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Yoshiharu Iwabuchi

Yoshiharu Iwabuchi

D-Index & Metrics

Chemistry

D-Index
50
Citations
9215
World Ranking
14355
National Ranking
1117

Overview

Yoshiharu Iwabuchi is affiliated with Tohoku University in Japan, focusing extensively on research within the field of Chemistry, particularly Organic Chemistry. Their work spans several subfields including Organic Chemistry, Molecular Biology, Pharmacology, Electrochemistry, and Electrical and Electronic Engineering, with a significant volume of publications in Organic Chemistry.

Their research covers multiple main topics, prominently including Oxidative Organic Chemistry Reactions, Radical Photochemical Reactions, Synthetic Organic Chemistry Methods, Asymmetric Synthesis and Catalysis, Catalytic C-H Functionalization Methods, Electrochemical Analysis and Applications, and Synthesis and Catalytic Reactions.

Recent publications by Yoshiharu Iwabuchi include:

  • The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice (2020, Scientific Reports)
  • The Curcumin Analog GO-Y030 Controls the Generation and Stability of Regulatory T Cells (2021, Frontiers in Immunology)
  • ortho-C-H Acetoxylation of Cubane Enabling Access to Cubane Analogues of Pharmaceutically Relevant Scaffolds (2021, Organic Letters)
  • Biological Evaluation of Isosteric Applicability of 1,3-Substituted Cuneanes as m-Substituted Benzenes Enabled by Selective Isomerization of 1,4-Substituted Cubanes (2023, Chemistry - A European Journal)
  • Chromium-Salen Complex/Nitroxyl Radical Cooperative Catalysis: A Combination for Aerobic Intramolecular Dearomative Coupling of Phenols (2021, The Journal of Organic Chemistry)

Frequent publication venues for Iwabuchi's research include:

  • Organic Letters
  • The Journal of Organic Chemistry
  • Chemical and Pharmaceutical Bulletin
  • Analytical Sciences
  • Advanced Science

Yoshiharu Iwabuchi maintains collaborative relationships with several coauthors frequently appearing in their publications. These include:

  • Yusuke Sasano
  • Shota Nagasawa
  • Katsuhiko Sato
  • Hiroyuki Yamakoshi
  • Tetsuya Ono

The body of work shows a strong emphasis on synthetic organic chemistry methods and catalytic processes, often in combination with biological or medicinal chemistry applications. This includes studies on curcumin analogues and novel catalytic systems for organic transformation.

Best Publications

  • Chiral Amine-Catalyzed Asymmetric Baylis−Hillman Reaction: A Reliable Route to Highly Enantiomerically Enriched (α-Methylene-β-hydroxy)esters

    Yoshiharu Iwabuchi;Mari Nakatani;Nobiko Yokoyama;Susumi Hatakeyama

  • 2-Azaadamantane N-Oxyl (AZADO) and 1-Me-AZADO: Highly Efficient Organocatalysts for Oxidation of Alcohols

    Masatoshi Shibuya;Masaki Tomizawa;Iwao Suzuki;Yoshiharu Iwabuchi

  • Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer

    Hisatsugu Ohori;Hiroyuki Yamakoshi;Masaki Tomizawa;Masatoshi Shibuya

  • Highly efficient, organocatalytic aerobic alcohol oxidation.

    Masatoshi Shibuya;Yuji Osada;Yusuke Sasano;Masaki Tomizawa

  • Highly Chemoselective Aerobic Oxidation of Amino Alcohols into Amino Carbonyl Compounds

    Yusuke Sasano;Shota Nagasawa;Mai Yamazaki;Masatoshi Shibuya;Masatoshi Shibuya

  • Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030

    Lin L;Liu Y;Li H;Li Pk

  • An enantio- and stereocontrolled synthesis of (−)-mycestericin E via cinchona alkaloid-catalyzed asymmetric Baylis–Hillman reaction

