and Physiology.

Their work centers on various topics including gut microbiota and health, diet and metabolism studies, nutritional studies and diet, epigenetics and DNA methylation, metabolomics and mass spectrometry studies, bacteriophages and microbial interactions, as well as research on Clostridium difficile and Clostridium perfringens.

Their recent publications include:

  • "Interaction between drugs and the gut microbiome" (2020, Gut)
  • "Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals" (2020, Nature Metabolism)
  • "Impact of commonly used drugs on the composition and metabolic function of the gut microbiota" (2020, Nature Communications)
  • "Environmental factors shaping the gut microbiome in a Dutch population" (2022, Nature)
  • "Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome" (2021, Gut)

They have collaborated frequently with researchers such as Jingyuan Fu, Alexander Kurilshikov, Cisca Wijmenga, Rinse K. Weersma, and Ranko Gaćeša.

Key publication venues where Alexandra Zhernakova has contributed include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Research Square, Gut, and Cell Reports.

Alexandra Zhernakova has also contributed to book literature, notably through a publication with University of Groningen Press titled "The Gut Microbiome: A universe inside us" released in 2023.

Best Publications

  • Environment dominates over host genetics in shaping human gut microbiota

    Daphna Rothschild;Omer Weissbrod;Elad Barkan;Alexander Kurilshikov

  • Genetics of rheumatoid arthritis contributes to biology and drug discovery

    Yukinori Okada;Yukinori Okada;Di Wu;Di Wu;Di Wu;Gosia Trynka;Gosia Trynka;Towfique Raj;Towfique Raj

  • Population-level analysis of gut microbiome variation

    Gwen Falony;Marie Joossens;Marie Joossens;Sara Vieira-Silva;Jun Wang

  • Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity.

    Alexandra Zhernakova;Alexander Kurilshikov;Marc Jan Bonder;Ettje F. Tigchelaar

  • Systematic identification of trans eQTLs as putative drivers of known disease associations

    Harm-Jan Westra;Marjolein J Peters;Tõnu Esko;Hanieh Yaghootkar

  • The neuroactive potential of the human gut microbiota in quality of life and depression

    Mireia Valles-Colomer;Mireia Valles-Colomer;Gwen Falony;Gwen Falony;Youssef Darzi;Youssef Darzi;Ettje F Tigchelaar

  • Gut microbiome structure and metabolic activity in inflammatory bowel disease

    Eric A Franzosa;Eric A Franzosa;Alexandra Sirota-Madi;Julian Avila-Pacheco;Nadine Fornelos

  • Large-scale association analyses identify host factors influencing human gut microbiome composition

    Alexander Kurilshikov;Carolina Medina-Gomez;Rodrigo Bacigalupe;Djawad Radjabzadeh

  • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

    Eli A Stahl;Soumya Raychaudhuri;Soumya Raychaudhuri;Elaine F Remmers;Gang Xie

  • Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases.

    Serena Sanna;Natalie R van Zuydam;Natalie R van Zuydam;Anubha Mahajan;Alexander Kurilshikov

  • Proton pump inhibitors affect the gut microbiome

    Floris Imhann;Marc Jan Bonder;Arnau Vich Vila;Jingyuan Fu

  • Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity.

    Melanie Schirmer;Melanie Schirmer;Sanne P. Smeekens;Hera Vlamakis;Martin Jaeger

  • Multiple common variants for celiac disease influencing immune gene expression

    Patrick C. A. Dubois;Gosia Trynka;Lude Franke;Lude Franke;Karen A. Hunt

  • Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

    Gosia Trynka;Karen A Hunt;Nicholas A Bockett;Jihane Romanos

  • The effect of host genetics on the gut microbiome

    Marc Jan Bonder;Alexander Kurilshikov;Alexander Kurilshikov;Ettje F Tigchelaar;Zlatan Mujagic

  • Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

    Simone Wahl;Alexander Drong;Benjamin Lehne;Marie Loh;Marie Loh;Marie Loh

  • Newly identified genetic risk variants for celiac disease related to the immune response

    Karen A Hunt;Alexandra Zhernakova;Graham Turner;Graham A R Heap

  • A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

    David A. van Heel;Lude Franke;Karen A. Hunt;Rhian Gwilliam

  • High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

    Steve Eyre;John Bowes;John Bowes;Dorothée Diogo;Dorothée Diogo;Annette Lee

  • Proton pump inhibitors affect the gut microbiome

    F. Imhann;M. J. Bonder;A. Vich Vila;J. Fu

Frequent Co-Authors

Cisca Wijmenga
Cisca Wijmenga University Medical Center Groningen
Jingyuan Fu
Jingyuan Fu University Medical Center Groningen
Lude Franke
Lude Franke University Medical Center Groningen
Alexander Kurilshikov
Alexander Kurilshikov University of Groningen
Rinse K. Weersma
Rinse K. Weersma University Medical Center Groningen
Marc Jan Bonder
Marc Jan Bonder University of Groningen
Mihai G. Netea
Mihai G. Netea Radboud University
Gosia Trynka
Gosia Trynka Wellcome Sanger Institute
Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Patrick Deelen
Patrick Deelen University Medical Center Groningen

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