Hisamaru Hirai

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Best Publications

• Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis

  Masataka Sata;Akio Saiura;Atsushi Kunisato;Akihiro Tojo

  1725
  Citations

• Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis

  Nicholas W Gale;Sacha J Holland;David M Valenzuela;Ann Flenniken

  1068
  Citations

• AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis.

  Motoshi Ichikawa;Takashi Asai;Toshiki Saito;Go Yamamoto

  711
  Citations

• Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development.

  Toshiki Saito;Shigeru Chiba;Motoshi Ichikawa;Atsushi Kunisato

  694
  Citations

• A novel putative tyrosine kinase receptor encoded by the eph gene

  Hisamaru Hirai;Yoshiro Maru;Koichi Hagiwara;Junji Nishida

  638
  Citations

• Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases.

  K Vuori;H Hirai;S Aizawa;E Ruoslahti

  626
  Citations

• Notch1 but Not Notch2 Is Essential for Generating Hematopoietic Stem Cells from Endothelial Cells

  Keiki Kumano;Shigeru Chiba;Atsushi Kunisato;Masataka Sata

  573
  Citations

• Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.

  Masashi Sanada;Takahiro Suzuki;Lee-Yung Shih;Makoto Otsu

  476
  Citations

• F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation.

  Qi Dong Hu;Qi Dong Hu;Beng Ti Ang;Beng Ti Ang;Meliha Karsak;Wei Ping Hu

  455
  Citations

• The oncoprotein Evi-1 represses TGF-Beta signalling by inhibiting Smad3

  Mineo Kurokawa;Kinuko Mitani;Kenji Irie;Tomohiro Matsuyama

  444
  Citations

• Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.

  K. Mitani;S. Ogawa;T. Tanaka;H. Miyoshi

  441
  Citations

• Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas.

  Hiroaki Honda;Hideaki Oda;Tetsuya Nakamoto;Zen-ichiro Honda

  432
  Citations

• Delta1-Notch3 Interactions Bias the Functional Differentiation of Activated CD4+ T Cells

  Yoichi Maekawa;Shin-ichi Tsukumo;Shigeru Chiba;Hisamaru Hirai

  417
  Citations

• Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases.

  Bruce J. Mayer;Hisamaru Hirai;Ryuichi Sakai

  416
  Citations

• Prospective Comparison of the Diagnostic Potential of Real-Time PCR, Double-Sandwich Enzyme-Linked Immunosorbent Assay for Galactomannan, and a (1→3)-β-d-Glucan Test in Weekly Screening for Invasive Aspergillosis in Patients with Hematological Disorders

  Masahito Kawazu;Yoshinobu Kanda;Yasuhito Nannya;Katsunori Aoki

  406
  Citations

• Integrin-mediated Cell Adhesion Promotes Tyrosine Phosphorylation of p130Cas, a Src Homology 3-containing Molecule Having Multiple Src Homology 2-binding Motifs

  Yoshihisa Nojima;Noritsugu Morino;Toshihide Mimura;Ken Hamasaki

  385
  Citations

• Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone

  Toshimasa Yamauchi;Kohjiro Ueki;Kazuyuki Tobe;Hiroyuki Tamemoto

  382
  Citations

• Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

  Kiyoshi Shimizu;Shigeru Chiba;Keiki Kumano;Noriko Hosoya

  356
  Citations

• Use of Real-Time PCR on Blood Samples for Diagnosis of Invasive Aspergillosis

  Masahiro Kami;Takafumi Fukui;Seishi Ogawa;Yukimasa Kazuyama

  348
  Citations

• Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia

  H Miyoshi;M Ohira;K Shimizu;K Mitani

  337
  Citations