Rakesh K. Srivastava

Best Publications

• Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways.

  Unknown

  554
  Citations

• Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase.

  Rakesh K. Srivastava;Aparna R. Srivastava;Stanley J. Korsmeyer;Maria Nesterova

  477
  Citations

• Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

  R K Srivastava;Q S Mi;J M Hardwick;D L Longo

  437
  Citations

• Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential

  Unknown

  434
  Citations

• Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer

  Unknown

  395
  Citations

• Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition.

  Unknown

  380
  Citations

• TRAIL/Apo-2L : mechanisms and clinical applications in cancer

  Unknown

  353
  Citations

• Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells.

  Unknown

  311
  Citations

• Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications

  Unknown

  298
  Citations

• Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer

  Unknown

  288
  Citations

• Involvement of Proapoptotic Molecules Bax and Bak in Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Mitochondrial Disruption and Apoptosis: Differential Regulation of Cytochrome c and Smac/DIABLO Release

  Karthikeyan Kandasamy;Srinivasa M Srinivasula;Emad S Alnemri;Craig B Thompson

  283
  Citations

• Differential Roles of RelA (p65) and c-Rel Subunits of Nuclear Factor κB in Tumor Necrosis Factor-related Apoptosis-inducing Ligand Signaling

  Unknown

  280
  Citations

• The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition

  Unknown

  268
  Citations

• Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway.

  Unknown

  233
  Citations

• Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells

  Unknown

  229
  Citations

• Green tea polyphenols: biology and therapeutic implications in cancer.

  Unknown

  226
  Citations

• Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosis.

  Rakesh K. Srivastava;Steven J. Sollott;Leila Khan;Richard Hansford

  215
  Citations

• Resveratrol Induces Growth Arrest and Apoptosis through Activation of FOXO Transcription Factors in Prostate Cancer Cells

  Unknown

  214
  Citations

• Histone deacetylase inhibitors: mechanisms and clinical significance in cancer: HDAC inhibitor-induced apoptosis.

  Unknown

  209
  Citations

• Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma.

  Tamer E. Fandy;Sharmila Shankar;Douglas D. Ross;Edward Sausville

  207
  Citations