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Sidonia Fagarasan

Sidonia Fagarasan

D-Index & Metrics

Immunology

D-Index
56
Citations
23872
World Ranking
3663
National Ranking
145

Overview

Sidonia Fagarasan is affiliated with RIKEN in Japan and has contributed to various fields primarily within biochemistry, genetics, molecular biology, immunology, and microbiology, with additional work intersecting medicine. Their research encompasses subfields including molecular biology, immunology, emergency medical services, biological psychiatry, and microbiology.

The scientist's main research topics include immune cell function and interaction, gut microbiota and health, pediatric health and respiratory diseases, T-cell and B-cell immunology, tryptophan and brain disorders, polyamine metabolism and applications, and antimicrobial peptides and activities.

Frequent publication venues for their research are:

  • Trends in Immunology
  • Nature
  • Science
  • Trends in Cell Biology
  • Arthritis & Rheumatology

Sidonia Fagarasan's recent papers illustrate a focus on immune mechanisms and antitumor responses, including:

  • "B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity," 2021, Nature
  • "Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice," 2022, Science
  • "Spermidine - an old molecule with a new age-defying immune function," 2023, Trends in Cell Biology
  • "Effect of Impaired T Cell Receptor Signaling on the Gut Microbiota in a Mouse Model of Systemic Autoimmunity," 2021, Arthritis & Rheumatology
  • "Circulation of gut-preactivated naïve CD8+T cells enhances antitumor immunity in B cell-defective mice," 2020, Proceedings of the National Academy of Sciences

The scientist has collaborated frequently with a core group of co-authors, including Baihao Zhang, Tasuku Honjo, Kenji Chamoto, Yuki Sugiura, and Rosemary J. Menzies. These collaborations have resulted in multiple joint publications demonstrating sustained research partnerships.

Best Publications

  • Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

    Masamichi Muramatsu;Kazuo Kinoshita;Sidonia Fagarasan;Shuichi Yamada

  • Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

    Laurence Macia;Jian Tan;Angelica T. Vieira;Katie Leach

  • Foxp3+ follicular regulatory T cells control the germinal center response

    Michelle A. Linterman;Wim Pierson;Sau K. Lee;Axel Kallies

  • A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application.

    Taku Okazaki;Shunsuke Chikuma;Yoshiko Iwai;Sidonia Fagarasan

  • Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut

    Keiichiro Suzuki;Bob Meek;Yasuko Doi;Masamichi Muramatsu

  • Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora.

    Sidonia Fagarasan;Masamichi Muramatsu;Keiichiro Suzuki;Hitoshi Nagaoka

  • Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches

    Masayuki Tsuji;Noriko Komatsu;Shimpei Kawamoto;Keiichiro Suzuki

  • Intestinal IgA synthesis: regulation of front-line body defences.

    Sidonia Fagarasan;Tasuku Honjo

  • Foxp3+ T Cells Regulate Immunoglobulin A Selection and Facilitate Diversification of Bacterial Species Responsible for Immune Homeostasis

    Shimpei Kawamoto;Mikako Maruya;Lucia M. Kato;Wataru Suda

  • In situ class switching and differentiation to IgA-producing cells in the gut lamina propria

    Sidonia Fagarasan;Kazuo Kinoshita;Masamichi Muramatsu;Koichi Ikuta

  • T-Independent immune response: new aspects of B cell biology.

    Sidonia Fagarasan;Tasuku Honjo

  • Adaptive Immune Regulation in the Gut: T Cell–Dependent and T Cell–Independent IgA Synthesis

    Sidonia Fagarasan;Shimpei Kawamoto;Osami Kanagawa;Keiichiro Suzuki

  • The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells

    Ajithkumar Vasanthakumar;Kazuyo Moro;Annie Xin;Yang Liao

  • The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut.

    Shimpei Kawamoto;Thinh H. Tran;Mikako Maruya;Keiichiro Suzuki

  • Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.

    Masayuki Tsuji;Keiichiro Suzuki;Hiroshi Kitamura;Mikako Maruya

  • Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity

    Kenji Chamoto;Partha S. Chowdhury;Alok Kumar;Kazuhiro Sonomura;Kazuhiro Sonomura

  • B cell-derived GABA elicits IL-10 + macrophages to limit anti-tumour immunity

    Baihao Zhang;Alexis Vogelzang;Michio Miyajima;Yuki Sugiura

  • Regulation of B1 cell migration by signals through Toll-like receptors.

    Seon-ah Ha;Masayuki Tsuji;Keiichiro Suzuki;Bob Meek

  • PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

    Taku Okazaki;Il-mi Okazaki;Jian Wang;Daisuke Sugiura

  • B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells

    Sau K. Lee;Robert J. Rigby;Dimitra Zotos;Louis M. Tsai

  • Foxp3(+) follicular regulatory T cells control the germinal centre response

    M. A Linterman;Wim Pierson;S. K Lee;A Kallies

Frequent Co-Authors

Tasuku Honjo
Tasuku Honjo Kyoto University
Masamichi Muramatsu
Masamichi Muramatsu National Institutes of Health
Michelle A. Linterman
Michelle A. Linterman Babraham Institute
Carola G. Vinuesa
Carola G. Vinuesa Australian National University
Axel Kallies
Axel Kallies University of Melbourne
Osami Kanagawa
Osami Kanagawa École Normale Supérieure de Lyon
Koichi Ikuta
Koichi Ikuta Kyoto University
Andrea Cerutti
Andrea Cerutti Icahn School of Medicine at Mount Sinai
Adrian Liston
Adrian Liston University of Cambridge
Fumihiko Matsuda
Fumihiko Matsuda Kyoto University

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