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Immunology

D-Index
70
Citations
18996
World Ranking
2400
National Ranking
1152

Overview

Thomas J. Braciale is affiliated with the University of Virginia in the United States. Their research contributions span multiple areas within medicine and molecular biology, with a significant focus on immunology and infectious diseases.

The scientist's recent publications include:

  • Montelukast in hospitalized patients diagnosed with COVID-19, 2021, Journal of Asthma
  • Bronchoalveolar lavage cytokine patterns in children with severe neutrophilic and paucigranulocytic asthma, 2020, Journal of Allergy and Clinical Immunology
  • Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in COVID-19, 2023, Science Immunology
  • Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of alveolar macrophages, 2023, iScience
  • Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling, 2020, Science Signaling

Their frequent co-authors include:

  • Bibo Zhu
  • Yue Wu
  • Tochukwu Ozulumba
  • Jonathan M. Zatorski
  • Abhinav Arneja

Their research has appeared repeatedly in several journals, especially:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Journal of Allergy and Clinical Immunology
  • Journal of Asthma
  • Science Immunology

Braciale's main fields of study are Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Subfields include Immunology, Molecular Biology, Infectious Diseases, Pulmonary and Respiratory Medicine, and Neurology.

The scientist has engaged comprehensively with a variety of research topics, notably:

  • Immune cells in cancer
  • Single-cell and spatial transcriptomics
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • 3D Printing in Biomedical Research
  • Pharmacological Receptor Mechanisms and Effects
  • Asthma and respiratory diseases

Best Publications

  • Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10

    Jie Sun;Rajat Madan;Christopher L Karp;Thomas J Braciale

  • The host immune response in respiratory virus infection: balancing virus clearance and immunopathology

    Amy H. Newton;Amber Cardani;Thomas J. Braciale

  • Accelerated Migration of Respiratory Dendritic Cells to the Regional Lymph Nodes Is Limited to the Early Phase of Pulmonary Infection

    Kevin L Legge;Thomas J Braciale

  • Local-pooled-error test for identifying differentially expressed genes with a small number of replicated microarrays

    Nitin Jain;Jayant Thatte;Thomas Braciale;Klaus Ley

  • Regulating the adaptive immune response to respiratory virus infection

    Thomas J. Braciale;Jie Sun;Jie Sun;Taeg S. Kim

  • In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific.

    Unknown

  • Virus-specific CD8+ T Lymphocytes Downregulate T Helper Cell Type 2 Cytokine Secretion and Pulmonary Eosinophilia during Experimental Murine Respiratory Syncytial Virus Infection

    Anon Srikiatkhachorn;Thomas J. Braciale

  • Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation

    David J. Kittlesen;Kimberly A. Chianese-Bullock;Zhi Qiang Yao;Thomas J. Braciale

  • Influenza virus-specific CD4+ T helper type 2 T lymphocytes do not promote recovery from experimental virus infection.

    M B Graham;V L Braciale;T J Braciale

  • Respiratory dendritic cell subsets differ in their capacity to support the induction of virus-specific cytotoxic CD8+ T cell responses.

    Taeg S. Kim;Thomas J. Braciale

  • Resistance to and Recovery from Lethal Influenza Virus Infection in B Lymphocyte–deficient Mice

    Mary Beth Graham;Thomas J. Braciale

  • Response to influenza infection in mice with a targeted disruption in the interferon gamma gene.

    M B Graham;D K Dalton;D Giltinan;V L Braciale

  • Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation.

    Chang S. Hahn;Young S. Hahn;Thomas J. Braciale;Charles M. Rice

  • Activation, Differentiation, and Migration of Naive Virus-Specific CD8+ T Cells during Pulmonary Influenza Virus Infection

    Christopher W. Lawrence;Thomas J. Braciale;Thomas J. Braciale

  • Respiratory syncytial virus infection suppresses lung CD8+ T-cell effector activity and peripheral CD8+ T-cell memory in the respiratory tract.

    Jun Chang;Thomas J. Braciale

  • Preferential migration of effector CD8+ T cells into the interstitium of the normal lung

    Elena Galkina;Jayant Thatte;Vrushali Dabak;Mark B. Williams

  • CD4 + T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs

    Jie Sun;Haley Dodd;Emily K Moser;Rahul Sharma

  • Frequency, Specificity, and Sites of Expansion of CD8+ T Cells during Primary Pulmonary Influenza Virus Infection

    Christopher W. Lawrence;Rebecca M. Ream;Thomas J. Braciale;Thomas J. Braciale

  • Lymph Node Dendritic Cells Control CD8+ T Cell Responses through Regulated FasL Expression

    Kevin L. Legge;Thomas J. Braciale

  • Antigen persistence and the control of local T cell memory by migrant respiratory dendritic cells after acute virus infection.

    Taeg S. Kim;Matthew M. Hufford;Jie Sun;Yang Xin Fu

  • Immunopathology in RSV Infection Is Mediated by a Discrete Oligoclonal Subset of Antigen-Specific CD4+ T Cells

    Steven Michael Varga;Xiaoting Z. Wang;Raymond M. Welsh;Thomas J. Braciale

Frequent Co-Authors

Larry Borish
Larry Borish University of Virginia
Young S. Hahn
Young S. Hahn University of Virginia
Steven M. Varga
Steven M. Varga University of Iowa
Mark H. Stoler
Mark H. Stoler University of Virginia
Klaus Ley
Klaus Ley Augusta University
Jonathan Kipnis
Jonathan Kipnis Washington University in St. Louis
Barney S. Graham
Barney S. Graham Morehouse School of Medicine
jeffrey a whitsett
jeffrey a whitsett Cincinnati Children's Hospital Medical Center
Ann R. Falsey
Ann R. Falsey University of Rochester
Adolfo García-Sastre
Adolfo García-Sastre Icahn School of Medicine at Mount Sinai

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