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Immunology

D-Index
70
Citations
13394
World Ranking
2456
National Ranking
1175

Overview

Alan L. Epstein is affiliated with the University of Southern California in the United States. Their research spans several interconnected fields with a primary focus on Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology.

Epstein's subfields of study include Immunology, Oncology, Molecular Biology, Cancer Research, and Radiology, Nuclear Medicine and Imaging. The core topics they have explored involve Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, Immune Cell Function and Interaction, Immune cells in cancer, Monoclonal and Polyclonal Antibodies Research, T-cell and B-cell Immunology, and RNA Interference and Gene Delivery.

Frequent co-authors collaborating with Epstein include Leslie A. Khawli, Peisheng Hu, Vyshnavi Pachipulusu, Aida Kouhi, and Long Zheng.

Epstein has published multiple articles across various respected venues. Their recent papers include:

  • Principles of N-Linked Glycosylation Variations of IgG-Based Therapeutics: Pharmacokinetic and Functional Considerations, 2020, published in Antibodies
  • Brain Disposition of Antibody-Based Therapeutics: Dogma, Approaches and Perspectives, 2021, in International Journal of Molecular Sciences
  • Eliciting anti-cancer immunity by genetically engineered multifunctional exosomes, 2022, in Molecular Therapy
  • Targeting macrophages for enhancing CD47 blockade-elicited lymphoma clearance and overcoming tumor-induced immunosuppression, 2022, in Blood
  • Molecular profiling reveals a hypoxia signature in breast implant-associated anaplastic large cell lymphoma, 2020, in Haematologica

Publications by Epstein frequently appear in venues such as The American Journal of Gastroenterology, Neuro-Oncology, The Journal of Immunology, Journal of Neurosurgery, and Cancer Research.

Best Publications

  • Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells

    Melissa G. Lechner;Daniel J. Liebertz;Alan L. Epstein

  • Anaplastic large cell lymphoma occurring in women with breast implants: analysis of 173 cases.

    Garry S. Brody;Dennis Deapen;Clive R. Taylor;Lauren Pinter-Brown

  • Immunogenicity of murine solid tumor models as a defining feature of in vivo behavior and response to immunotherapy.

    Melissa G. Lechner;Saman S. Karimi;Keegan Barry-Holson;Trevor E. Angell

  • Functional characterization of human Cd33+ And Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines

    Melissa G Lechner;Carolina Megiel;Sarah M Russell;Brigid Bingham

  • Biology of the human malignant lymphomas. IV. Functional characterization of ten diffuse histiocytic lymphoma cell lines

    Alan L. Epstein;Ronald Levy;Hun Kim;Werner Henle

  • Detection of necrotic malignant tissue and associated therapy

    Alan L. Epstein;Clive R. Taylor

  • Genetically Engineered Cell-Derived Nanoparticles for Targeted Breast Cancer Immunotherapy.

    Xiaojing Shi;Qinqin Cheng;Tianling Hou;Menglu Han

  • Nuclear domain 10 (ND10) associated proteins are also present in nuclear bodies and redistribute to hundreds of nuclear sites after stress.

    Gerd G. Maul;Eunsil Yu;Alexander M. Ishov;Alan L. Epstein

  • Two new monoclonal antibodies, Lym-1 and Lym-2, reactive with human B-lymphocytes and derived tumors, with immunodiagnostic and immunotherapeutic potential.

    Alan L. Epstein;Robert J. Marder;Jane N. Winter;Efstathois Stathopoulos

  • A novel method for the detection of necrotic lesions in human cancers.

    Alan L. Epstein;Feng-Ming Chen;Clive R. Taylor

  • A method for simultaneous nuclear immunofluorescence and DNA content quantitation using monoclonal antibodies and flow cytometry

    Charles V. Clevenger;Kenneth D. Bauer;Alan L. Epstein

  • Biomarkers Provide Clues to Early Events in the Pathogenesis of Breast Implant-Associated Anaplastic Large Cell Lymphoma.

    Marshall E. Kadin;Anand Deva;Haiying Xu;John Morgan

  • Biology of the human malignant lymphomas. I. Establishment in continuous cell culture and heterotransplantation of diffuse histiocytic lymphomas.

    Alan L. Epstein;Henry S. Kaplan

  • Treatment of B cell malignancies with 131I LYM‐1 monoclonal antibodies

    S. J. Denardo;Gerald L Denardo;L. F. O'Grady;E. Hu

  • Enhanced Tumor Uptake of Macromolecules Induced by a Novel Vasoactive Interleukin 2 Immunoconjugate

    Brian LeBerthon;Leslie A. Khawli;Mian Alauddin;Gordon K. Miller

  • Comparative serum stability of radiochelates for antibody radiopharmaceuticals.

    William C. Cole;Sally J. DeNardo;Claude F. Meares;Michael J. McCall

  • Immunohistochemical analysis of human lymphomas with monoclonal antibodies to B cell and Ia antigens reactive in paraffin sections.

    Marder Rj;Variakojis D;Silver J;Epstein Al

  • MHC Class I Loss Is a Frequent Mechanism of Immune Escape in Papillary Thyroid Cancer That Is Reversed by Interferon and Selumetinib Treatment In Vitro

    Trevor E. Angell;Melissa G. Lechner;Julie K. Jang;Jonathan S. LoPresti

  • Pivotal Study of Iodine-131–Labeled Chimeric Tumor Necrosis Treatment Radioimmunotherapy in Patients With Advanced Lung Cancer

    Shaoliang Chen;Like Yu;Changying Jiang;Yan Zhao

  • Modulation of Treg cells/T effector function by GITR signaling is context–dependent

    Amal Ephrem;Alan L. Epstein;Geoffrey L. Stephens;Angela M. Thornton

  • Pretreatment with a Monoclonal Antibody/Interleukin-2 Fusion Protein Directed against DNA Enhances the Delivery of Therapeutic Molecules to Solid Tumors

    Jason L. Hornick;Leslie A. Khawli;Peisheng Hu;Jahangir Sharifi

  • Survival Signals and Targets for Therapy in Breast Implant–Associated ALK− Anaplastic Large Cell Lymphoma

    Melissa G. Lechner;Carolina Megiel;Connor H. Church;Trevor E. Angell

Frequent Co-Authors

Leslie A. Khawli
Leslie A. Khawli University of Southern California
Clive R. Taylor
Clive R. Taylor University of Southern California
Jason L. Hornick
Jason L. Hornick Brigham and Women's Hospital
Charles V. Clevenger
Charles V. Clevenger Virginia Commonwealth University
Bellur S. Prabhakar
Bellur S. Prabhakar University of Illinois at Chicago
Henry S. Kaplan
Henry S. Kaplan Stanford University
L. Jeffrey Medeiros
L. Jeffrey Medeiros The University of Texas MD Anderson Cancer Center
Walter J. Storkus
Walter J. Storkus University of Pittsburgh
Susan Groshen
Susan Groshen University of Southern California
Honggang Cui
Honggang Cui Johns Hopkins University

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