World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
73
Citations
25076
World Ranking
1262
National Ranking
647

Research.com Recognitions

  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jane Y. Wu is affiliated with Northwestern University in the United States and focuses on research primarily within Biochemistry, Genetics, and Molecular Biology. Their scholarly work spans a range of subfields including Molecular Biology, Computer Vision and Pattern Recognition, Biophysics, Computational Mechanics, and Neurology.

The scientist's contributions emphasize topics such as Spectroscopy Techniques in Biomedical and Chemical Research, Spectroscopy and Chemometric Analyses, Metabolomics and Mass Spectrometry Studies, 3D Shape Modeling and Analysis, Amyotrophic Lateral Sclerosis Research, RNA Research and Splicing, and Computer Graphics and Visualization Techniques.

Among their recent publications are:

  • Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis, 2020, Journal of Medicinal Chemistry
  • Characterisation of PDGF-BB:PDGFRβ signalling pathways in human brain pericytes: evidence of disruption in Alzheimer's disease, 2022, Communications Biology
  • Super-resolution SRS microscopy with A-PoD, 2023, Nature Methods
  • SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling, 2020, Nature Communications
  • MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking, 2021, EMBO Reports

Frequent co-authors collaborating with Jane Y. Wu include Lingyan Shi, Anthony A. Fung, Hongje Jang, Dorota Skowronska-Krawczyk, and Richard L. M. Faull.

Their research appears across a variety of publication venues, with frequent contributions in arXiv (Cornell University), bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Protein & Cell, and Agriculture.

Jane Y. Wu was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2011.

Best Publications

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

  • Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

    Jane Y. Wu;Tom Maniatis

  • Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.

    Kit Wong;Xiu Rong Ren;Yang Zhong Huang;Yi Xie

  • Directional guidance of neuronal migration in the olfactory system by the protein Slit.

    Wei Wu;Kit Wong;Jin-hui Chen;Zhi-hong Jiang

  • Vertebrate Slit, a Secreted Ligand for the Transmembrane Protein Roundabout, Is a Repellent for Olfactory Bulb Axons

    Hua shun Li;Jin hui Chen;Wei Wu;Tanya Fagaly

  • Cytoplasmic Mislocalization of TDP-43 Is Toxic to Neurons and Enhanced by a Mutation Associated with Familial Amyotrophic Lateral Sclerosis

    Sami J. Barmada;Gaia Skibinski;Erica Korb;Elizabeth J. Rao

  • The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors.

    Jane Y. Wu;Lili Feng;Hwan Tae Park;Necat Havlioglu

  • Robo4 is a vascular-specific receptor that inhibits endothelial migration

    Kye Won Park;Clayton M. Morrison;Lise K. Sorensen;Christopher A. Jones

  • A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate

    Hua Shun Li;Christopher Tierney;Leng Wen;Jane Y. Wu

  • Cellular and Molecular Guidance of GABAergic Neuronal Migration from an Extracortical Origin to the Neocortex

    Yan Zhu;Hua Shun Li;Lijuan Zhou;Jane Y. Wu

  • An ALS-associated Mutation Affecting TDP-43 Enhances Protein Aggregation, Fibril Formation and Neurotoxicity

    Weirui Guo;Yanbo Chen;Xiaohong Zhou;Amar Kar;Amar Kar

  • A Drosophila model for TDP-43 proteinopathy

    Yan Li;Payal Ray;Elizabeth J. Rao;Chen Shi;Chen Shi

  • Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons.

    Yan Zhu;Tao Yu;Xiao Chun Zhang;Takashi Nagasawa

  • Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction

    Guofa Liu;Hilary Beggs;Claudia Jürgensen;Hwan Tae Park

  • The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance.

    Wenlin Yuan;Lijuan Zhou;Jin hui Chen;Jane Y. Wu

  • New Neurons Clear the Path of Astrocytic Processes for Their Rapid Migration in the Adult Brain

    Naoko Kaneko;Oscar Marín;Masato Koike;Yuki Hirota

  • Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes

    Kit Wong;Hwan Tae Park;Jane Y Wu;Yi Rao

  • Evidence for a physical interaction between presenilin and Notch.

    William J. Ray;Min Yao;Petra Nowotny;Jeff Mumm

  • TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

    Peng Wang;Jianwen Deng;Jie Dong;Jianghong Liu

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

Frequent Co-Authors

Yi Rao
Yi Rao Peking University
Alison Goate
Alison Goate Icahn School of Medicine at Mount Sinai
M.-Marsel Mesulam
M.-Marsel Mesulam Northwestern University
Douglas A. Levine
Douglas A. Levine New York University
Zihe Rao
Zihe Rao Tsinghua University
Jin Chen
Jin Chen Vanderbilt University
Lei Wang
Lei Wang Northwestern University
Jinghui Zhang
Jinghui Zhang St. Jude Children's Research Hospital
Joe W. Gray
Joe W. Gray Oregon Health & Science University
Yanlian Yang
Yanlian Yang University of Chinese Academy of Sciences

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