Sidonia Fagarasan mainly focuses on Immunology, Immune system, Germinal center, Immunoglobulin class switching and Immunity. Her research investigates the connection with Immunology and areas like Cell biology which intersect with concerns in T cell. Her work deals with themes such as Cell and Microbiology, which intersect with Immune system.
Her work carried out in the field of Germinal center brings together such families of science as CD40, Somatic hypermutation, Activation-induced deaminase, Cytidine deaminase and FOXP3. Her Immunoglobulin class switching research incorporates themes from Molecular biology and Stromal cell. The various areas that Sidonia Fagarasan examines in her Immunity study include Marginal zone, Immune tolerance and B-1 cell.
Sidonia Fagarasan spends much of her time researching Immunology, Immune system, Germinal center, Gut flora and Antibody. Her studies link Cell biology with Immunology. Her study explores the link between Immune system and topics such as Microbiology that cross with problems in Gastrointestinal tract.
Her biological study spans a wide range of topics, including Follicular phase, CD40, Somatic hypermutation, Follicular dendritic cells and FOXP3. Her research integrates issues of Acquired immune system and Homeostasis in her study of Gut flora. Her research in Molecular biology tackles topics such as Immunoglobulin class switching which are related to areas like Stromal cell and Cytidine deaminase.
Her primary areas of investigation include Immune system, Immunology, Antibody, Gut flora and Amino acid. Many of her studies on Immune system involve topics that are commonly interrelated, such as Effector. Her study in Immunology is interdisciplinary in nature, drawing from both Genetic predisposition and Chromosomal translocation.
Her work on Germinal center as part of general Antibody study is frequently linked to Symbiotic bacteria, bridging the gap between disciplines. In her study, Secretory IgA and Microbiology is strongly linked to Mutualism, which falls under the umbrella field of Germinal center. Her Gut flora study combines topics from a wide range of disciplines, such as Microbiome, Regulation of gene expression, Ovalbumin and Autoimmune disease.
Her main research concerns Immunology, Immune system, Gut flora, T cell and Antibody. Her Immunology and Autoimmunity, CTLA-4, Regulatory T cell, FOXP3 and Immune tolerance investigations all form part of her Immunology research activities. Sidonia Fagarasan has included themes like Receptor, Internal medicine, Dopamine and Effector in her Immune system study.
The concepts of her Gut flora study are interwoven with issues in Ovalbumin, Microbiology, Function and Bacteria. Her T cell research includes themes of Cancer research, Protein kinase A, Blockade, Mechanistic target of rapamycin and Serotonin. Her study in the field of Secretory IgA and Germinal center also crosses realms of Antibody Isotype.
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Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
Masamichi Muramatsu;Kazuo Kinoshita;Sidonia Fagarasan;Shuichi Yamada.
Foxp3+ follicular regulatory T cells control the germinal center response
Michelle A. Linterman;Michelle A. Linterman;Wim Pierson;Sau K. Lee;Axel Kallies.
Nature Medicine (2011)
Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
Keiichiro Suzuki;Bob Meek;Yasuko Doi;Masamichi Muramatsu.
Proceedings of the National Academy of Sciences of the United States of America (2004)
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application.
Taku Okazaki;Shunsuke Chikuma;Yoshiko Iwai;Sidonia Fagarasan.
Nature Immunology (2013)
Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora.
Sidonia Fagarasan;Masamichi Muramatsu;Keiichiro Suzuki;Hitoshi Nagaoka.
Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.
Masayuki Tsuji;Noriko Komatsu;Shimpei Kawamoto;Keiichiro Suzuki.
Intestinal IgA synthesis: regulation of front-line body defences.
Sidonia Fagarasan;Tasuku Honjo.
Nature Reviews Immunology (2003)
Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome
Laurence Macia;Jian Tan;Angelica T. Vieira;Katie Leach.
Nature Communications (2015)
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
Sidonia Fagarasan;Kazuo Kinoshita;Masamichi Muramatsu;Koichi Ikuta.
T-Independent Immune Response: New Aspects of B Cell Biology
Sidonia Fagarasan;Tasuku Honjo.
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