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Biology and Biochemistry

D-Index
56
Citations
14213
World Ranking
14254
National Ranking
6011

Overview

Liang-Jun Yan is affiliated with the University of North Texas Health Science Center in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several related subfields including Physiology, Molecular Biology, Pulmonary and Respiratory Medicine, Neurology, and Nephrology.

Their work has contributed to topics such as diet and metabolism studies, adipose tissue and metabolism, biochemical acid research studies, metabolism and genetic disorders, mitochondrial function and pathology, neuroinflammation and neurodegeneration mechanisms, and dietary effects on health.

Liang-Jun Yan has published extensively in several academic journals and scientific venues. Frequent publication venues include:

  • Biomolecules
  • Nutrients
  • Frontiers in Cell and Developmental Biology
  • Free Radicals and Antioxidants
  • Frontiers in Endocrinology

Among their recent research papers are:

  • Cadmium-Induced Kidney Injury: Oxidative Damage as a Unifying Mechanism (2021, Biomolecules)
  • Folic acid-induced animal model of kidney disease (2021, Animal Models and Experimental Medicine)
  • Reductive Stress-Induced Mitochondrial Dysfunction and Cardiomyopathy (2020, Oxidative Medicine and Cellular Longevity)
  • NADH/NAD+ Redox Imbalance and Diabetic Kidney Disease (2021, Biomolecules)
  • The Nicotinamide/Streptozotocin Rodent Model of Type 2 Diabetes: Renal Pathophysiology and Redox Imbalance Features (2022, Biomolecules)

Collaborations form a notable part of Liang-Jun Yan's academic activity. Frequent co-authors include:

  • Tram N. Diep
  • Haoxin Liu
  • WEI-XING MA
  • Yucheng Wang

The scientist's research integrates molecular biology and medicine to explore mechanisms of kidney disease, metabolic disorders, redox biology, and mitochondrial function. Their work often involves animal models and biochemical investigations linking oxidative and reductive stress to organ pathology.

Best Publications

  • Oxidative DNA damage and senescence of human diploid fibroblast cells.

    Qin Chen;Ann Fischer;Joshua D. Reagan;Liang Jun Yan

  • Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases.

    Ankita Nandi;Liang Jun Yan;Chandan Kumar Jana;Nilanjana Das

  • Oxidative damage during aging targets mitochondrial aconitase

    Liang-Jun Yan;Rodney L. Levine;Rajindar S. Sohal

  • Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice

    Marzia Scortegagna;Kan Ding;Yavuz Oktay;Arti Gaur

  • Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer's disease

    Zhiyou Cai;M. Delwar Hussain;Liang Jun Yan

  • Mitochondrial adenine nucleotide translocase is modified oxidatively during aging

    Liang Jun Yan;Rajindar S. Sohal

  • Human αB-Crystallin Mutation Causes Oxido-Reductive Stress and Protein Aggregation Cardiomyopathy in Mice

    Namakkal S. Rajasekaran;Patrice Connell;Elisabeth S. Christians;Liang Jun Yan

  • Pathogenesis of Chronic Hyperglycemia: From Reductive Stress to Oxidative Stress

    Liang Jun Yan

  • UV-irradiation depletes antioxidants and causes oxidative damage in a model of human skin.

    Maurizio Podda;Maret G Traber;Christine Weber;Liang-Jun Yan

  • Heat shock factor 1 and heat shock proteins: critical partners in protection against acute cell injury.

    Elisabeth S. Christians;Liang Jun Yan;Ivor J. Benjamin

  • Protein Oxidative Modifications: Beneficial Roles in Disease and Health.

    Zhiyou Cai;Liang-Jun Yan

  • Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage

    Liang Jun Yan;Elisabeth S. Christians;Li Liu;XianZhong Xiao

  • Alternative Mitochondrial Electron Transfer as a Novel Strategy for Neuroprotection

    Yi Wen;Wenjun Li;Ethan C. Poteet;Luokun Xie

  • Streptozotocin-induced type 1 diabetes in rodents as a model for studying mitochondrial mechanisms of diabetic β cell glucotoxicity.

    Jinzi Wu;Liang-Jun Yan

  • Redox imbalance stress in diabetes mellitus: Role of the polyol pathway.

    Liang-jun Yan

  • Role of RAGE in Alzheimer’s Disease

    Zhiyou Cai;Nannuan Liu;Chuanling Wang;Biyong Qin

  • Pyruvate protects mitochondria from oxidative stress in human neuroblastoma SK-N-SH cells.

    Xiaofei Wang;Evelyn Perez;Ran Liu;Liang-Jun Yan

  • Positive oxidative stress in aging and aging-related disease tolerance

    Liang-Jun Yan

  • Roles of AMP-activated Protein Kinase in Alzheimer’s Disease

    Zhiyou Cai;Liang-Jun Yan;Keshen Li;Sohel H. Quazi

  • Sources and implications of NADH/NAD(+) redox imbalance in diabetes and its complications.

    Jinzi Wu;Zhen Jin;Hong Zheng;Liang Jun Yan

Frequent Co-Authors

Lester Packer
Lester Packer University of Southern California
Ivor J. Benjamin
Ivor J. Benjamin Medical College of Wisconsin
Rajindar S. Sohal
Rajindar S. Sohal University of Southern California
James W. Simpkins
James W. Simpkins West Virginia University
Maret G. Traber
Maret G. Traber Oregon State University
Rodney L. Levine
Rodney L. Levine National Institutes of Health
Michael J. Bennett
Michael J. Bennett University Hospital Southampton NHS Foundation Trust
Rajindar S. Sohal
Rajindar S. Sohal University of Southern California
Bruce N. Ames
Bruce N. Ames University of California, Berkeley
Jiankang Liu
Jiankang Liu Xi'an Jiaotong University

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