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Microbiology

D-Index
73
Citations
20556
World Ranking
1646
National Ranking
706

Overview

George Sakoulas is affiliated with the University of California, San Diego in the United States. Their primary area of research is within the field of Medicine, with a focus on Infectious Diseases, Epidemiology, Pharmacology, Molecular Biology, and Clinical Biochemistry. Over the course of their career, they have contributed to 193 publications in these areas.

The scientist's work centers on topics related to antimicrobial resistance and antibiotic efficacy. Major themes include:

  • Antimicrobial Resistance in Staphylococcus
  • Antibiotics Pharmacokinetics and Efficacy
  • Bacterial Identification and Susceptibility Testing
  • COVID-19 Clinical Research Studies
  • Antibiotic Use and Resistance
  • Antibiotic Resistance in Bacteria
  • Bacterial biofilms and quorum sensing

Some of their recent papers include:

  • Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures (2020, Cell)
  • Current Paradigms of Combination Therapy in Methicillin-Resistant Staphylococcus aureus (MRSA) Bacteremia: Does it Work, Which Combination, and For Which Patients? (2021, Clinical Infectious Diseases)
  • Acute Psychosis Due to Anti-N-Methyl D-Aspartate Receptor Encephalitis Following COVID-19 Vaccination: A Case Report (2021, Frontiers in Neurology)
  • Intravenous Immunoglobulin Plus Methylprednisolone Mitigate Respiratory Morbidity in Coronavirus Disease 2019 (2020, Critical Care Explorations)
  • Repurposed drugs block toxin-driven platelet clearance by the hepatic Ashwell-Morell receptor to clear Staphylococcus aureus bacteremia (2021, Science Translational Medicine)

Frequent publication venues for their work include:

  • Journal watch
  • Open Forum Infectious Diseases
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Infectious Diseases
  • Antimicrobial Agents and Chemotherapy

George Sakoulas collaborates regularly with several researchers, including:

  • Victor Nizet
  • Matthew Geriak
  • Warren E. Rose
  • Erlinda R. Ulloa
  • Satoshi Uchiyama

Best Publications

  • Comparison of mortality associated with methicillin-resistant and methicillin-susceptible staphylococcus aureus bacteremia: A meta-analysis

    Sara E. Cosgrove;George Sakoulas;Eli N. Perencevich;Mitchell J. Schwaber

  • Linezolid resistance in a clinical isolate of Staphylococcus aureus

    Sotirios Tsiodras;Sotirios Tsiodras;Howard S Gold;Howard S Gold;George Sakoulas;George Sakoulas;George M Eliopoulos;George M Eliopoulos

  • Relationship of MIC and Bactericidal Activity to Efficacy of Vancomycin for Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia

    George Sakoulas;Pamela A. Moise-Broder;Jerome Schentag;Alan Forrest

  • Accessory Gene Regulator (agr) Locus in Geographically Diverse Staphylococcus aureus Isolates with Reduced Susceptibility to Vancomycin

    George Sakoulas;George M. Eliopoulos;Robert C. Moellering;Christine Wennersten

  • Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein.

    Vance G. Fowler;George Sakoulas;Lauren M. McIntyre;Lauren M. McIntyre;Venkata G. Meka

  • Failures in Clinical Treatment of Staphylococcus aureus Infection with Daptomycin Are Associated with Alterations in Surface Charge, Membrane Phospholipid Asymmetry, and Drug Binding

    Tiffanny Jones;Michael R. Yeaman;Michael R. Yeaman;Michael R. Yeaman;George Sakoulas;Soo-Jin Yang

  • Accessory Gene Regulator Group II Polymorphism in Methicillin-Resistant Staphylococcus aureus Is Predictive of Failure of Vancomycin Therapy

    Pamela A. Moise-Broder;George Sakoulas;George M. Eliopoulos;Jerome J. Schentag

  • Increasing Antibiotic Resistance among Methicillin-Resistant Staphylococcus aureus Strains

    George Sakoulas;Robert C. Moellering

  • Induction of Daptomycin Heterogeneous Susceptibility in Staphylococcus aureus by Exposure to Vancomycin

    George Sakoulas;Jeff Alder;Claudie Thauvin-Eliopoulos;Robert C. Moellering

  • Use of Antistaphylococcal β-Lactams to Increase Daptomycin Activity in Eradicating Persistent Bacteremia Due to Methicillin-Resistant Staphylococcus aureus: Role of Enhanced Daptomycin Binding

    Abhay Dhand;Arnold S. Bayer;Arnold S. Bayer;Joseph Pogliano;Soo-Jin Yang;Soo-Jin Yang

  • Linezolid Resistance in Sequential Staphylococcus aureus Isolates Associated with a T2500A Mutation in the 23S rRNA Gene and Loss of a Single Copy of rRNA

    Venkata G. Meka;Satish K. Pillai;George Sakoulas;Christine Wennersten

  • Vancomycin in vitro bactericidal activity and its relationship to efficacy in clearance of methicillin-resistant Staphylococcus aureus Bacteremia

    Pamela A. Moise;George Sakoulas;Alan Forrest;Jerome J. Schentag

  • Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens

    Leo Lin;Poochit Nonejuie;Jason Munguia;Andrew Hollands

  • Methicillin-Resistant Staphylococcus aureus: Comparison of Susceptibility Testing Methods and Analysis of mecA-Positive Susceptible Strains

    George Sakoulas;Howard S. Gold;Lata Venkataraman;Paola C. DeGirolami

  • Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia

    Marin L Schweizer;Marin L Schweizer;Jon P Furuno;Anthony D Harris;J Kristie Johnson

  • Staphylococcus aureus Accessory Gene Regulator (agr) Group II: Is There a Relationship to the Development of Intermediate-Level Glycopeptide Resistance?

    George Sakoulas;George M. Eliopoulos;Robert C. Moellering;Richard P. Novick

  • A Current Perspective on Daptomycin for the Clinical Microbiologist

    Romney M. Humphries;Simon Pollett;George Sakoulas

  • Linezolid Resistance in Staphylococcus aureus: Characterization and Stability of Resistant Phenotype

    Satish K. Pillai;George Sakoulas;George Sakoulas;Christine Wennersten;George M. Eliopoulos;George M. Eliopoulos

  • Adaptation of Methicillin-Resistant Staphylococcus aureus in the Face of Vancomycin Therapy

    George Sakoulas;Robert C. Moellering;George M. Eliopoulos

  • Perspectives on Daptomycin Resistance, with Emphasis on Resistance in Staphylococcus aureus

    Helen W. Boucher;George Sakoulas;George Sakoulas

Frequent Co-Authors

Victor Nizet
Victor Nizet University of California, San Diego
Michael J. Rybak
Michael J. Rybak Wayne State University
Joe Pogliano
Joe Pogliano University of California, San Diego
Arnold S. Bayer
Arnold S. Bayer University of California, Los Angeles
George M. Eliopoulos
George M. Eliopoulos Beth Israel Deaconess Medical Center
Michael R. Yeaman
Michael R. Yeaman University of California, Los Angeles
Robert C. Moellering
Robert C. Moellering Beth Israel Deaconess Medical Center
Marcus J. Zervos
Marcus J. Zervos Wayne State University
Brian T. Tsuji
Brian T. Tsuji University at Buffalo, State University of New York
Yan Q. Xiong
Yan Q. Xiong University of California, Los Angeles

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