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Stefano Confalonieri

Stefano Confalonieri

D-Index & Metrics

Molecular Biology

D-Index
45
Citations
8980
World Ranking
2854
National Ranking
70

Overview

Stefano Confalonieri is affiliated with the European Institute of Oncology in Italy. Their research spans various fields within biochemistry, genetics, molecular biology, and medicine, with particular focus on molecular biology, oncology, cell biology, cancer research, and biotechnology.

The scientist's published work has appeared in several peer-reviewed journals, notably including:

  • Cell Reports
  • Advanced Science
  • Nature Communications
  • Cell Death and Disease
  • Cancers

Key research topics explored by Confalonieri include:

  • Ubiquitin and proteasome pathways
  • Epigenetics and DNA methylation
  • Cellular transport and secretion
  • Cancer cells and metastasis
  • Cancer, hypoxia, and metabolism
  • Histone deacetylase inhibitors research
  • Glycosylation and glycoproteins research

Recent papers authored or co-authored by Confalonieri demonstrate a focus on cellular and molecular mechanisms related to cancer biology and neurobiology, including:

  • "Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors," 2022, Cell Reports
  • "A self-sustaining endocytic-based loop promotes breast cancer plasticity leading to aggressiveness and pro-metastatic behavior," 2020, Nature Communications
  • "ShcD Binds DOCK4, Promotes Ameboid Motility and Metastasis Dissemination, Predicting Poor Prognosis in Melanoma," 2020, Cancers
  • "TBC1 domain-containing proteins are frequently involved in triple-negative breast cancers in connection with the induction of a glycolytic phenotype," 2024, Cell Death and Disease
  • "Zebrafish dnm1a gene plays a role in the formation of axons and synapses in the nervous tissue," 2023, Journal of Neuroscience Research

Frequent collaborators include:

  • Pier Paolo Di Fiore
  • Giovanni Bertalot
  • Stefano Freddi
  • Daniela Tosoni
  • Salvatore Pece

Best Publications

  • Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content.

    Salvatore Pece;Daniela Tosoni;Stefano Confalonieri;Giovanni Mazzarol

  • Binding specificity and in vivo targets of the EH domain, a novel protein–protein interaction module

    Anna Elisabetta Salcini;Stefano Confalonieri;Margherita Doria;Elisa Santolini

  • Endocytosis and signaling: cell logistics shape the eukaryotic cell plan.

    Sara Sigismund;Stefano Confalonieri;Andrea Ciliberto;Simona Polo

  • Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response

    Chiara Gorrini;Massimo Squatrito;Massimo Squatrito;Chiara Luise;Nelofer Syed

  • Regulation of actin dynamics by WASP and WAVE family proteins.

    Theresia E.B. Stradal;Klemens Rottner;Andrea Disanza;Stefano Confalonieri

  • Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin.

    Lorenza Penengo;Marina Mapelli;Andrea G. Murachelli;Stefano Confalonieri

  • IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions

    Giorgio Scita;Stefano Confalonieri;Pekka Lappalainen;Shiro Suetsugu

  • Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop.

    Nicola Aceto;Nina Sausgruber;Heike Brinkhaus;Dimos Gaidatzis

  • Evolution of Shc functions from nematode to human.

    Lucilla Luzi;Stefano Confalonieri;Pier Paolo Di Fiore;Pier Giuseppe Pelicci

  • Molecular mechanisms of coupled monoubiquitination

    Tanja Woelk;Barbara Oldrini;Elena Maspero;Stefano Confalonieri

  • Eps8 controls actin-based motility by capping the barbed ends of actin filaments

    Andrea Disanza;Marie-France Carlier;Theresia E. B. Stradal;Dominique Didry

  • Frequent alterations in the expression of serine/threonine kinases in human cancers

    Maria Capra;Paolo Giovanni Nuciforo;Stefano Confalonieri;Micaela Quarto

  • NUMB-ing down cancer by more than just a NOTCH

    Salvatore Pece;Stefano Confalonieri;Pascale R. Romano;Pier Paolo Di Fiore

  • Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis.

    Stefano Confalonieri;Anna Elisabetta Salcini;Claudia Puri;Carlo Tacchetti

  • Alterations of ubiquitin ligases in human cancer and their association with the natural history of the tumor.

    S Confalonieri;M Quarto;G Goisis;P Nuciforo

  • Determinants of conformational dimerization of Mad2 and its inhibition by p31comet

    Marina Mapelli;Fabian V Filipp;Giulia Rancati;Lucia Massimiliano

  • Breast cancer metastases are molecularly distinct from their primary tumors.

    M Vecchi;S Confalonieri;P Nuciforo;M A Viganò

  • Recognition specificity of individual EH domains of mammals and yeast

    Serena Paoluzi;Luisa Castagnoli;Ilde Lauro;Anna Elisabetta Salcini

  • Eps15 Is Recruited to the Plasma Membrane upon Epidermal Growth Factor Receptor Activation and Localizes to Components of the Endocytic Pathway during Receptor Internalization

    Maria Rosaria Torrisi;Lavinia Vittoria Lotti;Francesca Belleudi;Roberto Gradini

  • A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination

    Emanuela Frittoli;Andrea Palamidessi;Paola Marighetti;Stefano Confalonieri

Frequent Co-Authors

Pier Paolo Di Fiore
Pier Paolo Di Fiore University of Milan
Giuseppe Viale
Giuseppe Viale University of Milan
Giorgio Scita
Giorgio Scita FIRC Institute of Molecular Oncology
Pier Giuseppe Pelicci
Pier Giuseppe Pelicci European Institute of Oncology
Elisabetta Dejana
Elisabetta Dejana Uppsala University
Simona Polo
Simona Polo University of Milan
Carlo Tacchetti
Carlo Tacchetti Vita-Salute San Raffaele University
Philippe Chavrier
Philippe Chavrier Institute Curie
Andrea Doni
Andrea Doni Humanitas Research Hospital
Melitta Schachner
Melitta Schachner Rutgers, The State University of New Jersey

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