World's Best Scientists 2026 revealed!
Senji Shirasawa

Senji Shirasawa

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
14890
World Ranking
10178
National Ranking
683

Senji Shirasawa publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Senji Shirasawa sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 222 publications — 58th percentile

58% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Senji Shirasawa D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Senji Shirasawa sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 63 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Senji Shirasawa is affiliated with Fukuoka University in Japan and has a research focus primarily in biochemistry, genetics, and molecular biology, with additional contributions in the field of medicine.

Their work spans several subfields, including molecular biology, oncology, cancer research, immunology, and epidemiology. The main topics covered in their research portfolio address areas such as cancer, hypoxia, and metabolism; cancer-related molecular pathways; genomics and chromatin dynamics; PI3K/AKT/mTOR signaling in cancer; colorectal cancer treatments and studies; chromosomal and genetic variations; and epigenetics and DNA methylation.

Recent publications authored or co-authored by Senji Shirasawa include the following:

  • In Colorectal Cancer Cells With Mutant KRAS, SLC25A22-Mediated Glutaminolysis Reduces DNA Demethylation to Increase WNT Signaling, Stemness, and Drug Resistance (2020, Gastroenterology)
  • Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1 (2021, Molecular Oncology)
  • Epipharyngeal Abrasive Therapy (EAT) Has Potential as a Novel Method for Long COVID Treatment (2022, Viruses)
  • Targeting the KRAS oncogene: Synthesis, physicochemical and biological evaluation of novel G-Quadruplex DNA binders (2020, European Journal of Pharmaceutical Sciences)
  • Dual blockade of macropinocytosis and asparagine bioavailability shows synergistic anti-tumor effects on KRAS-mutant colorectal cancer (2021, Cancer Letters)

Frequently collaborating researchers include Toshiyuki Tsunoda (19 joint works), Kensuke Nishi (9), Shuhei Ishikura (8), Kazumasa Yoshida (6), and Kazuhiko Nakabayashi (5).

The scientist's work has been published across a variety of venues, with the highest number of publications appearing in Anticancer Research (8). Other frequent publication venues include Nucleic Acids Research (2), Frontiers in Oncology (2), Journal of Biological Chemistry (2), and Gastroenterology (1).

Best Publications

  • Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.

    J. Rak;Y. Mitsuhashi;L. Bayko;J. Filmus

  • Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

    Senji Shirasawa;Masanori Furuse;Nobuhiko Yokoyama;Takehiko Sasazuki

  • Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis.

    Joanne L. Yu;Linda May;Vladimir Lhotak;Siranoush Shahrzad

  • A functional variant in FCRL3 , encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

    Yuta Kochi;Ryo Yamada;Akari Suzuki;John B. Harley;John B. Harley;John B. Harley

  • Opposing Effects of Ras on p53: Transcriptional Activation of mdm2 and Induction of p19ARF

    Stefan Ries;Carola Biederer;Douglas Woods;Ohad Shifman

  • 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors.

    Qing Bai She;Ensar Halilovic;Qing Ye;Wei Zhen

  • Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus

    Federica Di Nicolantonio;Sabrina Arena;Josep Tabernero;Stefano Grosso

  • Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates

    Leping Cheng;Akiko Arata;Rumiko Mizuguchi;Ying Qian

  • Impact of oncogenes in tumor angiogenesis: Mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

    Futoshi Okada;Janusz W. Rak;Brad St. Croix;Blandine Lieubeau

  • Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes

    Leping Cheng;Omar Abdel Samad;Yi Xu;Rumiko Mizuguchi

  • Identification of susceptibility loci for autoimmune thyroid disease to 5q31–q33 and Hashimoto’s thyroiditis to 8q23–q24 by multipoint affected sib-pair linkage analysis in Japanese

    Kenji Sakai;Senji Shirasawa;Naofumi Ishikawa;Kunihiko Ito

  • Sensitization to the Lysosomal Cell Death Pathway by Oncogene-Induced Down-regulation of Lysosome-Associated Membrane Proteins 1 and 2

    Nicole Fehrenbacher;Lone Bastholm;Thomas Kirkegaard-Sørensen;Bo Rafn

  • Competition between human cells by entosis.

    Qiang Sun;Tianzhi Luo;Yixin Ren;Oliver Florey

  • Inhibition of interferon gamma signaling by the short chain fatty acid butyrate.

    Lidija Klampfer;Jie Huang;Takehiko Sasazuki;Senji Shirasawa

  • Enx (Hox11L1)-deficient mice develop myenteric neuronal hyperplasia and megacolon

    Senji Shirasawa;Anne Marie R. Yunker;Kevin A. Roth;Gary A. Brown

  • BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study

    Eleni Makrodouli;Eftychia Oikonomou;Michal Koc;Ladislav Andera

  • Oncogenic K-RAS is required to maintain changes in cytoskeletal organization, adhesion, and motility in colon cancer cells.

    Claire B. Pollock;Senji Shirasawa;Takehiko Sasazuki;Walter Kolch

  • Formation of brainstem (nor)adrenergic centers and first-order relay visceral sensory neurons is dependent on homeodomain protein Rnx/Tlx3.

    Ying Qian;Bernd Fritzsch;Senji Shirasawa;Chih-Li Chen

  • Rnx deficiency results in congenital central hypoventilation

    Senji Shirasawa;Akiko Arata;Hiroshi Onimaru;Kevin A. Roth

  • Involvement of deregulated epiregulin expression in tumorigenesis in vivo through activated Ki-Ras signaling pathway in human colon cancer cells.

    Iwai Baba;Senji Shirasawa;Ryo Iwamoto;Koji Okumura

Frequent Co-Authors

Takehiko Sasazuki
Takehiko Sasazuki Kyushu University
Kazuhiko Nakabayashi
Kazuhiko Nakabayashi National Center For Child Health and Development
Ken Yamamoto
Ken Yamamoto Kurume University
Satoshi Sasaki
Satoshi Sasaki University of Tokyo
Hidenao Fukuyama
Hidenao Fukuyama Kyoto University
Hiroshi Onimaru
Hiroshi Onimaru Showa University
Qiufu Ma
Qiufu Ma Harvard University
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
John B. Harley
John B. Harley United States Department of Veterans Affairs
Francesco Cognetti
Francesco Cognetti Sapienza University of Rome

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