2012 - Fellow of the American Association for the Advancement of Science (AAAS)
His primary areas of investigation include Voltage-dependent anion channel, Biophysics, Voltage-Dependent Anion Channel 1, Biochemistry and VDAC3. His Voltage-dependent anion channel study incorporates themes from Translocase of the inner membrane, Membrane and Mitochondrion, Cell biology. The study incorporates disciplines such as Liposome and Membrane potential in addition to Membrane.
The various areas that Marco Colombini examines in his Cell biology study include Intermembrane space, Mitochondrial carrier and Mitochondrial intermembrane space. As part of the same scientific family, he usually focuses on Voltage-Dependent Anion Channel 1, concentrating on VDAC2 and intersecting with Lipid bilayer and VDAC1. His Biochemistry research focuses on Gating and how it connects with Mitochondrial channel.
Voltage-dependent anion channel, Biophysics, Membrane, Bacterial outer membrane and Biochemistry are his primary areas of study. While the research belongs to areas of Voltage-dependent anion channel, he spends his time largely on the problem of Voltage-Dependent Anion Channel 1, intersecting his research to questions surrounding VDAC3 and VDAC2. His work in Biophysics tackles topics such as Protein structure which are related to areas like Stereochemistry.
Marco Colombini has included themes like Chromatography and Analytical chemistry in his Membrane study. His work deals with themes such as Membrane protein, Liposome and Mitochondrion, which intersect with Bacterial outer membrane. Mitochondrion is a subfield of Cell biology that he studies.
Marco Colombini mainly investigates Biophysics, Membrane, Ceramide, Cell biology and Bacterial outer membrane. His Biophysics study integrates concerns from other disciplines, such as Crystallography, Biochemistry, Membrane channel and Voltage-dependent anion channel. In Membrane, Marco Colombini works on issues like Nanotechnology, which are connected to Budding.
His studies deal with areas such as Sphingolipid, Cell membrane, Bcl-xL, Lipid bilayer and Mitochondrion as well as Ceramide. In the subject of general Cell biology, his work in Mitochondrial apoptosis-induced channel is often linked to AMP-activated protein kinase, thereby combining diverse domains of study. His study focuses on the intersection of Bacterial outer membrane and fields such as Protein structure with connections in the field of Ion transporter.
Marco Colombini focuses on Cell biology, Mitochondrion, Bacterial outer membrane, Ceramide and Membrane. His Cell biology study also includes fields such as
His Voltage-dependent anion channel research is multidisciplinary, relying on both Flux and Gating. His work in Ceramide covers topics such as Sphingolipid which are related to areas like Mitochondrial intermembrane space. His Membrane study frequently draws connections to adjacent fields such as Biophysics.
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Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.
Sebastian Hiller;Robert G. Garces;Thomas J. Malia;Vladislav Y. Orekhov;Vladislav Y. Orekhov.
Science (2008)
Reconstitution in planar lipid bilayers of a voltage-dependent anion-selective channel obtained from paramecium mitochondria.
Stanley J. Schein;Marco Colombini;Alan Finkelstein.
The Journal of Membrane Biology (1976)
A candidate for the permeability pathway of the outer mitochondrial membrane
M. Colombini.
Nature (1979)
VDAC: The channel at the interface between mitochondria and the cytosol
Marco Colombini.
Molecular and Cellular Biochemistry (2004)
Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival
Matthew G. Vander Heiden;Navdeep S. Chandel;Xiao Xian Li;Paul T. Schumacker.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes
Bruce L. Kagan;Alan Finkelstein;Marco Colombini.
Proceedings of the National Academy of Sciences of the United States of America (1981)
Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane.
Matthew G. Vander Heiden;Xiao Xian Li;Eyal Gottleib;R. Blake Hill.
Journal of Biological Chemistry (2001)
Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins.
Leah J. Siskind;Richard N. Kolesnick;Marco Colombini.
Journal of Biological Chemistry (2002)
VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function.
T. Rostovtseva;M. Colombini.
Biophysical Journal (1997)
The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis.
Leah J. Siskind;Marco Colombini.
Journal of Biological Chemistry (2000)
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