2026 Takehiko Sasazuki: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	National Ranking	Publications	Citations
Immunology	101	696	21	509	41847
Genetics	102	701	21	443	41595
Medicine	102	7605	182	509	42457

Research.com Recognitions

2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Takehiko Sasazuki was affiliated with Kyushu University in Japan. Their research spanned multiple fields primarily within medicine, biochemistry, genetics, and molecular biology, with a strong focus on immunology and microbiology.

The scientist contributed to several main topics throughout their career, including:

Immunotherapy and Immune Responses
Cancer, Hypoxia, and Metabolism
Cellular transport and secretion
Ubiquitin and proteasome pathways
T-cell and B-cell Immunology
Systemic Lupus Erythematosus Research
Heat shock proteins research

Takehiko Sasazuki published research across various subfields such as immunology, cell biology, molecular biology, immunology and allergy, and cancer research.

Their recent papers reflected a focus on immune mechanisms, cancer biology, and antigen recognition. Notable publications include:

"Dual blockade of macropinocytosis and asparagine bioavailability shows synergistic anti-tumor effects on KRAS-mutant colorectal cancer" (2021, Cancer Letters)
"Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules" (2022, Science Advances)
"Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90" (2020, Frontiers in Oncology)
"Downregulation of HLA class II is associated with relapse after allogeneic stem cell transplantation and alters recognition by antigen-specific T cells" (2022, International Journal of Hematology)
"Contributions of the N-terminal flanking residues of an antigenic peptide from the Japanese cedar pollen allergen Cry j 1 to the T-cell activation by HLA-DP5" (2023, International Immunology)

Frequent collaborators in Sasazuki's research included:

Hisashi Arase
Senji Shirasawa
Hui Jin
Ken Yamamoto
Hiroshi Hamana

Publications appeared in a range of specialized venues illustrating the cross-disciplinary engagement, including:

Cancer Letters
Science Advances
Frontiers in Oncology
International Journal of Hematology
International Immunology

Best Publications

Nomenclature for factors of the HLA system, 2010.

S G. E. Marsh;E. D. Albert;W. F. Bodmer;R. E. Bontrop

3915
Citations
Nomenclature for factors of the HLA system, 1995

J G Bodmer;S G Marsh;Albert;W F Bodmer

1648
Citations
Nomenclature for factors of the HLA system, 1994

Julia G. Bodmer;Steven G. E. Marsh;Ekkehard D. Albert;Walter F. Bodmer

1503
Citations
Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.

J. Rak;Y. Mitsuhashi;L. Bayko;J. Filmus

1048
Citations
Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

Senji Shirasawa;Masanori Furuse;Nobuhiko Yokoyama;Takehiko Sasazuki

954
Citations
Nomenclature for factors of the HLA system, 2004

Steven G.E. Marsh;E. D. Albert;W. F. Bodmer;R. E. Bontrop

832
Citations
Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy

Akinori Kimura;Haruhito Harada;Jeong-Euy Park;Hirofumi Nishi

736
Citations
The clinical significance of human leukocyte antigen (HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched unrelated donors.

Yasuo Morishima;Takehiko Sasazuki;Hidetoshi Inoko;Takeo Juji

666
Citations
Effect of matching of class I HLA alleles on clinical outcome after transplantation of hematopoietic stem cells from an unrelated donor

Takehiko Sasazuki;Takeo Juji;Yasuo Morishima;Naoko Kinukawa

663
Citations
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

Yoshinori Fukui;Osamu Hashimoto;Osamu Hashimoto;Terukazu Sanui;Takamasa Oono

658
Citations
Modulation of TNF-α-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-α production and facilitates viral entry

Shiori Haga;Norio Yamamoto;Chikako Nakai-Murakami;Yoshiaki Osawa

555
Citations
A functional variant in FCRL3 , encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

Yuta Kochi;Ryo Yamada;Akari Suzuki;John B. Harley;John B. Harley;John B. Harley

487
Citations
Nomenclature for factors of the HLA system, 1991. WHO Nomenclature Committee for factors of the HLA system.

Bodmer Jg;Marsh Sg;Albert Ed;Bodmer Wf

478
Citations
Opposing Effects of Ras on p53: Transcriptional Activation of mdm2 and Induction of p19ARF

Stefan Ries;Carola Biederer;Douglas Woods;Ohad Shifman

468
Citations
4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors.

Qing Bai She;Ensar Halilovic;Qing Ye;Wei Zhen

464
Citations
Nomenclature for factors of the HLA system, 1996

Julia G. Bodmer;Steven G.E. Marsh;Steven G.E. Marsh;Ekkehard D. Albert;Walter F. Bodmer

437
Citations
Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients.

Hiroki Nagase;Hiroki Nagase;Yasuo Miyoshi;Akira Horii;Takahisa Aoki

437
Citations
Nomenclature for factors of the HLA system, 1991.

J G Bodmer;S G Marsh;Albert;W F Bodmer

437
Citations
Nomenclature for factors of the HLA system, 2002

Steven G. E. Marsh;Ekkehard D. Albert;Walter F. Bodmer;Ronald E. Bontrop

426
Citations
Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus

Federica Di Nicolantonio;Sabrina Arena;Josep Tabernero;Stefano Grosso

402
Citations
Nomenclature for factors of the HLA system, 2004.

Unknown

16
Citations

Frequent Co-Authors

Senji Shirasawa Fukuoka University

Akinori Kimura Tokyo Medical and Dental University

Yoshinori Fukui Kyushu University

Ken Yamamoto Kurume University

Yasuo Morishima Aichi Medical University

Hidetoshi Inoko Tokai University

Yasuharu Nishimura Kumamoto University

Peter Parham Stanford University

Bernard Mach University of Geneva

Steven G.E. Marsh University College London

External Links

Personal website of Takehiko Sasazuki

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