D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 70 Citations 17,654 263 World Ranking 4422 National Ranking 112

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Internal medicine

Philip Newsholme focuses on Biochemistry, Glutamine, Metabolism, Internal medicine and Endocrinology. His biological study deals with issues like Beta cell, which deal with fields such as NADPH oxidase and Oligomycin. His Glutamine research is multidisciplinary, relying on both Cytokine, Cell growth, Ketone bodies, Immune system and Cell biology.

His studies deal with areas such as Homeostasis and Function as well as Metabolism. Internal medicine is closely attributed to Type 2 diabetes in his study. His study deals with a combination of Endocrinology and Context.

His most cited work include:

  • Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes (896 citations)
  • Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity. (486 citations)
  • Glutamine and glutamate—their central role in cell metabolism and function (426 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Internal medicine, Endocrinology, Biochemistry, Insulin and Metabolism. As part of his studies on Internal medicine, Philip Newsholme often connects relevant areas like Type 2 diabetes. As a part of the same scientific study, he usually deals with the Endocrinology, concentrating on Inflammation and frequently concerns with Immune system.

His study explores the link between Biochemistry and topics such as Molecular biology that cross with problems in DNA fragmentation and Oleic acid. His Insulin study combines topics in areas such as Secretion and Intracellular. The various areas that Philip Newsholme examines in his Metabolism study include Macrophage and Alanine.

He most often published in these fields:

  • Internal medicine (44.03%)
  • Endocrinology (42.91%)
  • Biochemistry (33.21%)

What were the highlights of his more recent work (between 2014-2021)?

  • Internal medicine (44.03%)
  • Endocrinology (42.91%)
  • Cell biology (17.16%)

In recent papers he was focusing on the following fields of study:

Philip Newsholme mainly investigates Internal medicine, Endocrinology, Cell biology, Insulin and Insulin resistance. His studies in Internal medicine integrate themes in fields like Glutamine and Intracellular. In his research, Immune system is intimately related to Inflammation, which falls under the overarching field of Endocrinology.

Many of his research projects under Cell biology are closely connected to Population with Population, tying the diverse disciplines of science together. His Insulin research is multidisciplinary, incorporating elements of Diabetes mellitus and Secretion. His Metabolism research is under the purview of Biochemistry.

Between 2014 and 2021, his most popular works were:

  • Molecular mechanisms of ROS production and oxidative stress in diabetes. (269 citations)
  • Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer's Disease. (224 citations)
  • The Impact of Vitamin D Levels on Inflammatory Status: A Systematic Review of Immune Cell Studies (170 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Internal medicine

His primary areas of investigation include Internal medicine, Endocrinology, Insulin resistance, Inflammation and Biochemistry. Philip Newsholme works in the field of Internal medicine, focusing on NADPH oxidase in particular. His Endocrinology study combines topics from a wide range of disciplines, such as Cell biology, Sirtuin 1 and Mitochondrial biogenesis.

The various areas that he examines in his Insulin resistance study include Immunology, Metabolic syndrome, Type 2 diabetes and Intracellular. His Biochemistry study frequently links to adjacent areas such as Skeletal muscle. Philip Newsholme focuses mostly in the field of Insulin, narrowing it down to matters related to Oxidative stress and, in some cases, Reactive oxygen species.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Seth L Masters;Aisling Dunne;Shoba L Subramanian;Rebecca L Hull.
Nature Immunology (2010)

1256 Citations

Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity.

P. Newsholme;E. P. Haber;S. M. Hirabara;E. L. O. Rebelato.
The Journal of Physiology (2007)

736 Citations

Glutamine and glutamate—their central role in cell metabolism and function

Philip Newsholme;Joaquim Procopio;Manuela Maria Ramos Lima;Tania Cristina Pithon-Curi.
Cell Biochemistry and Function (2003)

690 Citations

Why Is l-Glutamine Metabolism Important to Cells of the Immune System in Health, Postinjury, Surgery or Infection?

