What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Immunology, Biochemistry, Endocrinology, Internal medicine and Insulin.
His work on Type 1 diabetes expands to the thematically related Immunology.
His biological study spans a wide range of topics, including Autoantibody, Autoimmune disease, Autoimmunity and SLC30A8.
His Biochemistry research incorporates elements of Molecular biology and Proinsulin.
His research integrates issues of Phosphatase and Molecular cloning in his study of Molecular biology.
His Endocrinology research incorporates themes from Missense mutation and Compound heterozygosity.
His most cited work include:
- Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene (917 citations)
- The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes (762 citations)
- Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. (638 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Immunology, Biochemistry, Internal medicine, Endocrinology and Molecular biology.
His research on Immunology frequently connects to adjacent areas such as Type 1 diabetes.
Many of his studies involve connections with topics such as Proinsulin and Biochemistry.
His study in the fields of Insulitis under the domain of Internal medicine overlaps with other disciplines such as Enteroendocrine cell.
His research in the fields of Insulin, Islet and Pancreatic islets overlaps with other disciplines such as Pancreatic hormone.
His Molecular biology study also includes fields such as
- Gene, which have a strong connection to Glucose 6-phosphatase,
- Transmembrane protein that intertwine with fields like Phosphatase, Exocytosis and Protein tyrosine phosphatase.
He most often published in these fields:
- Immunology (29.03%)
- Biochemistry (27.96%)
- Internal medicine (26.34%)
What were the highlights of his more recent work (between 2010-2015)?
- Autoantibody (22.58%)
- Type 1 diabetes (22.58%)
- Immunology (29.03%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Autoantibody, Type 1 diabetes, Immunology, Diabetes mellitus and Human leukocyte antigen.
His Autoantibody research integrates issues from Internal medicine, Endocrinology and SLC30A8.
John C. Hutton has researched Endocrinology in several fields, including Interferon gamma and In vivo.
The Type 1 diabetes study combines topics in areas such as CD8 and Genotype.
His work on Autoimmunity and Antigen as part of general Immunology research is frequently linked to pernicious anemia, thereby connecting diverse disciplines of science.
The various areas that he examines in his Diabetes mellitus study include Insulin and Pediatrics.
Between 2010 and 2015, his most popular works were:
- Age of Islet Autoantibody Appearance and Mean Levels of Insulin, but Not GAD or IA-2 Autoantibodies, Predict Age of Diagnosis of Type 1 Diabetes: Diabetes Autoimmunity Study in the Young (118 citations)
- Diabetes Antibody Standardization Program: First Proficiency Evaluation of Assays for Autoantibodies to Zinc Transporter 8 (85 citations)
- Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies. (65 citations)
In his most recent research, the most cited papers focused on:
John C. Hutton mainly focuses on Autoantibody, Type 1 diabetes, Immunology, Diabetes mellitus and Autoimmunity.
The concepts of his Type 1 diabetes study are interwoven with issues in Human leukocyte antigen, Insulin, Disease and Diabetes risk.
John C. Hutton has included themes like Molecular biology, Stimulation and Islet in his Immunology study.
His study in Autoimmunity is interdisciplinary in nature, drawing from both Transporter, Beta cell, CD8, Epitope and Cytotoxic T cell.
His Zinc Transporter 8 research also covers Endocrinology and Internal medicine studies.
His Endocrinology research includes elements of G6PC2 and In vivo.
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