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Biology and Biochemistry

D-Index
49
Citations
6433
World Ranking
18152
National Ranking
1428

Overview

Janis K. Shute is affiliated with the University of Portsmouth in the United Kingdom. Their research primarily focuses on medicine, with significant contributions to pulmonary and respiratory medicine, physiology, infectious diseases, neurology, and immunology.

The main topics covered in their research include:

  • Asthma and respiratory diseases
  • Cystic Fibrosis Research Advances
  • COVID-19 Clinical Research Studies
  • Respiratory Support and Mechanisms
  • Long-Term Effects of COVID-19
  • Exercise and Physiological Responses
  • Inhalation and Respiratory Drug Delivery

Some of their recent published papers include:

  • "Nebulised heparin as a treatment for COVID-19: scientific rationale and a call for randomised evidence," 2020, Critical Care
  • "Circulating biomarkers of antioxidant status and oxidative stress in people with cystic fibrosis: A systematic review and meta-analysis," 2020, Redox Biology
  • "Heparin, Low Molecular Weight Heparin, and Non-Anticoagulant Derivatives for the Treatment of Inflammatory Lung Disease," 2023, Pharmaceuticals
  • "INHALEd nebulised unfractionated HEParin for the treatment of hospitalised patients with COVID-19 (INHALE-HEP): Protocol and statistical analysis plan for an investigator-initiated international metatrial of randomised studies," 2020, British Journal of Clinical Pharmacology
  • "Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3," 2021, American Journal of Respiratory Cell and Molecular Biology

Shute collaborates frequently with several co-authors, including:

  • Anthony I. Shepherd
  • Zoe L. Saynor
  • Clive Page
  • Michael H. Cummings
  • Jo Corbett

Their work has been published in a variety of journals, with multiple contributions to the following venues:

  • Critical Care
  • Pharmaceuticals
  • Redox Biology
  • British Journal of Clinical Pharmacology
  • American Journal of Respiratory Cell and Molecular Biology

Best Publications

  • Interleukin-8 concentrations are elevated in bronchoalveolar lavage, sputum, and sera of children with cystic fibrosis

    Taraneh P Dean;Yalei Dai;Janis K Shute;Martin K Church

  • MMP-9, TIMP-1 and inflammatory cells in sputum from COPD patients during exacerbation

    PF Mercer;JK Shute;A Bhowmik;GC Donaldson

  • Effect of treatment with dornase alpha on airway inflammation in patients with cystic fibrosis.

    Karl Paul;Ernst Rietschel;Manfred Ballmann;Matthias Griese

  • The purification and properties of myo-inositol monophosphatase from bovine brain

    N S Gee;C I Ragan;K J Watling;S Aspley

  • Plasminogen Activator Inhibitor-1 Supports IL-8-Mediated Neutrophil Transendothelial Migration by Inhibition of the Constitutive Shedding of Endothelial IL-8/Heparan Sulfate/Syndecan-1 Complexes

    Lindsay J. Marshall;Lara S.P. Ramdin;Teresa Brooks;Peter Charlton

  • Airway remodelling in children with cystic fibrosis.

    Tom N Hilliard;Nicolas Regamey;Janis K Shute;Andrew G Nicholson

  • Immunohistochemical localisation of the matrix metalloproteinases MMP-3 and MMP-9 within the airways in asthma

    Barbro Dahlen;Janis Shute;Peter Howarth

  • The inflammatory effects of 2 ppm NO2 on the airways of healthy subjects

    Anders Blomberg;Mamidipudi T. Krishna;Vincenzo Bocchino;Gian Luca Biscione

  • Effects of theophylline and rolipram on leukotriene C4 (LTC4) synthesis and chemotaxis of human eosinophils from normal and atopic subjects.

    Hermann Tenor;Armin Hatzelmann;Martin K. Church;Christian Schudt

  • Alveolar inflammation in cystic fibrosis

    Martina Ulrich;Dieter Worlitzsch;Dieter Worlitzsch;Simona Viglio;Nanna Siegmann

  • RANTES, macrophage-inhibitory protein 1α, and the eosinophil product major basic protein are released into upper respiratory secretions during virus-induced asthma exacerbations in children

    Luis M. Teran;Luis M. Teran;Maria Cristina Seminario;Maria Cristina Seminario;Janis K. Shute;Alberto Papi;Alberto Papi

  • Free and complexed interleukin-8 in blood and bronchial mucosa in asthma

    Janis K. Shute;Bart Vrugt;Ivan J. D. Lindley;Stephen T. Holgate

  • Chemical and kinetic mechanism of the inositol monophosphatase reaction and its inhibition by Li

    Andrew P. Leech;Graham R. Baker;Janis K. Shute;Mark A. Cohen

  • Cyclic nucleotide phosphodiesterase isoenzyme activities in human alveolar macrophages

    H. Tenor;H. Tenor;A. Hatzelmann;R. Kupferschmidt;L. Stanciu

  • The effect of processing on inflammatory markers in induced sputum

    Renaud Louis;J. Shute;K. Goldring;B. Perks

  • Cyclic nucleotide phosphodiesterases from purified human CD4+ and CD8+ T lymphocytes

    H. Tenor;L. Staniciu;C. Schudt;A. Hatzelmann

  • Influence of interleukin-8 challenge in the nasal mucosa in atopic and nonatopic subjects

    Jo A. Douglass;Deepak Dhami;Caroline E. Gurr;Mark Bulpitt

  • Coagulation factors in the airways in moderate and severe asthma and the effect of inhaled steroids

    Fraser J H Brims;Anoop J Chauhan;Bernard R Higgins;Janis K Shute

  • Role of elevated plasma soluble ICAM-1 and bronchial lavage fluid IL-8 levels as markers of chronic lung disease in premature infants

    S. Little;Taraneh Dean;S. Bevin;M. Hall

  • Nebulised heparin as a treatment for COVID-19: scientific rationale and a call for randomised evidence.

    Frank M. P. Van Haren;Frank M. P. Van Haren;Clive Page;John G. Laffey;John G. Laffey;Antonio Artigas

Frequent Co-Authors

Stephen T. Holgate
Stephen T. Holgate University of Southampton
Ratko Djukanovic
Ratko Djukanovic University of Southampton
Clive P. Page
Clive P. Page King's College London
John G. Laffey
John G. Laffey University of Galway
Andrew Bush
Andrew Bush Imperial College London
Jane Warner
Jane Warner University of Southampton
Martin K. Church
Martin K. Church Southampton General Hospital
Peter H. Howarth
Peter H. Howarth University of Southampton
Susan J. Wilson
Susan J. Wilson University of Southampton
Gilberto De Nucci
Gilberto De Nucci Universidade de São Paulo

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