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D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
8488
World Ranking
18684
National Ranking
7639

Overview

Brian F. Pfleger is affiliated with the University of Wisconsin-Madison in the United States. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a distinct focus on Molecular Biology as a key subfield. They also contribute to Biomedical Engineering, Industrial and Manufacturing Engineering, Renewable Energy, Sustainability and the Environment, and Plant Science.

Their work addresses several main topics within these fields, including:

  • Microbial Metabolic Engineering and Bioproduction
  • Enzyme Catalysis and Immobilization
  • Biofuel Production and Bioconversion
  • Photosynthetic Processes and Mechanisms
  • Algal Biology and Biofuel Production
  • Plant Biochemistry and Biosynthesis
  • Genomics and Phylogenetic Studies

Brian F. Pfleger has authored numerous scientific papers. Notable recent publications include:

  • A Review of Biodegradable Plastics: Chemistry, Applications, Properties, and Future Research Needs, 2023, Chemical Reviews
  • Machine learning-guided acyl-ACP reductase engineering for improved in vivo fatty alcohol production, 2021, Nature Communications
  • Lignin conversion to β-ketoadipic acid by Pseudomonas putida via metabolic engineering and bioprocess development, 2023, Science Advances
  • Rewiring yeast metabolism to synthesize products beyond ethanol, 2020, Current Opinion in Chemical Biology
  • Recent progress in the synthesis of advanced biofuel and bioproducts, 2023, Current Opinion in Biotechnology

Their work has appeared frequently in several publication venues, including:

  • Metabolic Engineering
  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Synthetic Biology
  • Nature Communications
  • Current Opinion in Chemical Biology

Collaboration is a significant part of their research activity. Frequent coauthors include:

  • William T. Cordell
  • Michael A. Jindra
  • Qiang Yan
  • Daniel Amador-Noguez
  • Joshua P. Abraham

The combination of research topics, fields of study, and publication records indicates a focus on advancing understanding and applications in microbial metabolic pathways, biofuel technologies, and enzyme engineering. Their research contributions are integrated within interdisciplinary domains concerning sustainable bioproduction and biochemical processes.

Best Publications

  • Nonenzymatic Sugar Production from Biomass Using Biomass-Derived γ-Valerolactone

    Jeremy S. Luterbacher;Jacqueline M. Rand;David Martin Alonso;Jeehoon Han

  • Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes

    Brian F Pfleger;Douglas J Pitera;Christina D Smolke;Christina D Smolke;Jay D Keasling;Jay D Keasling

  • Common principles and best practices for engineering microbiomes

    Christopher E. Lawson;William R. Harcombe;Roland Hatzenpichler;Stephen R. Lindemann

  • A process for microbial hydrocarbon synthesis: Overproduction of fatty acids in Escherichia coli and catalytic conversion to alkanes.

    Rebecca M. Lennen;Drew J. Braden;Ryan M. West;James A. Dumesic

  • Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals

    David Jullesson;Florian David;Brian Pfleger;Jens Nielsen

  • Application of Functional Genomics to Pathway Optimization for Increased Isoprenoid Production

    Lance Kizer;Douglas J. Pitera;Brian F. Pfleger;Jay D. Keasling;Jay D. Keasling

  • Microbial production of fatty acid-derived fuels and chemicals

    Rebecca M Lennen;Brian F Pfleger

  • Engineering Escherichia coli to synthesize free fatty acids.

    Rebecca M. Lennen;Brian F. Pfleger;Brian F. Pfleger

  • Synthetic Biology Toolbox for Controlling Gene Expression in the Cyanobacterium Synechococcus sp. strain PCC 7002

    Andrew L. Markley;Matthew B. Begemann;Ryan E. Clarke;Gina C. Gordon

  • Modular synthase-encoding gene involved in α-olefin biosynthesis in Synechococcus sp. strain PCC 7002.

    Daniel Mendez-Perez;Matthew B. Begemann;Brian F. Pfleger;Brian F. Pfleger

  • CRISPR interference as a titratable, trans-acting regulatory tool for metabolic engineering in the cyanobacterium Synechococcus sp. strain PCC 7002

    Gina C. Gordon;Travis C. Korosh;Jeffrey C. Cameron;Andrew L. Markley

  • Metabolic engineering strategies for microbial synthesis of oleochemicals.

    Brian F. Pfleger;Michael Gossing;Jens Nielsen

  • Membrane Stresses Induced by Overproduction of Free Fatty Acids in Escherichia coli

    Rebecca M. Lennen;Rebecca M. Lennen;Max A. Kruziki;Kritika Kumar;Robert A. Zinkel;Robert A. Zinkel

  • Directed evolution of AraC for improved compatibility of arabinose- and lactose-inducible promoters.

    Sung Kuk Lee;Howard H. Chou;Brian F. Pfleger;Jack D. Newman

  • Genetic tools for reliable gene expression and recombineering in Pseudomonas putida

    Taylor B. Cook;Jacqueline M. Rand;Wasti Nurani;Dylan K. Courtney

  • Biosynthetic Analysis of the Petrobactin Siderophore Pathway from Bacillus anthracis

    Jung Yeop Lee;Brian K. Janes;Karla D. Passalacqua;Brian F. Pfleger

  • Identification of Transport Proteins Involved in Free Fatty Acid Efflux in Escherichia coli

    Rebecca M. Lennen;Mark G. Politz;Max A. Kruziki;Brian F. Pfleger;Brian F. Pfleger

  • Production of medium chain length fatty alcohols from glucose in Escherichia coli.

    J. Tyler Youngquist;Martin H. Schumacher;Joshua P. Rose;Thomas C. Raines

  • Microbial sensors for small molecules: development of a mevalonate biosensor.

    Brian F. Pfleger;Douglas J. Pitera;Jack D. Newman;Vincent J.J. Martin

  • Transcription control engineering and applications in synthetic biology.

    Michael D. Engstrom;Brian F. Pfleger

Frequent Co-Authors

Jay D. Keasling
Jay D. Keasling University of California, Berkeley
James A. Dumesic
James A. Dumesic University of Wisconsin–Madison
Costas D. Maranas
Costas D. Maranas Pennsylvania State University
Jennifer L. Reed
Jennifer L. Reed University of Wisconsin–Madison
Katherine D. McMahon
Katherine D. McMahon University of Wisconsin–Madison
David H. Sherman
David H. Sherman University of Michigan–Ann Arbor
Philip C. Hanna
Philip C. Hanna University of Michigan–Ann Arbor
Mary S. Lipton
Mary S. Lipton Pacific Northwest National Laboratory
Andrzej Joachimiak
Andrzej Joachimiak Argonne National Laboratory
Adam P. Arkin
Adam P. Arkin Lawrence Berkeley National Laboratory

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