World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
55
Citations
14362
World Ranking
3561
National Ranking
423

Overview

Lorraine Southam is affiliated with the Wellcome Sanger Institute in the United Kingdom. Their research primarily focuses on genetics and related medical fields, with a notable emphasis on osteoarthritis and genetic epidemiology.

The scientific inquiry carried out by Lorraine Southam spans several main fields of study:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these areas, the scientist has contributed extensively to various subfields, including:

  • Genetics
  • Rheumatology
  • Cancer Research
  • Surgery
  • Molecular Biology

Key topics addressed in their work encompass:

  • Osteoarthritis Treatment and Mechanisms
  • Genetic Associations and Epidemiology
  • Cancer-related molecular mechanisms research
  • Inflammatory mediators and NSAID effects
  • Cytokine Signaling Pathways and Interactions
  • Genetic and phenotypic traits in livestock
  • Hip disorders and treatments

Among frequent co-authors collaborating with Lorraine Southam are:

  • Eleftheria Zeggini (44 collaborations)
  • Konstantinos Hatzikotoulas (28 collaborations)
  • J. Mark Wilkinson (22 collaborations)
  • Julia Steinberg (18 collaborations)
  • Cindy G. Boer (17 collaborations)

Key publication venues reflect the areas of expertise and research impact:

  • Osteoarthritis and Cartilage (17 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (10 publications)
  • Nature Communications (6 publications)
  • Annals of the Rheumatic Diseases (3 publications)
  • UNC Libraries (3 publications)

Recent notable papers authored or co-authored by Lorraine Southam include:

  • The trans-ancestral genomic architecture of glycemic traits, 2021, Nature Genetics
  • Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations, 2021, Cell
  • Genetic drivers of heterogeneity in type 2 diabetes pathophysiology, 2024, Nature
  • Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations, 2021, Cell
  • Whole-genome sequencing analysis of the cardiometabolic proteome, 2020, Nature Communications

Best Publications

  • The trans-ancestral genomic architecture of glycemic traits

    Ji Chen;Ji Chen;Cassandra N. Spracklen;Cassandra N. Spracklen;Gaëlle Marenne;Gaëlle Marenne;Arushi Varshney

  • The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    Thomas W. Winkler;Anne E. Justice;Mariaelisa Graff;Llilda Barata

  • Exome-wide association study of plasma lipids in > 300,000 individuals

    Dajiang J Liu;Gina M Peloso;Gina M Peloso;Haojie Yu;Adam S Butterworth;Adam S Butterworth

  • Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females

    John Loughlin;Barbara Dowling;Kay Chapman;Lucy Marcelline

  • Identification of new susceptibility loci for osteoarthritis (arcOGEN): A genome-wide association study

    E Zeggini;K Panoutsopoulou

  • Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.

    Ioanna Tachmazidou;Konstantinos Hatzikotoulas;Lorraine Southam;Lorraine Southam;Jorge Esparza-Gordillo

  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Valérie Turcot;Yingchang Lu;Yingchang Lu;Heather M Highland;Heather M Highland;Claudia Schurmann

  • Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

    Jie Huang;Bryan Howie;Shane McCarthy;Yasin Memari

  • Correction: Corrigendum: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

    Miriam Schmidts;Yuqing Hou;Claudio R. Cortes;Dorus A. Mans

  • Linkage and Association Analysis of Angiotensin I–Converting Enzyme (ACE)–Gene Polymorphisms with ACE Concentration and Blood Pressure

    Xiaofeng Zhu;Nourdine Bouzekri;Lorraine Southam;Richard S. Cooper

  • Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    Praveen Surendran;Fotios Drenos;Robin Young;Helen Warren

  • Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

    Cindy G Boer;Konstantinos Hatzikotoulas;Lorraine Southam;Lilja Stefánsdóttir

  • Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis

    Eleni Zengini;Konstantinos Hatzikotoulas;Ioanna Tachmazidou;Julia Steinberg;Julia Steinberg

  • An SNP in the 5′-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage

    Lorraine Southam;Julio Rodriguez-Lopez;James M. Wilkins;Manuel Pombo-Suarez

  • A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5′ UTR of GDF5 with osteoarthritis susceptibility

    Kay Chapman;Atsushi Takahashi;Ingrid Meulenbelt;Chris Watson

  • Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

    Jennifer Wessel;Audrey Y. Chu;Sara M. Willems;Shuai Wang

  • Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

    Ioanna Tachmazidou;Dániel Süveges;Josine L. Min;Graham R.S. Ritchie;Graham R.S. Ritchie

  • Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

    Jennifer Wessel;Audrey Y. Chu;Sara M. Willems;Shuai Wang

  • Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

    Lee Ph;Anttila;Won H

  • The Trans-Ancestral Genomic Architecture of Glycaemic Traits

    Ji Chen;Ji Chen;Cassandra N. Spracklen;Cassandra N. Spracklen;Gaëlle Marenne;Gaëlle Marenne;Arushi Varshney

Frequent Co-Authors

Eleftheria Zeggini
Eleftheria Zeggini Technical University of Munich
Nigel W. Rayner
Nigel W. Rayner University of Oxford
George Dedoussis
George Dedoussis Harokopio University
Jaspal S. Kooner
Jaspal S. Kooner Imperial College London
John C. Chambers
John C. Chambers Guy's and St Thomas' NHS Foundation Trust
Paul W. Franks
Paul W. Franks Lund University
Panos Deloukas
Panos Deloukas Queen Mary University of London
Weihua Zhang
Weihua Zhang Imperial College London
Cecilia M. Lindgren
Cecilia M. Lindgren University of Oxford

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a degree in Genetics opens up a range of dynamic career pathways and related online programs. Students often start by building foundational skills through specialized certificate programs like medical billing and coding programs—an option for those interested in healthcare administration and the medical field.

Many students look for flexibility and speed as they pursue their education. Consider fast track college programs if you want to accelerate your studies and graduate sooner. Some institutions also offer flexible learning through the best accredited self-paced online colleges, allowing you to balance your studies with work or personal commitments.

If application fees are a concern, explore your options with a free online college application. This can help reduce upfront costs and make your educational journey more affordable. By researching these pathways, you can find the right fit for your interests and career goals in genetics or related fields.

Best Scientists Citing Lorraine Southam

Trending Scientists

Recently Published Articles