Philip Newsholme.
Journal of Nutrition (2001)

633 Citations

Molecular mechanisms of glutamine action.

R. Curi;C.J. Lagranha;S.Q. Doi;D.F. Sellitti.
Journal of Cellular Physiology (2005)

493 Citations

Glutamine and glutamate as vital metabolites

P. Newsholme;M.M.R. Lima;J. Procopio;T.C. Pithon-Curi.
Brazilian Journal of Medical and Biological Research (2003)

447 Citations

Glutamine: Metabolism and immune function, supplementation and clinical translation

Vinicius Cruzat;Marcelo Macedo Rogero;Kevin Noel Keane;Rui Curi.
Nutrients (2018)

432 Citations

Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages.

P Newsholme;Rui Curi;S Gordon;E A Newsholme.
Biochemical Journal (1986)

432 Citations

Molecular mechanisms of ROS production and oxidative stress in diabetes.

Philip Newsholme;Vinicius Fernandes Cruzat;Vinicius Fernandes Cruzat;Kevin Noel Keane;Rodrigo Carlessi.
Biochemical Journal (2016)

360 Citations

Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages

P Newsholme;S Gordon;E A Newsholme.
Biochemical Journal (1987)

323 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Philip Newsholme

Rui Curi

Rui Curi

Universidade Cruzeiro do Sul

Publications: 168

Philip C. Calder

Philip C. Calder

University of Southampton

Publications: 93

Guoyao Wu

Guoyao Wu

Texas A&M University

Publications: 44

Yulong Yin

Yulong Yin

Chinese Academy of Sciences

Publications: 35

Luke A. J. O'Neill

Luke A. J. O'Neill

Trinity College Dublin

Publications: 31

Eicke Latz

Eicke Latz

University of Bonn

Publications: 30

Pierre Maechler

Pierre Maechler

University of Geneva

Publications: 23

Richard J. FitzGerald

Richard J. FitzGerald

University of Limerick

Publications: 21

Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

University of Copenhagen

Publications: 19

Marc Y. Donath

Marc Y. Donath

University of Basel

Publications: 19

Eric A. Newsholme

Eric A. Newsholme

University of Oxford

Publications: 19

Nicolaas E. P. Deutz

Nicolaas E. P. Deutz

Texas A&M University

Publications: 18

Seth L. Masters

Seth L. Masters

Walter and Eliza Hall Institute of Medical Research

Publications: 16

James E. Vince

James E. Vince

Walter and Eliza Hall Institute of Medical Research

Publications: 15

Richard A. Flavell

Richard A. Flavell

Yale University

Publications: 15

Amirhossein Sahebkar

Amirhossein Sahebkar

Mashhad University of Medical Sciences

Publications: 14

Trending Scientists

Remzi H. Arpaci-Dusseau

Remzi H. Arpaci-Dusseau

University of Wisconsin–Madison

Sanford Weisberg

Sanford Weisberg

University of Minnesota

Mahdi Jalili

Mahdi Jalili

RMIT University

Zhi-Hui Zhan

Zhi-Hui Zhan

South China University of Technology

Perumal Nithiarasu

Perumal Nithiarasu

Swansea University

Hartmut Michel

Hartmut Michel

Max Planck Society

Angel R. de Lera

Angel R. de Lera

Universidade de Vigo

Ulrike Kutay

Ulrike Kutay

ETH Zurich

Fatima Al-Shahrour

Fatima Al-Shahrour

Spanish National Cancer Research Centre

Denis Wirtz

Denis Wirtz

Johns Hopkins University

Marc R. Block

Marc R. Block

Grenoble Alpes University

Vincent Chevrier

Vincent Chevrier

University of Arkansas at Fayetteville

Catherine Liousse

Catherine Liousse

Paul Sabatier University

Marius Usher

Marius Usher

Tel Aviv University

Christine N. Metz

Christine N. Metz

Feinstein Institute for Medical Research

Inseok Song

Inseok Song

University of Georgia

Something went wrong. Please try again later.