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Neuroscience

D-Index
53
Citations
11152
World Ranking
5073
National Ranking
212

Overview

Wim E. Crusio is affiliated with the University of Bordeaux in France. Their research spans multiple interconnected areas within biomedicine, with a focus on genetics, neuroscience, and medicine. The scientist's work engages deeply with neurodevelopmental and neurodegenerative disorders, reflecting a broad interest in understanding complex biological mechanisms and their implications for human health.

Their main fields of study include medicine, biochemistry, genetics and molecular biology, and neuroscience. Within these broader categories, Crusio has focused on specific subfields such as cognitive neuroscience, molecular biology, genetics, epidemiology, and neurology.

Key topics covered in their research are:

  • Genetics and neurodevelopmental disorders
  • Autism spectrum disorder research
  • Parkinson's disease mechanisms and treatments
  • Sleep and wakefulness research
  • Epigenetics and DNA methylation
  • Down syndrome and intellectual disability research
  • Alzheimer's disease research and treatments

Their recent publications demonstrate activity across several important scientific venues, including:

  • Behavioral and Brain Functions (2020): "Behavioral and Brain Functions at 15"
  • Autism Research (2021): "Communication and social interaction in the cannabinoid-type 1 receptor null mouse: Implications for autism spectrum disorder"
  • Scientific Reports (2022): "Autistic-like behavioral effects of prenatal stress in juvenile Fmr1 mice: the relevance of sex differences and gene-environment interactions"
  • F1000Research (2020 and 2021): "Common genetic signatures of Alzheimer's disease in Down Syndrome"

Crusio has collaborated frequently with several coauthors, including Susanna Pietropaolo, Alisha Chunduri, Anna Delprato, Heinfried H. Radeke, and Marika Premoli. These collaborations underline a multidisciplinary approach to research.

Regarding book publications, Crusio has contributed to multiple works published by Springer Nature. These include titles focused on neuroscience and biomedical applications such as:

  • Frontotemporal Dementias (2021)
  • Multifaceted Biomedical Applications of Graphene (2022)
  • Nanotoxicology in Safety Assessment of Nanomaterials (2022)
  • Innate Lymphoid Cells (2022)
  • Coronavirus Therapeutics - Volume II (2021)

Best Publications

  • The Collaborative Cross, a community resource for the genetic analysis of complex traits

    Gary A. Churchill;David C. Airey;Hooman Allayee;Joe M. Angel

  • Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse

    Frederick Albert Schroeder;Cong L. Lin;Wim E. Crusio;Schahram Akbarian

  • The nature and identification of quantitative trait loci: a community's view.

    Oduola Abiola;Joe M. Angel;Philip Avner;Alexander A. Bachmanov

  • Effects of unpredictable chronic mild stress on anxiety and depression-like behavior in mice.

    Yann S. Mineur;Catherine Belzung;Wim E. Crusio

  • Knockout mice: simple solutions to the problems of genetic background and flanking genes

    David P Wolfer;Wim E Crusio;Hans Peter Lipp

  • Radial-maze performance and structural variation of the hippocampus in mice: a correlation with mossy fibre distribution.

    Wim E. Crusio;Herbert Schwegler;Hans-Peter Lipp

  • Behavioral and neuroanatomical characterization of the Fmr1 knockout mouse.

    Yann S. Mineur;Yann S. Mineur;Frans Sluyter;Sanne de Wit;Ben A. Oostra

  • 13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice

    James E. Crandall;Yasuo Sakai;Jinhua Zhang;Omanand Koul

  • Genetic dissection of mouse exploratory behaviour

    Wim E Crusio

  • Hippocampal mossy fibers and radial-maze learning in the mouse: a correlation with spatial working memory but not with non-spatial reference memory.

    H. Schwegler;W.E. Crusio;I. Brust

  • Reproducibility and replicability of rodent phenotyping in preclinical studies.

    Neri Kafkafi;Joseph Agassi;Elissa J. Chesler;John C. Crabbe

  • Genetic-Background Modulation of Core and Variable Autistic-Like Symptoms in Fmr1 Knock-Out Mice

    Susanna Pietropaolo;Aurélie Guilleminot;Aurélie Guilleminot;Benoît Martin;Benoît Martin;Francesca R. D'Amato

  • Fmr1 KO Mice as a Possible Model of Autistic Features

    Maude Bernardet;Wim E. Crusio

  • Social behavior deficits in the Fmr1 mutant mouse.

    Yann S. Mineur;Linh X. Huynh;Wim E. Crusio

  • Agonistic behavior and unpredictable chronic mild stress in mice.

    Yann S. Mineur;Daniel J. Prasol;Catherine Belzung;Wim E. Crusio

  • Functional implications of decreases in neurogenesis following chronic mild stress in mice

    Y.S. Mineur;C. Belzung;W.E. Crusio

  • Flanking gene and genetic background problems in genetically manipulated mice.

    Wim E. Crusio

  • Behavioral responses to novelty and structural variation of the hippocampus in mice. II. Multivariate genetic analysis

    W.E. Crusio;H. Schwegler;J.H.F. van Abeelen

  • Standards for the publication of mouse mutant studies.

    W. E. Crusio;D. Goldowitz;A. Holmes;D. Wolfer;D. Wolfer

  • AN INTRODUCTION TO QUANTITATIVE GENETICS

    WIm E. Crusio

  • What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice

    Wim E. Crusio

Frequent Co-Authors

Yann S. Mineur
Yann S. Mineur Yale University
Herbert Schwegler
Herbert Schwegler Otto-von-Guericke University Magdeburg
Robert Gerlai
Robert Gerlai University of Toronto
Robert W. Williams
Robert W. Williams University of Tennessee Health Science Center
Elissa J. Chesler
Elissa J. Chesler University of Tennessee at Knoxville
Leonard C. Schalkwyk
Leonard C. Schalkwyk University of Essex
Hans-Peter Lipp
Hans-Peter Lipp University of Zurich
Francesca R. D'Amato
Francesca R. D'Amato National Research Council (CNR)
Lu Lu
Lu Lu University of Tennessee Health Science Center
David P. Wolfer
David P. Wolfer University of Zurich

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