His primary scientific interests are in Internal medicine, Dengue fever, Immunology, Virology and Retrospective cohort study. His Internal medicine research incorporates themes from Piperacillin/tazobactam, Piperacillin, Surgery and Carbapenem. His Piperacillin research is multidisciplinary, incorporating perspectives in Randomized controlled trial, Meropenem, Beta-lactamase, Drug resistance and Ceftriaxone.
His Dengue fever study integrates concerns from other disciplines, such as Viral disease, Confidence interval, Serology, Severity of illness and Pediatrics. His studies in Virology integrate themes in fields like Antibody, CD8, Communicable disease and Coronavirus. His biological study spans a wide range of topics, including Case-control study and Dengue hemorrhagic fever.
His scientific interests lie mostly in Internal medicine, Dengue fever, Retrospective cohort study, Immunology and Intensive care medicine. His Internal medicine research focuses on Surgery and how it relates to Platelet transfusion. His studies examine the connections between Dengue fever and genetics, as well as such issues in Hematocrit, with regards to Abdominal pain.
His Retrospective cohort study research includes themes of Cohort study, Relative risk, Severity of illness, Intensive care unit and Cohort. His work investigates the relationship between Cohort study and topics such as Prospective cohort study that intersect with problems in Emergency medicine. His study in Ceftriaxone and Carbapenem are all subfields of Antibiotics.
Internal medicine, Coronavirus disease 2019, Immunology, Severe acute respiratory syndrome coronavirus 2 and Antibody are his primary areas of study. Internal medicine is closely attributed to Dengue fever in his research. David C. Lye interconnects Disease severity, Radiography, Virology, Pneumonia and 2019-20 coronavirus outbreak in the investigation of issues within Coronavirus disease 2019.
His Virology study combines topics in areas such as Epitope and Coronavirus. His research in Severe acute respiratory syndrome coronavirus 2 intersects with topics in Gastroenterology and Pandemic. His Antibody research is multidisciplinary, relying on both Virus, Asymptomatic and Convalescence.
David C. Lye spends much of his time researching Coronavirus disease 2019, Virology, Antibody, Severe acute respiratory syndrome coronavirus 2 and 2019-20 coronavirus outbreak. His Coronavirus disease 2019 research integrates issues from Venous thrombosis, Pediatrics, Disease severity and Acute disseminated encephalomyelitis. His work deals with themes such as Serology, Respiratory tract infections and Coronavirus, which intersect with Virology.
As part of one scientific family, he deals mainly with the area of Antibody, narrowing it down to issues related to the Virus, and often Open reading frame, Genome and Outbreak. His research integrates issues of Observational study, Repeat testing, Pandemic, Betacoronavirus and Cohort in his study of 2019-20 coronavirus outbreak. His research on Pneumonia concerns the broader Internal medicine.
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Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore.
Barnaby Edward Young;Sean Wei Xiang Ong;Shirin Kalimuddin;Shirin Kalimuddin;Jenny G. Low;Jenny G. Low.
JAMA (2020)
Remdesivir for 5 or 10 Days in Patients with Severe Covid-19.
Jason D. Goldman;David C.B. Lye;David S. Hui;Kristen M. Marks.
The New England Journal of Medicine (2020)
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19.
Andre C Kalil;Thomas F Patterson;Aneesh K Mehta;Kay M Tomashek.
The New England Journal of Medicine (2021)
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail.
Johanna Hansen;Alina Baum;Kristen E. Pascal;Vincenzo Russo.
Science (2020)
A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction.
Chee Wah Tan;Wan Ni Chia;Xijian Qin;Pei Liu.
Nature Biotechnology (2020)
Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures.
Rachael Pung;Calvin J. Chiew;Barnaby E. Young;Sarah Chin.
The Lancet (2020)
Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance A Randomized Clinical Trial
Patrick N. A. Harris;Patrick N. A. Harris;Patrick N. A. Harris;Paul A. Tambyah;David C. Lye;David C. Lye;David C. Lye;Yin Mo.
JAMA (2018)
Assessing Viral Shedding and Infectivity of Tears in Coronavirus Disease 2019 (COVID-19) Patients.
Ivan Yu Jun Seah;Danielle E. Anderson;Adrian Eng Zheng Kang;Linfa Wang.
Ophthalmology (2020)
Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients.
Chek Meng Poh;Guillaume Carissimo;Bei Wang;Siti Naqiah Amrun.
Nature Communications (2020)
Antimicrobial consumption and resistance in adult hospital inpatients in 53 countries: results of an internet-based global point prevalence survey.
Ann Versporten;Peter Zarb;Isabelle Caniaux;Marie Françoise Gros.
The Lancet Global Health (2018)
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