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Immunology

D-Index
45
Citations
13595
World Ranking
4667
National Ranking
397

Overview

Paola Di Meglio is affiliated with King's College London in the United Kingdom. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a focused subfield emphasis on Immunology, Dermatology, Oncology, Clinical Psychology, and Physiology. The core topics of their work revolve around psoriasis, dermatology and skin diseases, asthma and respiratory diseases, cytokine signaling pathways, COVID-19 and mental health, COVID-19 clinical research studies, and immunotherapy and immune responses.

Their published work includes papers in diverse, peer-reviewed journals. Selected recent research includes:

  • Factors associated with adverse COVID-19 outcomes in patients with psoriasis-insights from a global registry-based study, 2020, Journal of Allergy and Clinical Immunology
  • Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function, 2022, Nature Genetics
  • CYP1A1 Enzymatic Activity Influences Skin Inflammation Via Regulation of the AHR Pathway, 2020, Journal of Investigative Dermatology
  • Biomarkers of disease progression in people with psoriasis: a scoping review, 2022, British Journal of Dermatology
  • Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis, 2021, Nature Communications

Paola Di Meglio frequently publishes in specific scientific venues, reflecting the focus of their research interests. These include:

  • British Journal of Dermatology
  • Journal of Investigative Dermatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Allergy and Clinical Immunology

Their research collaboration network is characterized by repeated partnerships with several co-authors, including Juliet N. Barker, Catherine Smith, Nick Dand, Richard B. Warren, and C.E.M. Griffiths.

Best Publications

  • Skin immune sentinels in health and disease

    Frank O. Nestle;Paola Di Meglio;Jian-Zhong Qin;Brian J. Nickoloff

  • The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis

    Antonella Di Cesare;Paola Di Meglio;Frank O. Nestle

  • The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

    Brigitta Stockinger;Paola Di Meglio;Manolis Gialitakis;João H Duarte

  • Mapping cis - and trans -regulatory effects across multiple tissues in twins

    E Grundberg;K S Small;K S Small;Å K Hedman;A C Nica

  • Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis

    Alexandros Onoufriadis;Michael A. Simpson;Andrew E. Pink;Paola Di Meglio

  • Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis

    Francesca Capon;Paola Di Meglio;Joanna Szaub;Natalie J. Prescott

  • The architecture of gene regulatory variation across multiple human tissues: the MuTHER study

    Alexandra C. Nica;Alexandra C. Nica;Leopold Parts;Daniel Glass;James Nisbet

  • The Multitasking Organ: Recent Insights into Skin Immune Function

    Paola Di Meglio;Gayathri K. Perera;Frank O. Nestle

  • Characterization of Innate Lymphoid Cells in Human Skin and Blood Demonstrates Increase of NKp44+ ILC3 in Psoriasis

    Federica Villanova;Federica Villanova;Barry Flutter;Isabella Tosi;Isabella Tosi;Katarzyna Grys;Katarzyna Grys

  • Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions.

    Paola Di Meglio;João H. Duarte;Helena Ahlfors;Nick D.L. Owens

  • Identification of a Novel Proinflammatory Human Skin-Homing Vγ9Vδ2 T Cell Subset with a Potential Role in Psoriasis

    Ute Laggner;Paola Di Meglio;Gayathri K. Perera;Christian Hundhausen

  • The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis

    Mario Roederer;Lydia Quaye;Massimo Mangino;Massimo Mangino;Margaret H. Beddall

  • Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

    Chung-Ching Chu;Niwa Ali;Panagiotis Karagiannis;Paola Di Meglio

  • Gene expression changes with age in skin, adipose tissue, blood and brain.

    Daniel Glass;Daniel Glass;Ana Viñuela;Matthew N Davies;Adaikalavan Ramasamy

  • The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans.

    Paola Di Meglio;Antonella Di Cesare;Antonella Di Cesare;Ute Laggner;Chung-Ching Chu

  • Cutting Edge: A Critical Functional Role for IL-23 in Psoriasis

    Giulia Tonel;Giulia Tonel;Curdin Conrad;Ute Laggner;Paola Di Meglio

  • Factors associated with adverse COVID-19 outcomes in patients with psoriasis-insights from a global registry-based study.

    Satveer K. Mahil;Nick Dand;Kayleigh J. Mason;Zenas Z.N. Yiu

  • Biomarkers in psoriasis and psoriatic arthritis.

    Federica Villanova;Federica Villanova;Paola Di Meglio;Frank O Nestle;Frank O Nestle

  • A Role for Th17 Cells in the Immunopathogenesis of Atopic Dermatitis

    Antonella Di Cesare;Antonella Di Cesare;Paola Di Meglio;Frank O. Nestle

  • The role of IL-23 in the immunopathogenesis of psoriasis.

    Paola Di Meglio;Frank O Nestle

  • HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis

    Nick Dand;Michael Duckworth;David Baudry;Alice Russell

  • The IL-23/Th17 Axis in the Immunopathogenesis of

    Psoriasis Di Cesare;Paola Di Meglio;Frank O. Nestle

Frequent Co-Authors

Frank O. Nestle
Frank O. Nestle Deerfield (United States)
Jonathan Barker
Jonathan Barker King's College London
Catherine Smith
Catherine Smith King's College London
Richard C. Trembath
Richard C. Trembath King's College London
Francesca Capon
Francesca Capon King's College London
Christopher E.M. Griffiths
Christopher E.M. Griffiths University of Manchester
Adrian Hayday
Adrian Hayday King's College London
Brigitta Stockinger
Brigitta Stockinger The Francis Crick Institute
Kerrin S. Small
Kerrin S. Small King's College London

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