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Immunology

D-Index
81
Citations
26714
World Ranking
1551
National Ranking
60

Medicine

D-Index
81
Citations
26750
World Ranking
16540
National Ranking
539

Overview

Pierre Lebon is affiliated with Université Paris Cité in France and has contributed to the field of medicine with a focus on several specialized areas. Their research spans subfields such as surgery, molecular biology, infectious diseases, epidemiology, and immunology.

Their work covers topics including Kawasaki disease and coronary complications, SARS-CoV-2 and COVID-19 research, cardiac structural anomalies and repair, virology and viral diseases, systemic lupus erythematosus research, interferon and immune responses, and cytokine signaling pathways and interactions.

Lebon has authored publications in multiple venues, notably Revue Neurologique, New England Journal of Medicine, Science, The Journal of Experimental Medicine, and The Lancet Neurology. Key recent papers include:

  • Measles Sclerosing Subacute PanEncephalitis (SSPE), an intriguing and ever-present disease: Data, assumptions and new perspectives, 2021, Revue Neurologique
  • Janus Kinase Inhibition in the Aicardi-Goutières Syndrome, 2020, New England Journal of Medicine
  • Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children, 2022, Science
  • SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?, 2021, The Journal of Experimental Medicine
  • Autoinflammatory encephalopathy due to PTPN1 haploinsufficiency: a case series, 2025, The Lancet Neurology

Frequent collaborators in their research have included A. Gélot, Jean-Laurent Casanova, Danyel Lee, Peng Zhang, and Iolanda Jordán. The publication record indicates repeated collaboration with these coauthors across various projects.

Lebon's areas of publication concentrate chiefly on topics at the intersection of immunology and infectious diseases, with a strong orientation towards understanding complex viral conditions and immune system dysregulation. This research focus is reflected both in their choice of topics and the selection of high-impact scientific journals for dissemination.

Best Publications

  • TLR3 deficiency in patients with herpes simplex encephalitis.

    Shen Ying Zhang;Shen Ying Zhang;Emmanuelle Jouanguy;Emmanuelle Jouanguy;Sophie Ugolini;Asma Smahi

  • Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

    Gillian I. Rice;Paul R. Kasher;Gabriella M A Forte;Niamh M. Mannion

  • Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus.

    Yanick J Crow;Yanick J Crow;Bruce E Hayward;Rekha Parmar;Peter Robins

  • Herpes simplex virus encephalitis in human UNC-93B deficiency.

    Armanda Casrouge;Shen Ying Zhang;Shen Ying Zhang;Céline Eidenschenk;Emmanuelle Jouanguy;Emmanuelle Jouanguy

  • Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response.

    Gillian I Rice;Jacquelyn Bond;Aruna Asipu;Rebecca L Brunette

  • Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection.

    Yanick J Crow;Yanick J Crow;Andrea Leitch;Bruce E Hayward;Anna Garner

  • Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages

    Karine Labadie;Thibaut Larcher;Christophe Joubert;Abdelkrim Mannioui

  • Outcome of and Prognostic Factors for Herpes Simplex Encephalitis in Adult Patients: Results of a Multicenter Study

    Franck Raschilas;Michel Wolff;Frédérique Delatour;Cendrine Chaffaut

  • Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1.

    Yanick J. Crow;Diana S. Chase;Johanna Lowenstein Schmidt;Marcin Szynkiewicz

  • Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

    Gillian I Rice;Yoandris del Toro Duany;Yoandris del Toro Duany;Emma M Jenkinson;Gabriella M A Forte

  • Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

    Xianqin Zhang;Dusan Bogunovic;Béatrice Payelle-Brogard;Véronique Francois-Newton

  • Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

    Béatrice Jacquelin;Véronique Mayau;Brice Targat;Anne Sophie Liovat

  • Clinical and Molecular Phenotype of Aicardi-Goutières Syndrome

    Gillian Rice;Teresa Patrick;Rekha Parmar;Claire F Taylor

  • Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study

    Gillian I Rice;Gabriella M A Gm Forte;Marcin Szynkiewicz;Diana S Chase

  • Measurement of Procalcitonin Levels in Children with Bacterial or Viral Meningitis

    Dominique Gendrel;Josette Raymond;Marcel Assicot;Florence Moulin

  • Reduced blood CD123 + (lymphoid) and CD11c + (myeloid) dendritic cell numbers in primary HIV-1 infection

    Jérôme Pacanowski;Sandrine Kahi;Marjorie Baillet;Pierre Lebon

  • Human TRAF3 Adaptor Molecule Deficiency Leads to Impaired Toll-like Receptor 3 Response and Susceptibility to Herpes Simplex Encephalitis

    Rebeca Pérez de Diego;Rebeca Pérez de Diego;Rebeca Pérez de Diego;Vanessa Sancho-Shimizu;Vanessa Sancho-Shimizu;Vanessa Sancho-Shimizu;Lazaro Lorenzo;Lazaro Lorenzo;Lazaro Lorenzo;Anne Puel;Anne Puel;Anne Puel

  • Coronavirus 229E-related pneumonia in immunocompromised patients.

    Frédéric Pene;Annabelle Merlat;Astrid Vabret;Flore Rozenberg

  • Human TLR-7-, -8-, and -9-Mediated Induction of IFN-α/β and -λ Is IRAK-4 Dependent and Redundant for Protective Immunity to Viruses

    Kun Yang;Kun Yang;Anne Puel;Shenying Zhang;Shenying Zhang;Céline Eidenschenk

  • Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood

    Melina Herman;Michael Ciancanelli;Yi Hung Ou;Lazaro Lorenzo

Frequent Co-Authors

Flore Rozenberg
Flore Rozenberg Université Paris Cité
Yanick J. Crow
Yanick J. Crow Université Paris Cité
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Emmanuelle Jouanguy
Emmanuelle Jouanguy Necker-Enfants Malades Hospital
Gillian I. Rice
Gillian I. Rice University of Manchester
Laurent Abel
Laurent Abel Université Paris Cité
Shen-Ying Zhang
Shen-Ying Zhang Rockefeller University
Michael G. Tovey
Michael G. Tovey École Normale Supérieure Paris-Saclay
Anne Hosmalin
Anne Hosmalin Institut Pasteur
Capucine Picard
Capucine Picard Université Paris Cité

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Related Online Degrees & Career Pathways

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