2026 David J. Topham: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	69	2505	2302	1204	1098	240	17620

Overview

David J. Topham is affiliated with the University of Rochester Medical Center in the United States. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with significant attention to Immunology, Epidemiology, Molecular Biology, Infectious Diseases, and Pulmonary and Respiratory Medicine as subfields.

Topham's work addresses a range of topics within biomedical and immunological research. These topics include:

Respiratory viral infections research
Immune Cell Function and Interaction
T-cell and B-cell Immunology
Influenza Virus Research Studies
SARS-CoV-2 and COVID-19 Research
Immune Response and Inflammation
Tracheal and airway disorders

Among their recent papers are:

Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19, 2021, published in mBio
S Protein-Reactive IgG and Memory B Cell Production after Human SARS-CoV-2 Infection Includes Broad Reactivity to the S2 Subunit, 2020, published in mBio
Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19, 2020, published in Nature Reviews Immunology
T _RM integrins CD103 and CD49a differentially support adherence and motility after resolution of influenza virus infection, 2020, published in Proceedings of the National Academy of Sciences
Association of Human Milk Antibody Induction, Persistence, and Neutralizing Capacity With SARS-CoV-2 Infection vs mRNA Vaccination, 2021, published in JAMA Pediatrics

Topham's frequent co-authors include Mark Y. Sangster, Thomas J. Mariani, Mary T. Caserta, Emma C. Reilly, and Phuong Nguyen-Contant. This collaboration suggests a research network focused on immunology and viral infection studies.

The primary venues where their work has been published with high frequency are bioRxiv (Cold Spring Harbor Laboratory), PLoS Pathogens, The Journal of Infectious Diseases, The Journal of Immunology, and mBio.

Best Publications

Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors

Evan Parganas;Demin Wang;Dimitrios Stravopodis;David J. Topham

1367
Citations
Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells

Richard Moriggl;David J Topham;Stephan Teglund;Veronika Sexl

712
Citations
CD8+ T cells clear influenza virus by perforin or Fas-dependent processes.

D J Topham;R A Tripp;P C Doherty

638
Citations
SOCS1 Deficiency Causes a Lymphocyte-Dependent Perinatal Lethality

Jean Christophe Marine;David J. Topham;Catriona McKay;Demin Wang

632
Citations
Effector CD4+ and CD8+ T-cell mechanisms in the control of respiratory virus infections.

Peter C. Doherty;David J. Topham;Ralph A. Tripp;Rhonda D. Cardin

533
Citations
SOCS3 Is Essential in the Regulation of Fetal Liver Erythropoiesis

Jean Christophe Marine;Catriona McKay;Demin Wang;David J. Topham

476
Citations
Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies

Yao Qing Chen;Teddy John Wohlbold;Nai Ying Zheng;Min Huang

422
Citations
Kupffer cell heterogeneity: functional properties of bone marrow derived and sessile hepatic macrophages.

Ingo Klein;Judith C. Cornejo;Noelle K. Polakos;Beena John

417
Citations
Neutrophil trails guide influenza-specific CD8+ T cells in the airways

Kihong Lim;Young Min Hyun;Kris Lambert-Emo;Tara Capece

405
Citations
The Collagen Binding α1β1 Integrin VLA-1 Regulates CD8 T Cell-Mediated Immune Protection against Heterologous Influenza Infection

Steven J Ray;Suzanne N Franki;Robert H Pierce;Snezhana Dimitrova

383
Citations
Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection.

Carole J. Henry Dunand;Paul E. Leon;Min Huang;Angela Choi

289
Citations
Quantifying the Early Immune Response and Adaptive Immune Response Kinetics in Mice Infected with Influenza A Virus

Hongyu Miao;Joseph A. Hollenbaugh;Martin S. Zand;Jeanne Holden-Wiltse

253
Citations
Stat5 Activation Is Uniquely Associated with Cytokine Signaling in Peripheral T Cells

Richard Moriggl;Veronika Sexl;Roland Piekorz;David Topham

247
Citations
S Protein-Reactive IgG and Memory B Cell Production after Human SARS-CoV-2 Infection Includes Broad Reactivity to the S2 Subunit

Phuong Nguyen-Contant;A. Karim Embong;Preshetha Kanagaiah;Francisco A. Chaves

246
Citations
Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19.

Ryan M. Pace;Janet E. Williams;Kirsi M. Järvinen;Mandy B. Belfort

241
Citations
Simulation and Prediction of the Adaptive Immune Response to Influenza A Virus Infection

Ha Youn Lee;David J. Topham;Sung Yong Park;Joseph Hollenbaugh

233
Citations
Clearance of an Influenza A Virus by CD4+ T Cells Is Inefficient in the Absence of B Cells

David J. Topham;Peter C. Doherty

233
Citations
Transduction of murine bone marrow cells with an MDR1 vector enables ex vivo stem cell expansion, but these expanded grafts cause a myeloproliferative syndrome in transplanted mice.

Kevin D. Bunting;Jacques Galipeau;David Topham;Ely Benaim

230
Citations
Tissue-Resident Memory CD8+ T Cells: From Phenotype to Function.

David J. Topham;Emma C. Reilly

218
Citations
Platelets Present Antigen in the Context of MHC Class I

Lesley M. Chapman;Angela A. Aggrey;David J. Field;Kalyan Srivastava

204
Citations
Thymic lymphoproliferative disease after successful correction of CD40 ligand deficiency by gene transfer in mice

Michael P. Brown;David J. Topham;Mark Y. Sangster;Jingfeng Zhao

203
Citations
Establishment and Persistence of Virus‐Specific CD4+ and CD8+ T Cell Memory

Peter C. Doherty;David J. Topham;Ralph A. Tripp

200
Citations

Frequent Co-Authors

Ann R. Falsey University of Rochester

John J. Treanor University of Rochester Medical Center

Luis Martínez-Sobrido Texas Biomedical Research Institute

Edward E. Walsh University of Rochester Medical Center

Peter C. Doherty University of Melbourne

Steven R. Gill University of Rochester Medical Center

Tim R. Mosmann University of Rochester Medical Center

Hulin Wu The University of Texas Health Science Center at Houston

Florian Krammer Icahn School of Medicine at Mount Sinai

Andrea J. Sant University of Rochester Medical Center

External Links

Personal website of David J. Topham

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