His primary areas of investigation include Immunology, Biochemistry, Endocrinology, Internal medicine and Insulin. His work on Type 1 diabetes expands to the thematically related Immunology. His biological study spans a wide range of topics, including Autoantibody, Autoimmune disease, Autoimmunity and SLC30A8.
His Biochemistry research incorporates elements of Molecular biology and Proinsulin. His research integrates issues of Phosphatase and Molecular cloning in his study of Molecular biology. His Endocrinology research incorporates themes from Missense mutation and Compound heterozygosity.
The scientist’s investigation covers issues in Immunology, Biochemistry, Internal medicine, Endocrinology and Molecular biology. His research on Immunology frequently connects to adjacent areas such as Type 1 diabetes. Many of his studies involve connections with topics such as Proinsulin and Biochemistry.
His study in the fields of Insulitis under the domain of Internal medicine overlaps with other disciplines such as Enteroendocrine cell. His research in the fields of Insulin, Islet and Pancreatic islets overlaps with other disciplines such as Pancreatic hormone. His Molecular biology study also includes fields such as
His scientific interests lie mostly in Autoantibody, Type 1 diabetes, Immunology, Diabetes mellitus and Human leukocyte antigen. His Autoantibody research integrates issues from Internal medicine, Endocrinology and SLC30A8. John C. Hutton has researched Endocrinology in several fields, including Interferon gamma and In vivo.
The Type 1 diabetes study combines topics in areas such as CD8 and Genotype. His work on Autoimmunity and Antigen as part of general Immunology research is frequently linked to pernicious anemia, thereby connecting diverse disciplines of science. The various areas that he examines in his Diabetes mellitus study include Insulin and Pediatrics.
John C. Hutton mainly focuses on Autoantibody, Type 1 diabetes, Immunology, Diabetes mellitus and Autoimmunity. The concepts of his Type 1 diabetes study are interwoven with issues in Human leukocyte antigen, Insulin, Disease and Diabetes risk. John C. Hutton has included themes like Molecular biology, Stimulation and Islet in his Immunology study.
His study in Autoimmunity is interdisciplinary in nature, drawing from both Transporter, Beta cell, CD8, Epitope and Cytotoxic T cell. His Zinc Transporter 8 research also covers Endocrinology and Internal medicine studies. His Endocrinology research includes elements of G6PC2 and In vivo.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene
Robert S. Jackson;John W.M. Creemers;Shinya Ohagi;Marie-Laure Raffin-Sanson.
Nature Genetics (1997)
The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes
Janet M. Wenzlau;Kirstine Juhl;Kirstine Juhl;Liping Yu;Ong Moua.
Proceedings of the National Academy of Sciences of the United States of America (2007)
Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice.
Maki Nakayama;Norio Abiru;Hiroaki Moriyama;Naru Babaya.
Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic β cell via two distinct site-specific endopeptidases
Howard W. Davidson;Howard W. Davidson;Christopher J. Rhodes;John C. Hutton.
Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency
Robert S Jackson;John W M Creemers;I Sadaf Farooqi;Marie-Laure Raffin-Sanson.
Journal of Clinical Investigation (2003)
Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes.
Christina Wasmeier;John C. Hutton;John C. Hutton.
Journal of Biological Chemistry (1996)
Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes.
M. S. Hurlbert;Wenbo Zhou;C. Wasmeier;F. G. Kaddis.
T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins
Bart O. Roep;Susan D. Arden;René R. P. de vries;John C. Hutton.
Enterovirus Infection and Progression from Islet Autoimmunity to Type 1 Diabetes: The Diabetes and Autoimmunity Study in the Young (DAISY)
Lars C. Stene;Sami Oikarinen;Heikki Hyöty;Katherine J. Barriga.
A Common Nonsynonymous Single Nucleotide Polymorphism in the SLC30A8 Gene Determines ZnT8 Autoantibody Specificity in Type 1 Diabetes
Janet M. Wenzlau;Yu Liu;Liping Yu;Ong Moua.
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