D-Index & Metrics Best Publications

Michaela U. Gack

Cleveland Clinic
United States

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Biology and Biochemistry D-index 41 Citations 18,609 80 World Ranking 17367 National Ranking 7117

Overview

What is she best known for?

The fields of study Michaela U. Gack is best known for:

Gene
Virus
Immune system

Research on DNA virus and Pseudogene is a part of her Genome study. In her works, she performs multidisciplinary study on Pseudogene and Gene. She conducted interdisciplinary study in her works that combined Gene and Herpes simplex virus. In her articles, she combines various disciplines, including Herpes simplex virus and Virus. Michaela U. Gack undertakes multidisciplinary studies into Virus and Influenza A virus in her work. As part of her studies on Influenza A virus, she often connects relevant subjects like Virology. She performs integrative Virology and Molecular biology research in her work. Michaela U. Gack merges Molecular biology with Genome in her research. Her Genetics study frequently links to adjacent areas such as DNA virus.

Her most cited work include:

RIG-I-like receptors: their regulation and roles in RNA sensing (567 citations)
Dysregulation of type I interferon responses in COVID-19 (321 citations)
Viral evasion of intracellular DNA and RNA sensing (311 citations)

What are the main themes of her work throughout her whole career to date

Borrowing concepts from Computational biology, Michaela U. Gack weaves in ideas under Genetics. She integrates many fields in her works, including Computational biology and Genetics. Her Virology study often links to related topics such as Flavivirus. She integrates many fields in her works, including Flavivirus and Virus. She performs integrative study on Virus and Dengue virus. The study of Dengue virus is intertwined with the study of Virology in a number of ways. In her study, she carries out multidisciplinary Gene and Ubiquitin research. Michaela U. Gack integrates Ubiquitin with Gene in her study. Michaela U. Gack regularly ties together related areas like Signal transduction in her Cell biology studies.

Michaela U. Gack most often published in these fields:

Genetics (74.07%)
Virology (70.37%)
Gene (70.37%)

What were the highlights of her more recent work (between 2020-2023)?

Gene (100.00%)
Genetics (100.00%)
Virology (66.67%)

In recent works Michaela U. Gack was focusing on the following fields of study:

While working in this field, Michaela U. Gack studies both Gene and Recombinant DNA. She incorporates Recombinant DNA and Virus in her studies. Her work often combines Virus and Virulence studies. As part of her studies on Genetics, she frequently links adjacent subjects like Autophagy. By researching both Virology and Interferon, Michaela U. Gack produces research that crosses academic boundaries. Michaela U. Gack performs multidisciplinary study on Interferon and Virology in her works. Her Cell biology study frequently involves adjacent topics like Actin. Her research links Cell biology with Actin. Michaela U. Gack combines Phenotype and Gene in her research.

Between 2020 and 2023, her most popular works were:

The antiviral activities of TRIM proteins (36 citations)
Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation (12 citations)
Actin cytoskeleton remodeling primes RIG-I-like receptor activation (6 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif.
Autophagy (2021)

8964 Citations

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

Michaela U. Gack;Young C. Shin;Chul Hyun Joo;Chul Hyun Joo;Tomohiko Urano;Tomohiko Urano.
Nature (2007)

1643 Citations

Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

Michaela Ulrike Gack;Randy Allen Albrecht;Tomohiko Urano;Tomohiko Urano;Kyung-Soo Inn;Kyung-Soo Inn.
Cell Host & Microbe (2009)

900 Citations

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

Chengyu Liang;Chengyu Liang;Jong-soo Lee;Jong-soo Lee;Kyung-Soo Inn;Kyung-Soo Inn;Michaela U. Gack;Michaela U. Gack.
Nature Cell Biology (2008)

842 Citations

RIG-I-like receptors: their regulation and roles in RNA sensing

Jan Rehwinkel;Michaela U. Gack.
Nature Reviews Immunology (2020)

450 Citations

Cytosolic Viral Sensor RIG-I Is a 5′-Triphosphate-Dependent Translocase on Double-Stranded RNA

Su-A Myong;Sheng Cui;Peter V. Cornish;Peter V. Cornish;Axel Kirchhofer.
Science (2009)

407 Citations

Viral evasion of intracellular DNA and RNA sensing

Ying Kai Chan;Michaela U. Gack.
Nature Reviews Microbiology (2016)

372 Citations

Dysregulation of type I interferon responses in COVID-19.

Dhiraj Acharya;Guan Qun Liu;Michaela U. Gack.
Nature Reviews Immunology (2020)

314 Citations

Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein

Ricardo Rajsbaum;Randy A. Albrecht;May K. Wang;Natalya P. Maharaj.
PLOS Pathogens (2012)

306 Citations

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling

Effi Wies;May K. Wang;Natalya P. Maharaj;Kan Chen.
Immunity (2013)

292 Citations

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Frequent Co-Authors

External Links

Personal Website for Michaela U. Gack