World's Best Scientists 2026 revealed!
Hiroyuki Mano

Hiroyuki Mano

D-Index & Metrics

Biology and Biochemistry

D-Index
87
Citations
37249
World Ranking
2776
National Ranking
173

Medicine

D-Index
87
Citations
37153
World Ranking
13450
National Ranking
399

Hiroyuki Mano publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hiroyuki Mano sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 385 publications — 89th percentile

89% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Hiroyuki Mano D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroyuki Mano sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 87 D-Index — 86th percentile

86% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Hiroyuki Mano is affiliated with the University of Tokyo in Japan and has focused their research primarily in the fields of Medicine, and Biochemistry, Genetics and Molecular Biology. Their work spans subfields including Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Cancer Research, and Pathology and Forensic Medicine.

The scientist's research topics concentrate on Cancer Genomics and Diagnostics, Cancer Immunotherapy and Biomarkers, Lung Cancer Treatments and Mutations, Sarcoma Diagnosis and Treatment, RNA modifications and cancer, Genetic factors in colorectal cancer, and Colorectal Cancer Treatments and Studies.

Recent significant papers authored or co-authored by Hiroyuki Mano include:

  • The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies, 2020, Nature Immunology
  • Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments, 2022, Cancer Cell
  • An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells, 2020, Immunity
  • C-CAT: The National Datacenter for Cancer Genomic Medicine in Japan, 2022, Cancer Discovery
  • Immune evasion through mitochondrial transfer in the tumour microenvironment, 2025, Nature

Hiroyuki Mano collaborates frequently with several researchers including Shinji Kohsaka, Toshihide Ueno, Masahito Kawazu, Shinya Kojima, and Masachika Ikegami. These collaborations reflect an extensive network in cancer-related research.

The scientist has published in multiple venues, with the most frequent being Cancer Science, Cancer Research, npj Precision Oncology, Nature, and Clinical Cancer Research. These publication sites correspond with the main and subfields of their research interest.

Best Publications

  • Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer

    Manabu Soda;Young Lim Choi;Munehiro Enomoto;Shuji Takada

  • RET, ROS1 and ALK fusions in lung cancer.

    Kengo Takeuchi;Manabu Soda;Yuki Togashi;Ritsuro Suzuki

  • EML4-ALK Mutations in Lung Cancer That Confer Resistance to ALK Inhibitors

    Young Lim Choi;Manabu Soda;Yoshihiro Yamashita;Toshihide Ueno

  • Oncogenic mutations of ALK kinase in neuroblastoma.

    Yuyan Chen;Junko Takita;Young Lim Choi;Motohiro Kato

  • KIF5B-ALK, a Novel Fusion Oncokinase Identified by an Immunohistochemistry-based Diagnostic System for ALK-positive Lung Cancer

    Kengo Takeuchi;Young Lim Choi;Yuki Togashi;Manabu Soda

  • A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner.

    R Sakai;A Iwamatsu;N Hirano;S Ogawa

  • The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies.

    Shogo Kumagai;Yosuke Togashi;Takahiro Kamada;Eri Sugiyama

  • A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer.

    King Pan Ng;Axel M Hillmer;Charles T H Chuah;Charles T H Chuah;Wen Chun Juan

  • A mouse model for EML4-ALK-positive lung cancer

    Manabu Soda;Shuji Takada;Kengo Takeuchi;Young Lim Choi

  • Multiplex Reverse Transcription-PCR Screening for EML4-ALK Fusion Transcripts

    Kengo Takeuchi;Young Lim Choi;Manabu Soda;Kentaro Inamura

  • Correction: Corrigendum: Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

    Osamu Hashizume;Sakiko Ohnishi;Takayuki Mito;Akinori Shimizu

  • EML4-ALK Fusion Is Linked to Histological Characteristics in a Subset of Lung Cancers

    Kentaro Inamura;Kengo Takeuchi;Yuki Togashi;Kimie Nomura

  • Identification of Novel Isoforms of the EML4-ALK Transforming Gene in Non–Small Cell Lung Cancer

    Young Lim Choi;Kengo Takeuchi;Manabu Soda;Kentaro Inamura

  • EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset.

    Kentaro Inamura;Kengo Takeuchi;Yuki Togashi;Satoko Hatano

  • Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.

    K. Mitani;S. Ogawa;T. Tanaka;H. Miyoshi

  • In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents

    Yasuhiko Kano;Miyuki Akutsu;Saburo Tsunoda;Hiroyuki Mano

  • Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis

    Eugene Berezikov;Geert van Tetering;Mark Verheul;Jose van de Belt

  • MCPIP1 Ribonuclease Antagonizes Dicer and Terminates MicroRNA Biogenesis through Precursor MicroRNA Degradation

    Hiroshi I. Suzuki;Mayu Arase;Hironori Matsuyama;Young Lim Choi

  • Array-based genomic resequencing of human leukemia

    Y Yamashita;J Yuan;I Suetake;H Suzuki

  • Non-solid oncogenes in solid tumors : EML4-ALK fusion genes in lung cancer

    Hiroyuki Mano

Frequent Co-Authors

Kazuyuki Shimada
Kazuyuki Shimada Nagoya University
Uichi Ikeda
Uichi Ikeda Shinshu University
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Hisamaru Hirai
Hisamaru Hirai University of Tokyo
Keiya Ozawa
Keiya Ozawa Jichi Medical University
Yoshio Yazaki
Yoshio Yazaki University of Tokyo
Kohei Miyazono
Kohei Miyazono University of Tokyo
Seishi Ogawa
Seishi Ogawa Kyoto University
Yusuke Furukawa
Yusuke Furukawa Jichi Medical University
Fumimaro Takaku
Fumimaro Takaku University of Tokyo

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Hiroyuki Mano

Trending Scientists

Recently Published Articles