Irving Boime

Overview

Best Publications

• Design of a long-acting follitropin agonist by fusing the C-terminal sequence of the chorionic gonadotropin beta subunit to the follitropin beta subunit

  F. A. Fares;N. Suganuma;K. Nishimori;P. S. Lapolt

  337
  Citations

• Expression of biologically active human follitropin in Chinese hamster ovary cells.

  J. L. Keene;M. M. Matzuk;T. Otani;B. C. J. M. Fauser

  289
  Citations

• Site specificity of the chorionic gonadotropin N-linked oligosaccharides in signal transduction.

  M M Matzuk;J L Keene;I Boime

  276
  Citations

• The biological role of the carboxyl-terminal extension of human chorionic gonadotropin [corrected] beta-subunit.

  M.M. Matzuk;A.J.W. Hsueh;A.J.W. Hsueh;P. Lapolt;P. Lapolt;A. Tsafriri;A. Tsafriri

  273
  Citations

• A single gonadotropin alpha-subunit gene in normal tissue and tumor-derived cell lines.

  M Boothby;R W Ruddon;C Anderson;D McWilliams

  263
  Citations

• The role of the asparagine-linked oligosaccharides of the alpha subunit in the secretion and assembly of human chorionic gonadotrophin.

  Martin M. Matzuk;Irving Boime

  256
  Citations

• Transgenic models to study gonadotropin function: the role of follicle-stimulating hormone in gonadal growth and tumorigenesis.

  T. Rajendra Kumar;Ganesh Palapattu;Pei Wang;Teresa K. Woodruff

  205
  Citations

• Cytological localization of chorionic gonadotropin alpha and placental lactogen mRNAs during development of the human placenta.

  M Hoshina;M Boothby;I Boime

  202
  Citations

• Advances in recombinant DNA technology: corifollitropin alfa, a hybrid molecule with sustained follicle-stimulating activity and reduced injection frequency

  Bart Fauser;Bernadette Mannaerts;Paul Devroey;Leader A

  193
  Citations

• Identification of the transcriptionally active genes of the chorionic gonadotropin beta gene cluster in vivo.

  M Bo;I Boime

  191
  Citations

• The beta subunit of human chorionic gonadotropin is encoded by multiple genes.

  P Policastro;C E Ovitt;M Hoshina;H Fukuoka

  191
  Citations

• Structural elucidation of the disulfated oligosaccharide from bovine lutropin.

  E D Green;H van Halbeek;I Boime;J U Baenziger

  174
  Citations

• Expression of human luteinizing hormone (LH) receptor: interaction with LH and chorionic gonadotropin from human but not equine, rat, and ovine species.

  Xiao-Chi Jia;M. Oikawa;M. Bo;T. Tanaka

  169
  Citations

• Protein Synthesis Directed by Encephalomyocarditis Virus RNA: Properties of a Transfer RNA-Dependent System

  H. Aviv;I. Boime;P. Leder

  164
  Citations

• In Vitro and in Vivo Bioactivity of Recombinant Human Follicle-Stimulating Hormone and Partially Deglycosylated Variants Secreted by Transfected Eukaryotic Cell Lines*

  A. Brenda Galway;Aaron J. W. Hsueh;J. L. Keene;J. L. Keene;M. Yamoto;M. Yamoto

  159
  Citations

• Gonadotropin Beta Subunits Determine the Rate of Assembly and the Oligosaccharide Processing of Hormone Dimer in Transfected Cells

  Christopher L. Corless;Martin M. Matzuk;Triprayar V. Ramabhadran;Alexander Krichevsky

  158
  Citations

• Effects of preventing O-glycosylation on the secretion of human chorionic gonadotropin in Chinese hamster ovary cells

  Martin M. Matzuk;Monty Krieger;Christopher L. Corless;Irving Boime

  155
  Citations

• mRNA-dependent synthesis of authentic precursor to human placental lactogen: conversion to its mature hormone form in ascites cell-free extracts

  Elzbieta Szczesna;Irving Boime

  152
  Citations

• A map of the hCG beta-LH beta gene cluster.

  P. F. Policastro;S. Daniels-McQueen;G. Carle;Irving Boime

  151
  Citations

• Elimination of disulfide bonds affects assembly and secretion of the human chorionic gonadotropin β subunit

  N Suganuma;N Suganuma;M M Matzuk;I Boime

  148
  Citations