Neil Upton

Neil Upton publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Neil Upton sits on this spectrum.

Neil Upton D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Neil Upton sits on this spectrum.

Best Publications

• Orexin A activates locus coeruleus cell firing and increases arousal in the rat

  J.J. Hagan;R.A. Leslie;S. Patel;M.L. Evans

  1419
  Citations

• SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist.

  G.A. Kennett;M.D. Wood;F. Bright;B. Trail

  786
  Citations

• The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats.

  David C. Piper;Neil Upton;Martin I. Smith;A. Jackie Hunter

  513
  Citations

• GSK189254, a Novel H3 Receptor Antagonist That Binds to Histamine H3 Receptors in Alzheimer's Disease Brain and Improves Cognitive Performance in Preclinical Models

  Andrew D. Medhurst;Alan R. Atkins;Isabel J. Beresford;Kim Brackenborough

  421
  Citations

• Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonist

  Jim J Hagan;Gary W Price;Phillip Jeffrey;Nigel J Deeks

  348
  Citations

• Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice.

  Haydn M. Prosser;Catherine H. Gill;Warren D. Hirst;Evelyn Grau

  333
  Citations

• SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.

  Warren D. Hirst;Tania O. Stean;Derek C. Rogers;David Sunter

  312
  Citations

• 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease.

  Neil Upton;Tsu Tshen Chuang;Ann J. Hunter;David J. Virley

  308
  Citations

• SB-334867, a selective orexin-1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin-A in rats

  R. J. Rodgers;J. C. G. Halford;R. L. Nunes de Souza;A. L. Canto de Souza

  286
  Citations

• Characterization of SB-271046 : A potent, selective and orally active 5-HT6 receptor antagonist

  Carol Routledge;Steven M Bromidge;Stephen F Moss;Gary W Price

  212
  Citations

• BACE1 (β-secretase) transgenic and knockout mice: identification of neurochemical deficits and behavioral changes

  Steve M Harrison;Alex J Harper;Julie Hawkins;Graham Duddy

  211
  Citations

• Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease

  Perdita L. Pugh;Jill C. Richardson;Simon T. Bate;Neil Upton

  183
  Citations

• The 5-HT 6 Receptor Antagonist SB-271046 Reverses Scopolamine-Disrupted Consolidation of a Passive Avoidance Task and Ameliorates Spatial Task Deficits in Aged Rats

  Andrew G Foley;Keith J Murphy;Warren D Hirst;Helen C Gallagher

  162
  Citations

• A simultaneous ERP/fMRI investigation of the P300 aging effect

  Redmond G. O'Connell;Joshua H. Balsters;Sophia M. Kilcullen;William Campbell

  161
  Citations

• The PPARγ agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B

  L P Quinn;B Crook;M E Hows;M Vidgeon-Hart

  143
  Citations

• GABAB receptor isoforms GBR1a and GBR1b, appear to be associated with pre- and post-synaptic elements respectively in rat and human cerebellum

  Andrew Billinton;Neil Upton;Norman G Bowery

  142
  Citations

• (R)-3,N-dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl) propyl]benzenesulfonamide: the first selective 5-HT7 receptor antagonist.

  Forbes It;Dabbs S;Duckworth Dm;Jennings Aj

  139
  Citations

• Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity.

  D N Jones;J Gartlon;F Parker;S G Taylor

  134
  Citations

• Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX1) receptors, with downstream 5-HT2C receptor involvement.

  Mark S. Duxon;Jennifer Stretton;Kathryn Starr;Declan N.C. Jones

  132
  Citations

• Circadian and dark-pulse activation of orexin/hypocretin neurons

  Oliver J Marston;Rhîannan H Williams;Maria M Canal;Rayna E Samuels

  128
  Citations

• Pittsburgh compound B (11C-PIB) and fluorodeoxyglucose (18 F-FDG) PET in patients with Alzheimer disease, mild cognitive impairment, and healthy controls.

  D.P. Devanand;Arthur Mikhno;Gregory H. Pelton;Katrina Cuasay

  125
  Citations

• Evidence implicating a role for orexin-1 receptor modulation of paradoxical sleep in the rat

  M.I Smith;D.C Piper;M.S Duxon;N Upton

  119
  Citations