What is he best known for?
The fields of study he is best known for:
- Gene
- Cancer
- Internal medicine
Hisamaru Hirai mostly deals with Cell biology, Molecular biology, Cancer research, Immunology and Haematopoiesis.
His Cell biology study which covers Cellular differentiation that intersects with Marginal zone.
His studies in Molecular biology integrate themes in fields like Gene, Chromosomal translocation, Binding domain, Alternative splicing and Runt.
His Cancer research research incorporates themes from Tyrosine kinase, Tyrosine phosphorylation, Tumor suppressor gene, Leukemia and Acute lymphocytic leukemia.
In his study, Cardiology is strongly linked to Internal medicine, which falls under the umbrella field of Immunology.
His Haematopoiesis research is multidisciplinary, relying on both Myeloid, Cytokine, Bone marrow and Progenitor cell.
His most cited work include:
- Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis (1072 citations)
- Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis (774 citations)
- AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis. (515 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Molecular biology, Cancer research, Cell biology, Immunology and Internal medicine.
Hisamaru Hirai works mostly in the field of Molecular biology, limiting it down to topics relating to Gene and, in certain cases, DNA.
Hisamaru Hirai interconnects Chronic myelogenous leukemia, Leukemia, Haematopoiesis and ABL in the investigation of issues within Cancer research.
His Haematopoiesis study combines topics from a wide range of disciplines, such as Myeloid and Progenitor cell.
Many of his studies on Cell biology apply to Cellular differentiation as well.
His Immunology study frequently links to related topics such as Stem cell.
He most often published in these fields:
- Molecular biology (31.86%)
- Cancer research (23.30%)
- Cell biology (21.83%)
What were the highlights of his more recent work (between 2003-2013)?
- Internal medicine (16.22%)
- Cell biology (21.83%)
- Transplantation (7.37%)
In recent papers he was focusing on the following fields of study:
Hisamaru Hirai mainly investigates Internal medicine, Cell biology, Transplantation, Cancer research and Haematopoiesis.
His Internal medicine study incorporates themes from Gastroenterology and Surgery.
His Cell biology study focuses on RUNX1 in particular.
His Cancer research research is multidisciplinary, incorporating perspectives in Cellular differentiation, CD135, Receptor tyrosine kinase, Progenitor cell and Chronic myelogenous leukemia.
Hisamaru Hirai has researched Haematopoiesis in several fields, including Immunology, Myeloid, Cytokine, K562 cells and Transformation.
His work carried out in the field of Transcription factor brings together such families of science as Molecular biology, Leukemia and Signal transduction.
Between 2003 and 2013, his most popular works were:
- AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis. (515 citations)
- Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms. (339 citations)
- Prospective Comparison of the Diagnostic Potential of Real-Time PCR, Double-Sandwich Enzyme-Linked Immunosorbent Assay for Galactomannan, and a (1→3)-β-d-Glucan Test in Weekly Screening for Invasive Aspergillosis in Patients with Hematological Disorders (259 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Cancer
- Internal medicine
His primary scientific interests are in Cancer research, Haematopoiesis, Cell biology, RUNX1 and Transcription factor.
His work deals with themes such as Progenitor cell, Tyrosine kinase and Cytokine, which intersect with Cancer research.
Haematopoiesis is frequently linked to Leukemia in his study.
Hisamaru Hirai specializes in Cell biology, namely Lymphocyte homing receptor.
His Corepressor research is multidisciplinary, incorporating elements of Carcinogenesis, Molecular biology, Transcriptional regulation and DNA-binding protein.
Myeloid is a subfield of Immunology that Hisamaru Hirai explores.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
