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Michaela U. Gack

Michaela U. Gack

Cleveland Clinic
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
25239
World Ranking
17808
National Ranking
7288

Michaela U. Gack publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Michaela U. Gack sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 111 publications — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Michaela U. Gack D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Michaela U. Gack sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 49 D-Index — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Michaela U. Gack is affiliated with the Cleveland Clinic in the United States and has a research portfolio centered on medicine, immunology, microbiology, and molecular biology. Their work primarily spans infectious diseases and immunology, with significant contributions to the study of interferon and immune responses, SARS-CoV-2 and COVID-19 research, and the investigation of immune disorders.

The scientist's research topics include:

  • Interferon and immune responses
  • SARS-CoV-2 and COVID-19 research
  • COVID-19 clinical research studies
  • Inflammasome and immune disorders
  • Immune response and inflammation
  • Viral infections and vectors
  • Cytomegalovirus and herpesvirus research

Gack has authored multiple research articles published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Proceedings of the National Academy of Sciences, Nature Reviews Immunology, and PLoS Biology. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Nature reviews. Immunology
  • PLoS Biology

Recent significant papers by Michaela U. Gack include:

  • "RIG-I-like receptors: their regulation and roles in RNA sensing," 2020, Nature reviews. Immunology
  • "Dysregulation of type I interferon responses in COVID-19," 2020, Nature reviews. Immunology
  • "ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity," 2021, Nature Microbiology
  • "A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19," 2020, PLoS Biology
  • "Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2," 2021, PLoS Pathogens

Gack frequently collaborates with other researchers in their field. Notable co-authors include Guanqun Liu, Dhiraj Acharya, Junji Zhu, Zuberwasim Sayyad, and Cindy Chiang.

The scientist's extensive contributions mainly cover the subfields of infectious diseases, immunology, molecular biology, epidemiology, and oncology, with a focus on understanding host-pathogen interactions and immune system mechanisms related to viral infections and inflammatory processes.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

    Michaela U. Gack;Young C. Shin;Chul Hyun Joo;Chul Hyun Joo;Tomohiko Urano;Tomohiko Urano

  • RIG-I-like receptors: their regulation and roles in RNA sensing

    Jan Rehwinkel;Michaela U. Gack

  • Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

    Michaela Ulrike Gack;Randy Allen Albrecht;Tomohiko Urano;Tomohiko Urano;Kyung-Soo Inn;Kyung-Soo Inn

  • Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

    Chengyu Liang;Chengyu Liang;Jong-soo Lee;Jong-soo Lee;Kyung-Soo Inn;Kyung-Soo Inn;Michaela U. Gack;Michaela U. Gack

  • Cytosolic Viral Sensor RIG-I Is a 5′-Triphosphate-Dependent Translocase on Double-Stranded RNA

    Su-A Myong;Sheng Cui;Peter V. Cornish;Peter V. Cornish;Axel Kirchhofer

  • Viral evasion of intracellular DNA and RNA sensing

    Ying Kai Chan;Michaela U. Gack

  • Dysregulation of type I interferon responses in COVID-19.

    Dhiraj Acharya;Guan Qun Liu;Michaela U. Gack

  • Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein

    Ricardo Rajsbaum;Randy A. Albrecht;May K. Wang;Natalya P. Maharaj

  • Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling

    Effi Wies;May K. Wang;Natalya P. Maharaj;Kan Chen

  • Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

    Michaela U. Gack;Axel Kirchhofer;Young C. Shin;Kyung Soo Inn;Kyung Soo Inn

  • TRIM Proteins and Their Roles in Antiviral Host Defenses

    Michiel van Gent;Konstantin M.J. Sparrer;Michaela U. Gack

  • ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity.

    GuanQun Liu;GuanQun Liu;Jung-Hyun Lee;Jung-Hyun Lee;Zachary M. Parker;Dhiraj Acharya;Dhiraj Acharya

  • Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.

