Jim J. Hagan

Best Publications

• Orexin A activates locus coeruleus cell firing and increases arousal in the rat

  J.J. Hagan;R.A. Leslie;S. Patel;M.L. Evans

  1419
  Citations

• Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A.

  Reavill C;Taylor Sg;Wood;Ashmeade T

  354
  Citations

• Drug repositioning for Alzheimer's disease

  Anne Corbett;James Pickett;Alistair Burns;Jonathan Corcoran

  351
  Citations

• Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonist

  Jim J Hagan;Gary W Price;Phillip Jeffrey;Nigel J Deeks

  348
  Citations

• The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence.

  Christian A. Heidbreder;Eliot L. Gardner;Zheng-Xiong Xi;Panayotis K. Thanos

  344
  Citations

• Dopamine D3 Receptor Antagonism Inhibits Cocaine-Seeking and Cocaine-Enhanced Brain Reward in Rats

  Stanislav R. Vorel;Charles R. Ashby;Mousumi Paul;Xinhe Liu

  343
  Citations

• Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains.

  Derek C. Rogers;Declan N.C. Jones;Paul R. Nelson;C.Matthew Jones

  335
  Citations

• The Cholinergic Hypothesis of Memory: A Review of Animal Experiments

  J. J. Hagan;R. G. M. Morris

  259
  Citations

• 5-HT7 receptors.

  David R Thomas;Jim J Hagan

  257
  Citations

• Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function

  P R Maycox;F Kelly;A Taylor;S Bates

  239
  Citations

• Long-lasting changes in behavioural and neuroendocrine indices in the rat following neonatal maternal separation: gender-dependent effects.

  Helge A. Slotten;Mikhail Kalinichev;Jim J. Hagan;Charles A. Marsden

  226
  Citations

• Isolation rearing induces recognition memory deficits accompanied by cytoskeletal alterations in rat hippocampus

  M. Bianchi;M. Bianchi;K. F C Fone;Norazrina Azmi;C. A. Heidbreder

  223
  Citations

• Attenuation of cue-controlled cocaine-seeking by a selective D3 dopamine receptor antagonist SB-277011-A.

  Patricia Di Ciano;Rachel J Underwood;Jim J Hagan;Barry J Everitt

  214
  Citations

• 5-HT6 receptor antagonist SB-271046 enhances extracellular levels of monoamines in the rat medial prefrontal cortex.

  Laurent P. Lacroix;Lee A. Dawson;Jim J. Hagan;Christian A. Heidbreder

  213
  Citations

• Blockade of mesolimbic dopamine D3 receptors inhibits stress-induced reinstatement of cocaine-seeking in rats.

  Zheng-Xiong Xi;Jeremy Gilbert;Arlene C. Campos;Nicole Kline

  204
  Citations

• Selective antagonism at dopamine D3 receptors prevents nicotine-triggered relapse to nicotine-seeking behavior.

  Michela Andreoli;Michela Tessari;Maria Pilla;Enzo Valerio

  202
  Citations

• Blockade of spatial learning by the M1 muscarinic antagonist pirenzepine.

  J. J. Hagan;J. H. M. Jansen;C. L. E. Broekkamp

  201
  Citations

• Design and Synthesis of trans-N-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat

  Geoffrey Stemp;Tracey Ashmeade;Clive L. Branch;Michael S. Hadley

  192
  Citations

• Behavioral screening for cognition enhancers: from indiscriminate to valid testing: Part I

  Martin Sarter;Jim Hagan;Paul Dudchenko

  187
  Citations

• SB-656104-A, a novel selective 5-HT7 receptor antagonist, modulates REM sleep in rats

  David R Thomas;Sergio Melotto;Mario Massagrande;Andrew D Gribble

  175
  Citations