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Flávia Carvalho Alcantara Gomes

Flávia Carvalho Alcantara Gomes

D-Index & Metrics

Neuroscience

D-Index
44
Citations
5675
World Ranking
7257
National Ranking
59

Overview

Flávia Carvalho Alcantara Gomes is affiliated with the Federal University of Rio de Janeiro in Brazil. Their research spans several interrelated fields including Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology. Within these disciplines, their work notably focuses on Molecular Biology, Neurology, Physiology, Cellular and Molecular Neuroscience, and Developmental Neuroscience.

Their research interests encompass key topics such as Neuroinflammation and Neurodegeneration Mechanisms, Telomeres, Telomerase, and Senescence, Neurogenesis and Neuroplasticity Mechanisms, Alzheimer's Disease Research and Treatments, Histone Deacetylase Inhibitors Research, Multiple Sclerosis Research Studies, and broader Neuroscience and Neuropharmacology Research.

Flávia Carvalho Alcantara Gomes has contributed to scientific literature published in various academic venues. Frequent publication outlets include Aging Cell, Neural Regeneration Research, bioRxiv (Cold Spring Harbor Laboratory), Brain Behavior & Immunity - Health, and Antioxidants.

Notable recent papers include:

  • Loss of lamin-B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus (2021, Aging Cell)
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and glial cells: Insights and perspectives (2020, Brain Behavior & Immunity - Health)
  • Contribution of Müller Cells in the Diabetic Retinopathy Development: Focus on Oxidative Stress and Inflammation (2022, Antioxidants)
  • Central nervous system demyelinating diseases: glial cells at the hub of pathology (2023, Frontiers in Immunology)
  • Age-Associated Upregulation of Glutamate Transporters and Glutamine Synthetase in Senescent Astrocytes In Vitro and in the Mouse and Human Hippocampus (2023, ASN NEURO)

The scientist collaborates regularly with a core group of co-authors including Luan Pereira Diniz, Ana Paula Bérgamo Araújo, Isadora Matias, Gabriele Vargas, and Pedro de Sena Murteira Pinheiro.

Best Publications

  • Astrocyte Heterogeneity: Impact to Brain Aging and Disease.

    Isadora Matias;Juliana Morgado;Flávia Carvalho Alcantara Gomes

  • Glial fibrillary acidic protein (GFAP): modulation by growth factors and its implication in astrocyte differentiation

    F.C.A. Gomes;D. Paulin;V. Moura Neto

  • Astrocyte-induced Synaptogenesis Is Mediated by Transforming Growth Factor β Signaling through Modulation of d-Serine Levels in Cerebral Cortex Neurons

    Luan Pereira Diniz;Juliana Carvalho Almeida;Vanessa Tortelli;Charles Vargas Lopes

  • Emerging roles for TGF-β1 in nervous system development

    Flávia Carvalho Alcantara Gomes;Vivian de Oliveira Sousa;Luciana Romão

  • Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model

    Luan Pereira Diniz;Vanessa Tortelli;Isadora Matias;Juliana Morgado

  • Astrocytes and the TGF-β1 Pathway in the Healthy and Diseased Brain: a Double-Edged Sword.

    Luan Pereira Diniz;Isadora Matias;Michele Siqueira;Joice Stipursky

  • Cognitive dysfunction is sustained after rescue therapy in experimental cerebral malaria, and is reduced by additive antioxidant therapy.

    Patricia A. Reis;Clarissa M. Comim;Fernanda Hermani;Bruno Silva

  • Activated Microglia-Induced Deficits in Excitatory Synapses Through IL-1β: Implications for Cognitive Impairment in Sepsis.

    Carolina A. Moraes;Carolina A. Moraes;Gabriel Santos;Tania Cristina Leite de Sampaio e Spohr;Joana C. D’Avila

  • Neuritogenesis induced by thyroid hormone-treated astrocytes is mediated by epidermal growth factor/mitogen-activated protein kinase-phosphatidylinositol 3-kinase pathways and involves modulation of extracellular matrix proteins.

    Rodrigo Martinez;Flávia Carvalho Alcantara Gomes

  • Astrocyte transforming growth factor beta 1 promotes inhibitory synapse formation via CaM kinase II signaling.

    Luan Pereira Diniz;Vanessa Tortelli;Matheus Nunes Garcia;Ana Paula Bérgamo Araújo

  • TGF-beta1/SMAD signaling induces astrocyte fate commitment in vitro: implications for radial glia development.

    Joice Stipursky;Flávia Carvalho Alcantara Gomes

  • Cerebellar astrocytes treated by thyroid hormone modulate neuronal proliferation.

    Flávia Carvalho Alcantara Gomes;Cecilia Garcia Maia;João Ricardo Lacerda De Menezes;Vivaldo Moura Neto

  • Contribution of Müller Cells in the Diabetic Retinopathy Development: Focus on Oxidative Stress and Inflammation

    Unknown

  • Structure of laminin substrate modulates cellular signaling for neuritogenesis

    Elisabete Freire;Flávia C. A. Gomes;Rafael Linden;Vivaldo Moura Neto

  • Astrocytic control of neural circuit formation: highlights on TGF-beta signaling.

    Luan Pereira Diniz;Isadora C. Pereira Matias;Matheus Nunes Garcia;Flávia Carvalho Alcantara Gomes

  • Neuro–glia interaction effects on GFAP gene: a novel role for transforming growth factor-β1

    Tânia Cristina Leite De Sampaio e Spohr;Rodrigo Martinez;Elen Federowicz Da Silva;Vivaldo Moura Neto

  • Derivation of Functional Human Astrocytes from Cerebral Organoids

    Rômulo Sperduto Dezonne;Rafaela Costa Sartore;Juliana Minardi Nascimento;Verônica M. Saia-Cereda

  • Cross-talk between neurons and glia: highlights on soluble factors

    F.C.A. Gomes;T.C.L.S. Spohr;R. Martinez;V. Moura Neto

  • Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice

    Jordano Brito-Moreira;Mychael V. Lourenco;Mauricio M. Oliveira;Felipe C. Ribeiro

  • Lysophosphatidic acid receptor-dependent secondary effects via astrocytes promote neuronal differentiation.

    Tânia Cristina de Sampaio e Spohr;Ji Woong Choi;Shannon E. Gardell;Deron R. Herr

  • Glutamate activates GFAP gene promoter from cultured astrocytes through TGF‐β1 pathways

    Luciana Ferreira Romão;Vivian de Oliveira Sousa;Vivaldo Moura Neto;Flávia Carvalho Alcantara Gomes

  • Functions of flavonoids in the central nervous system: Astrocytes as targets for natural compounds

    Isadora Matias;Andrea Schmidt Buosi;Flávia Carvalho Alcantara Gomes

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and glial cells: Insights and perspectives.

    Gabriele Vargas;Luiz Henrique Medeiros Geraldo;Natália Gedeão Salomão;Marciano Viana Paes

Frequent Co-Authors

Fernanda G. De Felice
Fernanda G. De Felice Queen's University
Sergio T. Ferreira
Sergio T. Ferreira Federal University of Rio de Janeiro
Stevens K. Rehen
Stevens K. Rehen Federal University of Rio de Janeiro
William L. Klein
William L. Klein Northwestern University
Tatiana Barichello
Tatiana Barichello The University of Texas Health Science Center at Houston
Jerold Chun
Jerold Chun Sanford Burnham Prebys Medical Discovery Institute

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