What is he best known for?
The fields of study he is best known for:
- Virus
- Gene
- Internal medicine
His primary areas of study are Immunology, Virology, Aicardi–Goutières syndrome, Interferon type I and Interferon.
Many of his studies on Immunology apply to Disease as well.
His studies examine the connections between Virology and genetics, as well as such issues in Phenotype, with regards to Heterozygote advantage, Kinase activity, Dominance and Allele.
His work deals with themes such as Biomarker, Aicardi syndrome, Encephalopathy and Autoantibody, which intersect with Aicardi–Goutières syndrome.
The concepts of his Interferon study are interwoven with issues in Tumor necrosis factor alpha, Receptor, TRAF3, TNF Receptor-Associated Factor 3 and TLR3.
The Mutation research Pierre Lebon does as part of his general Genetics study is frequently linked to other disciplines of science, such as Ribonucleotide excision repair, therefore creating a link between diverse domains of science.
His most cited work include:
- TLR3 deficiency in patients with herpes simplex encephalitis. (839 citations)
- Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus. (605 citations)
- Herpes simplex virus encephalitis in human UNC-93B deficiency. (579 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Immunology, Virology, Interferon, Virus and Alpha interferon.
His research on Immunology frequently links to adjacent areas such as Aicardi–Goutières syndrome.
The Aicardi–Goutières syndrome study which covers Pathology that intersects with Pregnancy.
His Virology research incorporates elements of Peripheral blood mononuclear cell and Antibody.
His Virus research incorporates themes from Human bocavirus, Measles virus and Microbiology.
He interconnects Fetus and Amniotic fluid in the investigation of issues within Alpha interferon.
He most often published in these fields:
- Immunology (51.24%)
- Virology (35.82%)
- Interferon (19.90%)
What were the highlights of his more recent work (between 2008-2020)?
- Immunology (51.24%)
- Interferon (19.90%)
- Virology (35.82%)
In recent papers he was focusing on the following fields of study:
Pierre Lebon focuses on Immunology, Interferon, Virology, Immune system and Aicardi–Goutières syndrome.
His work carried out in the field of Immunology brings together such families of science as Internal medicine and Disease.
His Interferon research focuses on Peripheral blood mononuclear cell and how it relates to Herpes simplex virus.
Pierre Lebon combines subjects such as Inflammation, Phenotype, Antibody and Immunity with his study of Virology.
His Immune system research includes themes of Tumor necrosis factor alpha, Cancer research and Downregulation and upregulation.
His research in Aicardi–Goutières syndrome intersects with topics in Autoantibody, Aicardi syndrome, Encephalopathy and Pathology.
Between 2008 and 2020, his most popular works were:
- Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response. (502 citations)
- Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature (459 citations)
- Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response (403 citations)
In his most recent research, the most cited papers focused on:
- Virus
- Gene
- Internal medicine
His main research concerns Immunology, Interferon, Interferon type I, Aicardi–Goutières syndrome and Immune system.
His studies deal with areas such as Disease and Virology as well as Immunology.
The study incorporates disciplines such as Phenotype and Pathogenesis in addition to Virology.
His biological study spans a wide range of topics, including Interleukin 12, Toll-like receptor, TNF Receptor-Associated Factor 3 and Degranulation.
Pierre Lebon has included themes like Biomarker, Autoantibody and Encephalopathy in his Aicardi–Goutières syndrome study.
His Immune system course of study focuses on Downregulation and upregulation and Molecular biology, Cancer research, Lymph and In vitro.
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