World's Best Scientists 2026 revealed!
Takahisa Kanekiyo

Takahisa Kanekiyo

D-Index & Metrics

Neuroscience

D-Index
60
Citations
15863
World Ranking
3792
National Ranking
1734

Takahisa Kanekiyo publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Takahisa Kanekiyo sits on this spectrum.

38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientists 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38 publications 887+

This scientist: 130 publications — 33rd percentile

33% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

Takahisa Kanekiyo D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Takahisa Kanekiyo sits on this spectrum.

30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30 D-Index 163+

This scientist: 60 D-Index — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

Overview

Takahisa Kanekiyo is affiliated with the Mayo Clinic in the United States. Their research primarily focuses on Alzheimer's disease and related neurological conditions, examining molecular mechanisms and pathological processes underlying these disorders.

Their recent scholarly contributions include:

  • APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids, 2020, Nature Communications
  • ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias, 2022, Neuron
  • Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways, 2020, Neuron
  • Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease, 2023, Molecular Neurodegeneration
  • Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function, 2022, Nature Neuroscience

Frequent collaborators in their research include:

  • Guojun Bu
  • Yuka A. Martens
  • Yingxue Ren
  • Chia-Chen Liu
  • Dennis W. Dickson

The venues where Takahisa Kanekiyo has consistently published reflect a focus on neuroscientific and neurodegenerative disease research:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuron
  • Molecular Neurodegeneration
  • Science Advances

Their work spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in subfields such as Molecular Biology, Physiology, Neurology, Surgery, and Cellular and Molecular Neuroscience.

Main research topics addressed in their publications consist of:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • RNA Interference and Gene Delivery
  • Cholesterol and Lipid Metabolism
  • Mitochondrial Function and Pathology
  • Dementia and Cognitive Impairment Research
  • Epigenetics and DNA Methylation

This broad spectrum of topics encompasses molecular insights into neurodegenerative diseases, exploring genetic risk factors and cellular mechanisms that influence disease progression and cognition. The research integrates molecular biology with clinical neuroscience to elucidate pathways involved in Alzheimer's disease and vascular contributions to cognitive impairment.

Best Publications

  • Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

    Chia Chan Liu;Takahisa Kanekiyo;Huaxi Xu;Guojun Bu

  • ApoE and Aβ in Alzheimer's disease: accidental encounters or partners?

    Takahisa Kanekiyo;Huaxi Xu;Guojun Bu;Guojun Bu

  • Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

    Zhen Zhao;Abhay P Sagare;Qingyi Ma;Matthew R Halliday

  • Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer's Disease.

    Yu Yamazaki;Takahisa Kanekiyo

  • APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids

    Jing Zhao;Yuan Fu;Yu Yamazaki;Yingxue Ren

  • APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease

    Katherine L. Youmans;Leon M. Tai;Evelyn Nwabuisi-Heath;Lisa Jungbauer

  • Neuronal Clearance of Amyloid-β by Endocytic Receptor LRP1

    Takahisa Kanekiyo;John R. Cirrito;Chia Chen Liu;Chia Chen Liu;Mitsuru Shinohara

  • The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's disease.

    Takahisa Kanekiyo;Guojun Bu

  • Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies.

    Mitsuru Shinohara;Masaya Tachibana;Takahisa Kanekiyo;Guojun Bu

  • Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease

    Unknown

  • LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.

    Takahisa Kanekiyo;Chia Chen Liu;Chia Chen Liu;Mitsuru Shinohara;Jie Li;Jie Li

  • Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition.

    Chia Chen Liu;Jin Hu;Jin Hu;Na Zhao;Jian Wang

  • The role of APOE in cerebrovascular dysfunction

    Leon M. Tai;Riya Thomas;Felecia M. Marottoli;Kevin P. Koster

  • Vascular Cell Senescence Contributes to Blood–Brain Barrier Breakdown

    Yu Yamazaki;Darren J. Baker;Masaya Tachibana;Chia Chen Liu

  • Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.

    Takahisa Kanekiyo;Juan Zhang;Qiang Liu;Chia Chen Liu

  • Deficiency in LRP6-Mediated Wnt Signaling Contributes to Synaptic Abnormalities and Amyloid Pathology in Alzheimer’s Disease

    Chia-Chen Liu;Chia-Chen Liu;Chih-Wei Tsai;Ferenc Deak;Ferenc Deak;Justin Rogers

  • Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways.

    Na Zhao;Yingxue Ren;Yu Yamazaki;Wenhui Qiao

  • APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes.

    Jing Zhao;Mary D. Davis;Yuka A. Martens;Mitsuru Shinohara

  • Prostaglandin D2-Mediated Microglia/Astrocyte Interaction Enhances Astrogliosis and Demyelination in twitcher

    Ikuko Mohri;Masako Taniike;Hidetoshi Taniguchi;Takahisa Kanekiyo

  • Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease.

    Chia Chen Liu;Na Zhao;Yu Yamaguchi;John R. Cirrito

  • Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

    Katherine L. Youmans;Leon M. Tai;Takahisa Kanekiyo;W. Blaine Stine

  • Lipocalin-type prostaglandin D synthase/β-trace is a major amyloid β-chaperone in human cerebrospinal fluid

    Takahisa Kanekiyo;Tadato Ban;Kosuke Aritake;Zhi Li Huang;Zhi Li Huang

Frequent Co-Authors

Guojun Bu
Guojun Bu Hong Kong University of Science and Technology
Yan W. Asmann
Yan W. Asmann Mayo Clinic
Huaxi Xu
Huaxi Xu Xiamen University
Xianlin Han
Xianlin Han The University of Texas Health Science Center at San Antonio
Yoshihiro Urade
Yoshihiro Urade University of Tsukuba

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Related Online Degrees & Career Pathways

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Each of these online degrees complements a neuroscience background, equipping students for diverse careers in healthcare, education, and mental health support.

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