World's Best Scientists 2026 revealed!

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Medicine

D-Index
80
Citations
24220
World Ranking
17084
National Ranking
542

Overview

Takeshi Azuma is affiliated with the Chiba Institute of Science in Japan and has contributed extensively to the field of medicine, with a particular focus on oncology and related biomedical sciences. Azuma's research spans multiple subfields including oncology, pulmonary and respiratory medicine, surgery, molecular biology, and ophthalmology.

The scientist's work addresses several main topics, primarily:

  • Cancer Immunotherapy and Biomarkers
  • Bladder and Urothelial Cancer Treatments
  • Retinal Diseases and Treatments
  • Immune Cell Function and Interaction
  • Renal Cell Carcinoma Treatment
  • Glaucoma and Retinal Disorders
  • Epigenetics and DNA Methylation

Selected recent papers authored or coauthored by Takeshi Azuma illustrate the range of their research interests. These include:

  • Serum soluble B7-H3 is a prognostic marker for patients with non-muscle-invasive bladder cancer, 2020, PLoS ONE
  • Polarization-Sensitive OCT Imaging of Scleral Abnormalities in Eyes With High Myopia and Dome-Shaped Macula, 2024, JAMA Ophthalmology
  • Nivolumab and Ipilimumab Combination Immunotherapy for Patients with Metastatic Collecting Duct Carcinoma, 2021, Case Reports in Urology
  • EXTREME MACULAR SCHISIS-SIMULATING RETINAL DETACHMENT IN EYES WITH PATHOLOGIC MYOPIA, 2022, Retina
  • Genome-Wide Association Study Adjusted for Occupational and Environmental Factors for Bladder Cancer Susceptibility, 2022, Genes

Azuma frequently collaborates with a group of coauthors, including:

  • Sachi Honda
  • Shohei Iwata
  • Fusako Niimi
  • Takumi Takeuchi
  • Tetsuya Danno

Publishing their work in several peer-reviewed venues, Takeshi Azuma has contributed multiple papers in outlets such as:

  • Molecular and Clinical Oncology
  • PLoS ONE
  • Retina
  • Cureus
  • Annals of the Rheumatic Diseases

This profile reflects a research career focused predominantly on medical applications related to cancer treatment and biomarkers, as well as ocular diseases. Azuma's interdisciplinary approach integrates aspects of molecular biology and clinical medicine to address complex medical challenges.

Best Publications

  • Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study

    H. J. N. Andreyev;A. R. Norman;D. Cunningham;J. Oates

  • Helicobacter pylori Caga Protein Can Be Tyrosine Phosphorylated in Gastric Epithelial Cells

    Momoyo Asahi;Takeshi Azuma;Shigeji Ito;Yoshiyuki Ito

  • Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

    Yuko Matsumoto;Hiroyuki Marusawa;Kazuo Kinoshita;Yoko Endo

  • Helicobacter pylori CagA interacts with E-cadherin and deregulates the β-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells

    N Murata-Kamiya;Y Kurashima;Y Teishikata;Y Yamahashi

  • B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells

    Takeshi Azuma;Sheng Yao;Gefeng Zhu;Andrew S. Flies

  • Recombination and clonal groupings within Helicobacter pylori from different geographical regions.

    M Achtman;T Azuma;D E Berg;Y Ito

  • Asia-Pacific consensus guidelines on gastric cancer prevention.

    Kwong Ming Fock;Nick Talley;Paul Moayyedi;Richard Hunt

  • Distinctiveness of Genotypes of Helicobacter pylori in Calcutta, India

    Asish K. Mukhopadhyay;Dangeruta Kersulyte;Jin-Yong Jeong;Simanti Datta

  • Analysis of human V alpha 24+ CD4+ NKT cells activated by alpha-glycosylceramide-pulsed monocyte-derived dendritic cells.

    Tsuyoshi Takahashi;Shigeru Chiba;Mie Nieda;Takeshi Azuma

  • Usefulness of selective arterial secretin injection test for localization of gastrinoma in the Zollinger-Ellison syndrome.

    Masayuki Imamura;Kiyoyuki Takahashi;Hideki Adachi;Souhei Minematsu

  • Evidence-based clinical practice guidelines for irritable bowel syndrome

    Shin Fukudo;Hiroshi Kaneko;Hirotada Akiho;Masahiko Inamori

  • Resolvin E1, an endogenous lipid mediator derived from eicosapentaenoic acid, prevents dextran sulfate sodium induced colitis

    Tsukasa Ishida;Masaru Yoshida;Makoto Arita;Yosuke Nishitani

  • Functional antagonism between Helicobacter pylori CagA and vacuolating toxin VacA in control of the NFAT signaling pathway in gastric epithelial cells

    Kazuyuki Yokoyama;Hideaki Higashi;Susumu Ishikawa;Yumiko Fujii

  • Recurrent Peptic Ulcers in Patients Following Successful Helicobacter pylori Eradication: A Multicenter Study of 4940 Patients

    Hiroto Miwa;Nobuhiro Sakaki;Kentaro Sugano;Hitoshi Sekine

  • B7-H4–deficient mice display augmented neutrophil-mediated innate immunity

    Gefeng Zhu;Mathew M. Augustine;Takeshi Azuma;Liqun Luo

  • Dichotomy in intrahepatic cholangiocarcinomas based on histologic similarities to hilar cholangiocarcinomas

    Masayuki Akita;Kohei Fujikura;Tetsuo Ajiki;Takumi Fukumoto

  • Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kappaB activation.

    Junzo Hisatsune;Masaaki Nakayama;Hajime Isomoto;Hisao Kurazono

  • Potential role of decoy B7-H4 in the pathogenesis of rheumatoid arthritis: a mouse model informed by clinical data.

    Takeshi Azuma;Gefeng Zhu;Haiying Xu;A. Cecilia Rietz

  • Helicobacter pylori infection occurs via close contact with infected individuals in early childhood.

    Hideki Miyaji;Takeshi Azuma;Shigeji Ito;Yoshimichi Abe

  • Gamma interferon produced by antigen-specific CD4+ T cells regulates the mucosal immune responses to Citrobacter rodentium infection.

    Hideyuki Shiomi;Atsuhiro Masuda;Shin Nishiumi;Masayuki Nishida

Frequent Co-Authors

Douglas E. Berg
Douglas E. Berg Washington University in St. Louis
Yutaka Shimada
Yutaka Shimada Kyoto University
Asish Mukhopadhyay
Asish Mukhopadhyay Indian Council of Medical Research
Sujit K. Bhattacharya
Sujit K. Bhattacharya Indian Council of Medical Research
G. Balakrish Nair
G. Balakrish Nair National Institute of Cholera and Enteric Diseases
Masayuki Imamura
Masayuki Imamura Kyoto University
Masashi Mizokami
Masashi Mizokami National Center For Global Health and Medicine
Chihiro Sasakawa
Chihiro Sasakawa Chiba University
Toshiyuki Sakai
Toshiyuki Sakai Kyoto Prefectural University of Medicine
Etsuro Orito
Etsuro Orito Japanese Red Cross Nagoya Daini Hospital

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