John C. Hutton

Overview

Best Publications

• Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

  Robert S. Jackson;John W.M. Creemers;Shinya Ohagi;Marie-Laure Raffin-Sanson

  1326
  Citations

• The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

  Janet M. Wenzlau;Kirstine Juhl;Kirstine Juhl;Liping Yu;Ong Moua

  1290
  Citations

• Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice.

  Maki Nakayama;Norio Abiru;Hiroaki Moriyama;Naru Babaya

  1101
  Citations

• The stimulus-secretion coupling of glucose-induced insulin release. XXXV. The links between metabolic and cationic events.

  Willy Malaisse;Willy Malaisse;J C Hutton;Shoji Kawazu;André Herchuelz

  609
  Citations

• Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic β cell via two distinct site-specific endopeptidases

  Howard W. Davidson;Christopher J. Rhodes;John C. Hutton

  550
  Citations

• Insulin release: the fuel hypothesis.

  Willy Malaisse;Abdullah Sener;André Herchuelz;J C Hutton

  418
  Citations

• Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

  Robert S Jackson;John W M Creemers;I Sadaf Farooqi;Marie-Laure Raffin-Sanson

  385
  Citations

• Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes.

  Christina Wasmeier;John C. Hutton;John C. Hutton

  328
  Citations

• Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes.

  M. S. Hurlbert;Wenbo Zhou;C. Wasmeier;F. G. Kaddis

  272
  Citations

• Enterovirus Infection and Progression from Islet Autoimmunity to Type 1 Diabetes: The Diabetes and Autoimmunity Study in the Young (DAISY)

  Lars C. Stene;Sami Oikarinen;Heikki Hyöty;Katherine J. Barriga

  267
  Citations

• Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction.

  Sean W. Limesand;Paul J. Rozance;Gary O. Zerbe;John C. Hutton

  265
  Citations

• A Common Nonsynonymous Single Nucleotide Polymorphism in the SLC30A8 Gene Determines ZnT8 Autoantibody Specificity in Type 1 Diabetes

  Janet M. Wenzlau;Yu Liu;Liping Yu;Ong Moua

  256
  Citations

• T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins

  Bart O. Roep;Susan D. Arden;René R. P. de vries;John C. Hutton

  254
  Citations

• Age of Islet Autoantibody Appearance and Mean Levels of Insulin, but Not GAD or IA-2 Autoantibodies, Predict Age of Diagnosis of Type 1 Diabetes: Diabetes Autoimmunity Study in the Young

  Andrea K. Steck;Kelly Johnson;Katherine J. Barriga;Dongmei Miao

  231
  Citations

• Glucose-6-phosphatase Catalytic Subunit Gene Family

  John C. Hutton;Richard M. O'Brien

  225
  Citations

• The internal pH and membrane potential of the insulin-secretory granule

  John C. Hutton

  219
  Citations

• Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion

  Lynley D. Pound;Suparna A. Sarkar;Richard K. P. Benninger;Yingda Wang

  214
  Citations

• In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice.

  D Healey;P Ozegbe;S Arden;P Chandler

  203
  Citations

• Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction

  Sean W. Limesand;Jan Jensen;John C. Hutton;William W. Hay

  196
  Citations

• The Stimulus‐Secretion Coupling of Glucose‐Induced Insulin Release

  Willy J. Malaisse;John. Hutton;Shoji Kawazu;Abdullah Sener

  189
  Citations