    Jessica J Chiang;Konstantin M J Sparrer;Michiel van Gent;Charlotte Lässig

  • Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction

    Kyung-Soo Inn;Michaela U. Gack;Michaela U. Gack;Fuminori Tokunaga;Mude Shi

  • TRIM23 mediates virus-induced autophagy via activation of TBK1

    Konstantin M. J. Sparrer;Sebastian Gableske;Matthew A. Zurenski;Zachary M. Parker

  • RIG-I-like receptor regulation in virus infection and immunity.

    Ying Kai Chan;Michaela U Gack

  • Ubiquitination in the antiviral immune response

    Meredith E. Davis;Michaela U. Gack

  • Post-translational Control of Intracellular Pathogen Sensing Pathways

    Cindy Chiang;Michaela U. Gack

  • Inhibition of Interferon Regulatory Factor 7 (IRF7)-Mediated Interferon Signal Transduction by the Kaposi's Sarcoma-Associated Herpesvirus Viral IRF Homolog vIRF3

    Chul Hyun Joo;Young C. Shin;Michaela Gack;Liguo Wu

Frequent Co-Authors

Jae U. Jung
Jae U. Jung Cleveland Clinic
Feixiong Cheng
Feixiong Cheng Case Western Reserve University
Lara Jehi
Lara Jehi Cleveland Clinic
Nicos A. Nicola
Nicos A. Nicola Walter and Eliza Hall Institute of Medical Research
Jeffrey J. Babon
Jeffrey J. Babon Walter and Eliza Hall Institute of Medical Research
Sandra E. Nicholson
Sandra E. Nicholson Walter and Eliza Hall Institute of Medical Research
Karl-Peter Hopfner
Karl-Peter Hopfner Ludwig-Maximilians-Universität München
Satoshi Inoue
Satoshi Inoue Saitama Medical University
Adolfo García-Sastre
Adolfo García-Sastre Icahn School of Medicine at Mount Sinai
Charis Eng
Charis Eng Cleveland Clinic Lerner College of Medicine

External Links

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Related Online Degrees & Career Pathways

Pursuing a degree in Biology or Biochemistry in the USA opens doors to many related healthcare and science career pathways. Online education now makes it easier than ever to access these opportunities, often with flexible scheduling and lower tuition costs.

For students interested in medical imaging, there are online rad tech programs that provide a practical entry point into radiologic technology careers. Those drawn to nutrition and public health may consider the best dietetics programs available online, many of which equip graduates to become registered dietitians.

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These degree and certificate options complement a background in Biology or Biochemistry, allowing for diverse roles in healthcare, research, and allied fields.

Best Scientists Citing Michaela U. Gack

Adolfo García-Sastre

Adolfo García-Sastre

Icahn School of Medicine at Mount Sinai

Publications: 72

Jae U. Jung

Jae U. Jung

Cleveland Clinic

Publications: 47

Xuetao Cao

Xuetao Cao

Chinese Academy of Medical Sciences & Peking Union Medical College

Publications: 43

Michael Gale

Michael Gale

University of Washington

Publications: 33

Hiroyuki Oshiumi

Hiroyuki Oshiumi

Kumamoto University

Publications: 32

Shizuo Akira

Shizuo Akira

Osaka University

Publications: 29

Takashi Fujita

Takashi Fujita

Kyoto University

Publications: 28

Taekjip Ha

Taekjip Ha

Johns Hopkins University

Publications: 26

Anna Marie Pyle

Anna Marie Pyle

Yale University

Publications: 25

Zhijian J. Chen

Zhijian J. Chen

The University of Texas Southwestern Medical Center

Publications: 23

Tsukasa Seya

Tsukasa Seya

Hokkaido University

Publications: 23

Hong-Bing Shu

Hong-Bing Shu

Wuhan University

Publications: 21

Sua Myong

Sua Myong

Johns Hopkins University

Publications: 20

Guido Kroemer

Guido Kroemer

Université Paris Cité

Publications: 19

John Hiscott

John Hiscott

Istituto Pasteur

Publications: 19

Mitsutoshi Yoneyama

Mitsutoshi Yoneyama

Chiba University

Publications: 18

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