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Neuroscience

D-Index
40
Citations
8892
World Ranking
7998
National Ranking
370

Overview

Uwe Maskos is affiliated with the Institut Pasteur in France. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Neuroscience, and Medicine. Within these areas, Maskos has contributed notably to subfields including Molecular Biology, Cellular and Molecular Neuroscience, Physiology, Pulmonary and Respiratory Medicine, and Radiology, Nuclear Medicine and Imaging.

Their research focuses extensively on nicotinic acetylcholine receptors, receptor mechanisms and signaling, and the influence of neurotransmitter receptors on behavior. Additional topics include chronic obstructive pulmonary disease (COPD) research, smoking behavior and cessation, neuroscience and neuropharmacology research, and pluripotent stem cells research.

The scientist has published in several prominent venues, with frequent contributions to bioRxiv (Cold Spring Harbor Laboratory), Translational Psychiatry, Nature Communications, Revue des Maladies Respiratoires, and Neuron.

Among recent papers authored or co-authored by Maskos are the following:

  • Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety, 2021, Neuron
  • The Role of the Non-neuronal Cholinergic System in Inflammation and Degradation Processes in Osteoarthritis, 2020, Arthritis & Rheumatology
  • The nicotinic receptor alpha5 coding polymorphism rs16969968 as a major target in disease: Functional dissection and remaining challenges, 2020, Journal of Neurochemistry
  • Nicotinic Receptor Subunits Atlas in the Adult Human Lung, 2020, International Journal of Molecular Sciences
  • Genetic susceptibility to nicotine addiction: Advances and shortcomings in our understanding of the CHRNA5/A3/B4 gene cluster contribution, 2020, Neuropharmacology

Collaborations have been significant in Maskos's work, with frequent co-authors including:

  • Stéphanie Pons (16 publications)
  • Valérian Dormoy (11 publications)
  • Philippe Gosset (9 publications)
  • Fabio Marti (8 publications)
  • Gaëtan Deslée (8 publications)

Their work addresses mechanisms underlying receptor function and genetic polymorphisms related to nicotinic receptors, which play a role in a range of conditions from anxiety modulation to osteoarthritis inflammation and nicotine addiction susceptibility.

Best Publications

  • Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors.

    U. Maskos;B. E. Molles;S. Pons;M. Besson;M. Besson

  • Crucial Role of α4 and α6 Nicotinic Acetylcholine Receptor Subunits from Ventral Tegmental Area in Systemic Nicotine Self-Administration

    S. Pons;L. Fattore;G. Cossu;S. Tolu

  • Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment

    Sylvia Lombardo;Sylvia Lombardo;Uwe Maskos

  • Aversion to Nicotine Is Regulated by the Balanced Activity of β4 and α5 Nicotinic Receptor Subunits in the Medial Habenula

    Silke Frahm;Marta A. Ślimak;Leiron Ferrarese;Julio Santos-Torres

  • Hierarchical Control of Dopamine Neuron-Firing Patterns by Nicotinic Receptors

    Monica Mameli-Engvall;Alexis Evrard;Stéphanie Pons;Uwe Maskos

  • Host-guided migration allows targeted introduction of neurons into the embryonic brain

    Oliver Brüstle;Uwe Maskos;Ronald D.G. McKay

  • Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures

    N. Moser;N. Mechawar;I. Jones;A. Gochberg-Sarver

  • Nicotinic acetylcholine receptor β2-subunits in the medial prefrontal cortex control attention

    Karine Guillem;Bernard Bloem;Rogier B. Poorthuis;Maarten Loos

  • Nicotine reverses hypofrontality in animal models of addiction and schizophrenia

    Fani Koukouli;Marie Rooy;Dimitrios Tziotis;Kurt A. Sailor

  • Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement

    S. Tolu;S. Tolu;R. Eddine;F. Marti;V. David

  • Distinct contributions of nicotinic acetylcholine receptor subunit α4 and subunit α6 to the reinforcing effects of nicotine

    Richard Exley;Nicolas Maubourguet;Vincent David;Raphaël Eddine

  • The cholinergic mesopontine tegmentum is a relatively neglected nicotinic master modulator of the dopaminergic system: relevance to drugs of abuse and pathology.

    U Maskos

  • Nicotinic Acetylcholine Receptors: From Molecular Biology to Cognition

    Jean-Pierre Changeux;Pierre-Jean Corringer;Uwe Maskos

  • Retrograde trans-synaptic transfer of green fluorescent protein allows the genetic mapping of neuronal circuits in transgenic mice

    Uwe Maskos;Karima Kissa;Cécile St. Cloment;Philippe Brûlet

  • Striatal α5 Nicotinic Receptor Subunit Regulates Dopamine Transmission in Dorsal Striatum

    R Exley;J M McIntosh;M J Marks;U Maskos

  • Nicotine consumption is regulated by a human polymorphism in dopamine neurons

    C. Morel;L. Fattore;Stéphanie Pons;Y. A. Hay

  • Neuroprotection of midbrain dopamine neurons by nicotine is gated by cytoplasmic Ca2

    Damien Toulorge;Damien Toulorge;Serge Guerreiro;Serge Guerreiro;Audrey Hild;Audrey Hild;Uwe Maskos

  • Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets.

    Tengfei Li;Matthias Vandesquille;Fani Koukouli;Clémence Dudeffant

  • Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety.

    Claire Nguyen;Sarah Mondoloni;Tinaïg Le Borgne;Ines Centeno

  • Prefrontal nicotinic receptors control novel social interaction between mice

    Maria Elena Avale;Jonathan Chabout;Stéphanie Pons;Pierre Serreau

  • Peroxisome Proliferator-Activated Receptors-Alpha Modulate Dopamine Cell Activity Through Nicotinic Receptors

    Miriam Melis;Stefano Carta;Liana Fattore;Stefania Tolu

  • Live imaging of neural structure and function by fibred fluorescence microscopy

    Pierre Vincent;Pierre Vincent;Uwe Maskos;Igor Charvet;Laurence Bourgeais;Laurence Bourgeais

Frequent Co-Authors

Jean-Pierre Changeux
Jean-Pierre Changeux Institut Pasteur
Boris Gutkin
Boris Gutkin École Normale Supérieure
Alain M. Gardier
Alain M. Gardier University of Paris-Saclay
Michele Zoli
Michele Zoli University of Modena and Reggio Emilia
Salah El Mestikawy
Salah El Mestikawy Douglas Mental Health University Institute
Marc Dhenain
Marc Dhenain University of Paris-Saclay
Jean-Philippe Guilloux
Jean-Philippe Guilloux University of Paris-Saclay
Patricia Robledo
Patricia Robledo Institut Hospital del Mar d'Investigacions Mèdiques
Richard H. Kramer
Richard H. Kramer University of California, Berkeley
Liana Fattore
Liana Fattore National Research Council (CNR)

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