Claudia Schoch

Overview

Best Publications

• Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease.

  Susanne Schnittger;Claudia Schoch;Martin Dugas;Wolfgang Kern

  1438
  Citations

• Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy.

  A. Hochhaus;S. Kreil;A. S. Corbin;P. La Rosée;P. La Rosée

  1210
  Citations

• Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype

  Susanne Schnittger;Claudia Schoch;Wolfgang Kern;Cristina Mecucci

  908
  Citations

• AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

  Thomas Pabst;Beatrice U. Mueller;Nari Harakawa;Claudia Schoch

  596
  Citations

• KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival

  Susanne Schnittger;Tobias M. Kohl;Torsten Haferlach;Wolfgang Kern

  512
  Citations

• Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group.

  Thomas Büchner;Wolfgang Hiddemann;Bernhard Wörmann;Helmut Löffler

  495
  Citations

• AML with 11q23/MLL abnormalities as defined by the WHO classification: incidence, partner chromosomes, FAB subtype, age distribution, and prognostic impact in an unselected series of 1897 cytogenetically analyzed AML cases

  Claudia Schoch;Susanne Schnittger;Mirjam Klaus;Wolfgang Kern

  443
  Citations

• Diversity and Functional Consequences of Germline and Somatic PTPN11 Mutations in Human Disease

  Marco Tartaglia;Simone Martinelli;Lorenzo Stella;Gianfranco Bocchinfuso

  435
  Citations

• Comparison of chromosome banding analysis, interphase- and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: a study on 350 cases

  C Schoch;S Schnittger;S Bursch;D Gerstner

  419
  Citations

• Implications of NRAS mutations in AML: a study of 2502 patients.

  Ulrike Bacher;Torsten Haferlach;Claudia Schoch;Wolfgang Kern

  408
  Citations

• Screening for MLL tandem duplication in 387 unselected patients with AML identify a prognostically unfavorable subset of AML

  S Schnittger;U Kinkelin;C Schoch;A Heinecke

  406
  Citations

• Early blast clearance by remission induction therapy is a major independent prognostic factor for both achievement of complete remission and long-term outcome in acute myeloid leukemia: data from the German AML Cooperative Group (AMLCG) 1992 Trial

  Wolfgang Kern;Torsten Haferlach;Claudia Schoch;Helmut Löffler

  398
  Citations

• Karyotype is an independent prognostic parameter in therapy-related acute myeloid leukemia (t-AML): an analysis of 93 patients with t-AML in comparison to 1091 patients with de novo AML.

  C Schoch;W Kern;S Schnittger;W Hiddemann

  392
  Citations

• The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2

  Andreas Reiter;Christoph Walz;Ann Watmore;Claudia Schoch

  347
  Citations

• Determination of relapse risk based on assessment of minimal residual disease during complete remission by multiparameter flow cytometry in unselected patients with acute myeloid leukemia.

  Wolfgang Kern;Daniela Voskova;Claudia Schoch;Wolfgang Hiddemann

  346
  Citations

• Management of Acute Myeloid Leukemia in Elderly Patients

  Wolfgang Hiddemann;Wolfgang Kern;Claudia Schoch;Christa Fonatsch

  335
  Citations

• Acute myeloid leukemias with reciprocal rearrangements can be distinguished by specific gene expression profiles.

  Claudia Schoch;Alexander Kohlmann;Alexander Kohlmann;Susanne Schnittger;Susanne Schnittger;Benedikt Brors;Benedikt Brors

  329
  Citations

• The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia.

  Rajani K. Vangala;Marion S. Heiss-Neumann;Marion S. Heiss-Neumann;Janki S. Rangatia;Janki S. Rangatia;Sheo M. Singh;Sheo M. Singh

  312
  Citations

• Global approach to the diagnosis of leukemia using gene expression profiling.

  Torsten Haferlach;Alexander Kohlmann;Susanne Schnittger;Martin Dugas

  298
  Citations

• The MLL recombinome of acute leukemias.

  C. Meyer;B. Schneider;S. Jakob;S. Strehl

  280
  Citations