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Neuroscience

D-Index
59
Citations
16957
World Ranking
3944
National Ranking
1790

Overview

Jack M. Parent is affiliated with the University of Michigan-Ann Arbor in the United States. Their research encompasses multiple areas within biochemistry, genetics, molecular biology, neuroscience, and medicine, with a strong focus on molecular biology and cellular and molecular neuroscience.

The scientist has contributed extensively to research in fields such as:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience
  • Medicine

Within these fields, the research covers several subfields, including:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Genetics
  • Psychiatry and Mental Health
  • Cognitive Neuroscience

The main topics addressed in their work are:

  • Neuroscience and Neuropharmacology Research
  • Epilepsy Research and Treatment
  • Genetics and Neurodevelopmental Disorders
  • Pluripotent Stem Cells Research
  • CRISPR and Genetic Engineering
  • Neuroscience and Neural Engineering
  • Pharmacological Effects and Toxicity Studies

Jack M. Parent has published in a range of scientific venues, with a considerable number of publications appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of Neurology
  • Nature Neuroscience
  • Frontiers in Cellular Neuroscience
  • Epilepsia Open

Frequent coauthors in their publications include:

  • Andrew M. Tidball
  • Lori L. Isom
  • J. Clayton Walker
  • Wei Niu
  • Sandra P. Mojica-Perez

Significant recent papers authored or coauthored by Jack M. Parent feature a focus on neural mechanisms, epilepsy, and genetic disorders, such as:

  • Identification of neural oscillations and epileptiform changes in human brain organoids (2021, Nature Neuroscience)
  • Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome (2020, Annals of Neurology)
  • Variant-specific changes in persistent or resurgent sodium current in SCN8A-related epilepsy patient-derived neurons (2020, Brain)
  • A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis (2020, Nature Neuroscience)
  • Surge of neurophysiological coupling and connectivity of gamma oscillations in the dying human brain (2023, Proceedings of the National Academy of Sciences)

Best Publications

  • Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus

    Jack M. Parent;Timothy W. Yu;Rebecca T. Leibowitz;Daniel H. Geschwind

  • De novo mutations in epileptic encephalopathies

    Andrew S. Allen;Samuel F. Berkovic;Patrick Cossette;Norman Delanty

  • Rat forebrain neurogenesis and striatal neuron replacement after focal stroke.

    Jack M. Parent;Zinaida S. Vexler;Chao Gong;Nikita Derugin

  • Forebrain neurogenesis after focal Ischemic and traumatic brain injury.

    Steven G. Kernie;Jack M. Parent

  • Injury-Induced Neurogenesis in the Adult Mammalian Brain

    Jack M. Parent

  • Aberrant seizure-induced neurogenesis in experimental temporal lobe epilepsy.

    Jack M. Parent;Robert C. Elliott;Samuel J. Pleasure;Nicholas M. Barbaro

  • Prolonged Seizures Increase Proliferating Neuroblasts in the Adult Rat Subventricular Zone–Olfactory Bulb Pathway

    Jack M. Parent;Vivian V. Valentin;Daniel H. Lowenstein

  • Adult neurogenesis and the ischemic forebrain.

    Robin J Lichtenwalner;Jack M Parent

  • X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats

    E Tada;J.M Parent;D.H Lowenstein;J.R Fike

  • Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke

    Seong Ryong Lee;Hahn Young Kim;Jadwiga Rogowska;Bing Qiao Zhao

  • Inhibition of Dentate Granule Cell Neurogenesis with Brain Irradiation Does Not Prevent Seizure-Induced Mossy Fiber Synaptic Reorganization in the Rat

    Jack M. Parent;Eiji Tada;John R. Fike;Daniel H. Lowenstein

  • Increased dentate granule cell neurogenesis following amygdala kindling in the adult rat.

    Jack M Parent;Sridevi Janumpalli;James O McNamara;James O McNamara;Daniel H Lowenstein

  • Reelin Regulates Neuronal Progenitor Migration in Intact and Epileptic Hippocampus

    Chao Gong;Tsu Wei Wang;Holly S. Huang;Jack M. Parent

  • Identification of neural oscillations and epileptiform changes in human brain organoids.

    Ranmal A Samarasinghe;Osvaldo A Miranda;Jessie E Buth;Simon Mitchell;Simon Mitchell

  • Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism

    Yu Liu;Luis F. Lopez-Santiago;Yukun Yuan;Julie M. Jones

  • The developmental stage of dentate granule cells dictates their contribution to seizure-induced plasticity.

    Michelle M. Kron;Helen Zhang;Jack M. Parent

  • A roadmap for precision medicine in the epilepsies

    S. F. Berkovic;I. E. Scheffer;S. Petrou;N. Delanty

  • Seizure-induced neurogenesis: are more new neurons good for an adult brain?

    Jack M. Parent;Daniel H. Lowenstein

  • Derivation of mesenchymal stem cells from human induced pluripotent stem cells cultured on synthetic substrates.

    L.G. Villa-Diaz;S.E. Brown;Y. Liu;A.M. Ross

  • Adult neurogenesis in the intact and epileptic dentate gyrus.

    Jack M. Parent

  • Ultra-rare genetic variation in common epilepsies: a case-control sequencing study.

    Andrew S Allen;Susannah T Bellows;Samuel F Berkovic;Joshua Bridgers

  • Erratum: De Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies (American Journal of Human Genetics (2014) 95(4) (360–370)(S0002929714003838)(10.1016/j.ajhg.2014.08.013))

    Silke Appenzeller;Rudi Balling;Nina Barisic;Stéphanie Baulac

Frequent Co-Authors

Daniel H. Lowenstein
Daniel H. Lowenstein University of California, San Francisco
Geoffrey G. Murphy
Geoffrey G. Murphy University of Michigan–Ann Arbor
Ingrid E. Scheffer
Ingrid E. Scheffer University of Melbourne
Dennis J. Dlugos
Dennis J. Dlugos Children's Hospital of Philadelphia
Samuel F. Berkovic
Samuel F. Berkovic University of Melbourne
Robert C. Knowlton
Robert C. Knowlton University of California, San Francisco
Heather C. Mefford
Heather C. Mefford University of Washington
Erin L. Heinzen
Erin L. Heinzen University of North Carolina at Chapel Hill
Miriam H. Meisler
Miriam H. Meisler University of Michigan–Ann Arbor
Joseph I Sirven
Joseph I Sirven Mayo Clinic

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