Senji Shirasawa

Overview

Best Publications

• Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.

  J. Rak;Y. Mitsuhashi;L. Bayko;J. Filmus

  1048
  Citations

• Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

  Senji Shirasawa;Masanori Furuse;Nobuhiko Yokoyama;Takehiko Sasazuki

  954
  Citations

• Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis.

  Joanne L. Yu;Linda May;Vladimir Lhotak;Siranoush Shahrzad

  769
  Citations

• A functional variant in FCRL3 , encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

  Yuta Kochi;Ryo Yamada;Akari Suzuki;John B. Harley;John B. Harley;John B. Harley

  487
  Citations

• Opposing Effects of Ras on p53: Transcriptional Activation of mdm2 and Induction of p19ARF

  Stefan Ries;Carola Biederer;Douglas Woods;Ohad Shifman

  468
  Citations

• 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors.

  Qing Bai She;Ensar Halilovic;Qing Ye;Wei Zhen

  464
  Citations

• Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus

  Federica Di Nicolantonio;Sabrina Arena;Josep Tabernero;Stefano Grosso

  402
  Citations

• Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates

  Leping Cheng;Akiko Arata;Rumiko Mizuguchi;Ying Qian

  393
  Citations

• Impact of oncogenes in tumor angiogenesis: Mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

  Futoshi Okada;Janusz W. Rak;Brad St. Croix;Blandine Lieubeau

  378
  Citations

• Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes

  Leping Cheng;Omar Abdel Samad;Yi Xu;Rumiko Mizuguchi

  272
  Citations

• Identification of susceptibility loci for autoimmune thyroid disease to 5q31–q33 and Hashimoto’s thyroiditis to 8q23–q24 by multipoint affected sib-pair linkage analysis in Japanese

  Kenji Sakai;Senji Shirasawa;Naofumi Ishikawa;Kunihiko Ito

  263
  Citations

• Sensitization to the Lysosomal Cell Death Pathway by Oncogene-Induced Down-regulation of Lysosome-Associated Membrane Proteins 1 and 2

  Nicole Fehrenbacher;Lone Bastholm;Thomas Kirkegaard-Sørensen;Bo Rafn

  260
  Citations

• Competition between human cells by entosis.

  Qiang Sun;Tianzhi Luo;Yixin Ren;Oliver Florey

  226
  Citations

• Inhibition of interferon gamma signaling by the short chain fatty acid butyrate.

  Lidija Klampfer;Jie Huang;Takehiko Sasazuki;Senji Shirasawa

  220
  Citations

• Enx (Hox11L1)-deficient mice develop myenteric neuronal hyperplasia and megacolon

  Senji Shirasawa;Anne Marie R. Yunker;Kevin A. Roth;Gary A. Brown

  180
  Citations

• BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study

  Eleni Makrodouli;Eftychia Oikonomou;Michal Koc;Ladislav Andera

  174
  Citations

• Oncogenic K-RAS is required to maintain changes in cytoskeletal organization, adhesion, and motility in colon cancer cells.

  Claire B. Pollock;Senji Shirasawa;Takehiko Sasazuki;Walter Kolch

  174
  Citations

• Formation of brainstem (nor)adrenergic centers and first-order relay visceral sensory neurons is dependent on homeodomain protein Rnx/Tlx3.

  Ying Qian;Bernd Fritzsch;Senji Shirasawa;Chih-Li Chen

  172
  Citations

• Rnx deficiency results in congenital central hypoventilation

  Senji Shirasawa;Akiko Arata;Hiroshi Onimaru;Kevin A. Roth

  169
  Citations

• Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells.

  Iwai Baba;Senji Shirasawa;Ryo Iwamoto;Koji Okumura

  163
  Citations