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Immunology

D-Index
51
Citations
15301
World Ranking
4111
National Ranking
273

Overview

Karsten Mahnke is affiliated with Heidelberg University in Germany and has focused their research primarily in the fields of Immunology and Microbiology, as well as Biochemistry, Genetics and Molecular Biology. Their scientific output includes 28 publications in Immunology and Microbiology and 11 in Biochemistry, Genetics and Molecular Biology.

The main subfields of their work include Immunology, Physiology, Molecular Biology, Hematology, and Immunology and Allergy. Their research covers a range of specific topics such as Immune Cell Function and Interaction, Adenosine and Purinergic Signaling, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, Immune Response and Inflammation, Mast cells and histamine, and Cell Adhesion Molecules Research.

Recent publications by Mahnke include:

  • Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells, 2020, Cell
  • The Multifaceted Actions of CD73 During Development and Suppressive Actions of Regulatory T Cells, 2022, Frontiers in Immunology
  • Antigen targeting to dendritic cells: Still a place in future immunotherapy?, 2022, European Journal of Immunology
  • Regulatory T Cells Prevent Neutrophilic Infiltration of Skin during Contact Hypersensitivity Reactions by Strengthening the Endothelial Barrier, 2021, Journal of Investigative Dermatology
  • Adenosine, bridging chronic inflammation and tumor growth, 2023, Frontiers in Immunology

Mahnke has collaborated with several frequent co-authors including Alexander Enk, Hans Christian Probst, Tobias Bopp, Meihong Da, and Sabine Ring.

Their work has been published repeatedly in certain academic venues, among them:

  • European Journal of Immunology
  • Journal of Investigative Dermatology
  • Frontiers in Immunology
  • International Journal of Molecular Sciences
  • Immunology

Best Publications

  • Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo

    Daniel Hawiger;Kayo Inaba;Kayo Inaba;Yair Dorsett;Ming Guo

  • Efficient Targeting of Protein Antigen to the Dendritic Cell Receptor DEC-205 in the Steady State Leads to Antigen Presentation on Major Histocompatibility Complex Class I Products and Peripheral CD8+ T Cell Tolerance

    Laura C Bonifaz;David P. Bonnyay;Karsten Mahnke;Karsten Mahnke;Miguel Rivera

  • Efficient Presentation of Phagocytosed Cellular Fragments on the Major Histocompatibility Complex Class II Products of Dendritic Cells

    Kayo Inaba;Shannon Turley;Fumiya Yamaide;Tomonori Iyoda

  • The Dendritic Cell Receptor for Endocytosis, Dec-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II–Positive Lysosomal Compartments

    Karsten Mahnke;Ming Guo;Sena Lee;Homero Sepulveda

  • Dendritic cell function in vivo during the steady state: a role in peripheral tolerance.

    Ralph M. Steinman;Daniel Hawiger;Kang Liu;Laura Bonifaz

  • Immature, but not inactive: the tolerogenic function of immature dendritic cells

    Karsten Mahnke;Edgar Schmitt;Laura Bonifaz;Alexander H Enk

  • Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells

    Karsten Mahnke;Yingjie Qian;Juergen Knop;Alexander H Enk

  • Ultraviolet-B-induced apoptosis of keratinocytes: evidence for partial involvement of tumor necrosis factor-alpha in the formation of sunburn cells.

    Agatha Schwarz;Ranjit Bhardwaj;Yoshinori Aragane;Karsten Mahnke

  • Depletion of CD4+CD25+ human regulatory T cells in vivo: Kinetics of Treg depletion and alterations in immune functions in vivo and in vitro

    Karsten Mahnke;Kurt Schönfeld;Sabine Fondel;Sabine Ring

  • Pro-opiomelanocortin-derived peptides induce IL-10 production in human monocytes.

    R S Bhardwaj;A Schwarz;E Becher;K Mahnke

  • Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells

    Laura Schaupp;Sabine Muth;Leif Rogell;Michael Kofoed-Branzk

  • The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions.

    Bhardwaj Rs;Zotz C;Zwadlo-Klarwasser G;Roth J

  • Evidence for the differential expression of the functional alpha-melanocyte-stimulating hormone receptor MC-1 on human monocytes.

    R Bhardwaj;E Becher;K Mahnke;M Hartmeyer

  • Tolerogenic dendritic cells and regulatory T cells: A two-way relationship

    Karsten Mahnke;Theron S. Johnson;Sabine Ring;Alexander H. Enk

  • Targeting of Antigens to Activated Dendritic Cells In vivo Cures Metastatic Melanoma in Mice

    Karsten Mahnke;Yingjie Qian;Sabine Fondel;Juergen Brueck

  • alpha-Melanocyte-stimulating hormone induces hapten-specific tolerance in mice.

    S Grabbe;R S Bhardwaj;K Mahnke;M M Simon

  • Dissection of antigenic and irritative effects of epicutaneously applied haptens in mice. Evidence that not the antigenic component but nonspecific proinflammatory effects of haptens determine the concentration-dependent elicitation of allergic contact dermatitis.

    S Grabbe;M Steinert;K Mahnke;A Schwartz

  • Induction of immunosuppressive functions of dendritic cells in vivo by CD4+CD25+ regulatory T cells: role of B7-H3 expression and antigen presentation.

    Karsten Mahnke;Sabine Ring;Theron S. Johnson;Sonja Schallenberg

  • A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells.

    Ming Guo;Schiaoching Gong;Svetlana Maric;Ziva Misulovin

  • Pregnancy‐associated diseases are characterized by the composition of the systemic regulatory T cell (Treg) pool with distinct subsets of Tregs

    A Steinborn;E Schmitt;A Kisielewicz;S Rechenberg

  • Constitutive Crosspresentation of Tissue Antigens by Dendritic Cells Controls CD8+ T Cell Tolerance In Vivo

    Nancy Luckashenak;Samira Schroeder;Katrin Endt;Darja Schmidt

Frequent Co-Authors

Alexander Enk
Alexander Enk Heidelberg University
Thomas Schwarz
Thomas Schwarz Boston Children's Hospital
Stephan Grabbe
Stephan Grabbe Johannes Gutenberg University of Mainz
Stefan Meuer
Stefan Meuer Heidelberg University
Ralph M. Steinman
Ralph M. Steinman Rockefeller University
Martin Zeier
Martin Zeier University Hospital Heidelberg
Edgar Schmitt
Edgar Schmitt Johannes Gutenberg University of Mainz
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
Thomas A. Luger
Thomas A. Luger University of Münster
Hansjörg Schild
Hansjörg Schild Johannes Gutenberg University of Mainz

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