    Yoshiharu Iwabuchi;Mariko Furukawa;Tomoyuki Esumi;Susumi Hatakeyama

  • Total synthesis of calicheamicin .gamma.1I. 1. Synthesis of the oligosaccharide fragment

    R. D. Groneberg;T. Miyazaki;N. A. Stylianides;T. J. Schulze

  • Oxidative Rearrangement of Tertiary Allylic Alcohols Employing Oxoammonium Salts

    Masatoshi Shibuya;Masaki Tomizawa;Yoshiharu Iwabuchi

  • An Expeditious Entry to 9-Azabicyclo[3.3.1]nonane N-Oxyl (ABNO): Another Highly Active Organocatalyst for Oxidation of Alcohols

    Masatoshi Shibuya;Masaki Tomizawa;Yusuke Sasano;Yoshiharu Iwabuchi

  • beta-Isocupreidine-catalyzed asymmetric Baylis-Hillman reaction of imines.

    Unknown

  • Total synthesis of sialyl dimeric Lex

    K. C. Nicolaou;K. C. Nicolaou;C. W. Hummel;C. W. Hummel;Y. Iwabuchi;Y. Iwabuchi

  • Discovery and Exploitation of AZADO: The Highly Active Catalyst for Alcohol Oxidation

    Yoshiharu Iwabuchi

  • Oxoammonium salt/NaClO2: an expedient, catalytic system for one-pot oxidation of primary alcohols to carboxylic acids with broad substrate applicability

    Masatoshi Shibuya;Takahisa Sato;Masaki Tomizawa;Yoshiharu Iwabuchi

  • Organocatalytic Entry to Chiral Bicyclo[3.n.1]alkanones via Direct Asymmetric Intramolecular Aldolization

    Noriaki Itagaki;Mari Kimura;Tsutomu Sugahara;Yoshiharu Iwabuchi

  • An enantio- and stereocontrolled route to epopromycin B via cinchona alkaloid-catalyzed Baylis-Hillman reaction

    Yoshiharu Iwabuchi;Tatsuya Sugihara;Tomoyuki Esumi;Susumi Hatakeyama

  • Evolving catalytic antibodies in a phage-displayed combinatorial library.

    Ikuo Fujii;Shiro Fukuyama;Yoshiharu Iwabuchi;Ryuji Tanimura

  • Highly Enantioselective Organocatalytic Oxidative Kinetic Resolution of Secondary Alcohols Using Chirally Modified AZADOs

    Masaki Tomizawa;Masatoshi Shibuya;Yoshiharu Iwabuchi

  • β-Isocupreidine–hexafluoroisopropyl acrylate method for asymmetric Baylis–Hillman reactions

    Ayako Nakano;Sakie Kawahara;Saori Akamatsu;Kenji Morokuma

  • Potent antimalarial febrifugine analogues against the Plasmodium malaria parasite

    Haruhisa Kikuchi;Hidehisa Tasaka;Shingo Hirai;Yoshiaki Takaya

  • Oxidative rearrangement of cyclic tertiary allylic alcohols with IBX in DMSO.

    Masatoshi Shibuya;Shinichiro Ito;Michiyasu Takahashi;Yoshiharu Iwabuchi

  • Activation of phosphatidylinositol 3-kinase/protein kinase B pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia.

    N. Shioda;T. Ishigami;F. Han;S. Moriguchi

Frequent Co-Authors

Chikashi Ishioka
Chikashi Ishioka Tohoku University
Hideaki Kakeya
Hideaki Kakeya Kyoto University
Kohji Fukunaga
Kohji Fukunaga Tohoku University
Mikiko Sodeoka
Mikiko Sodeoka Sagami Central Chemical Research Institute
Yasushi Ohizumi
Yasushi Ohizumi Tohoku University
Yoshiteru Oshima
Yoshiteru Oshima Tohoku University
Kazuya Yamaguchi
Kazuya Yamaguchi University of Tokyo
Noritaka Mizuno
Noritaka Mizuno University of Tokyo
Suresh V. Ambudkar
Suresh V. Ambudkar National Institutes of Health

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