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Biology and Biochemistry

D-Index
58
Citations
10788
World Ranking
13309
National Ranking
5661

Overview

Wanghua Gong is affiliated with Leidos in the United States. Their research primarily spans the fields of Medicine, Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology. Within these areas, their subfields of study include Molecular Biology, Microbiology, Epidemiology, Immunology, and Surgery.

Their recent publications cover a range of topics related to immune response, antimicrobial peptides, and inflammation. Notable papers include:

  • FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis, 2020, Nature Communications
  • The Contribution of Chemoattractant GPCRs, Formylpeptide Receptors, to Inflammation and Cancer, 2020, Frontiers in Endocrinology
  • The potentials of short fragments of human anti-microbial peptide LL-37 as a novel therapeutic modality for diseases, 2021, Frontiers in Bioscience-Landmark
  • A Critical Role of Formyl Peptide Receptors in Host Defense against Escherichia coli, 2020, The Journal of Immunology
  • Distinct contributions of cathelin-related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis, 2020, The Journal of Pathology

Frequent collaborators in Wanghua Gong's work include Keqiang Chen, Teizo Yoshimura, Jiaqiang Huang, Jiming Wang, and Giorgio Trinchieri.

Publications by Wanghua Gong are often found in journals such as the International Journal of Molecular Sciences, Gut Pathogens, Microorganisms, Nature Communications, and Frontiers in Endocrinology.

The main research topics addressed by Wanghua Gong encompass:

  • Antimicrobial Peptides and Activities
  • Immune Response and Inflammation
  • S100 Proteins and Annexins
  • Helicobacter pylori-related gastroenterology studies
  • Gut microbiota and health
  • HIV Research and Treatment
  • Pneumonia and Respiratory Infections

Best Publications

  • A Seven-transmembrane, G Protein–coupled Receptor, FPRL1, Mediates the Chemotactic Activity of Serum Amyloid A for Human Phagocytic Cells

    Shao Bo Su;Wanghua Gong;Ji Liang Gao;Weiping Shen

  • Human recombinant monocyte chemotactic protein and other C-C chemokines bind and induce directional migration of dendritic cells in vitro.

    Luo Ling Xu;M. K. Warren;W. L. Rose;W. Gong

  • Toll-like receptors in inflammation, infection and cancer.

    Keqiang Chen;Jian Huang;Wanghua Gong;Pablo Iribarren

  • Chemokines and their role in tumor growth and metastasis.

    Ji Ming Wang;Xiyun Deng;Wanghua Gong;Shaobo Su

  • Amyloid β42 Activates a G-Protein-Coupled Chemoattractant Receptor, FPR-Like-1

    Yingying Le;Wanghua Gong;H. Lee Tiffany;Alexei Tumanov

  • The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines

    Bao Qun Li;Tao Fu;Wang-Hua Gong;Nancy Dunlop

  • Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor.

    Guoguang Ying;Pablo Iribarren;Ye Zhou;Wanghua Gong

  • Activation of Toll-like Receptor 2 on Microglia Promotes Cell Uptake of Alzheimer Disease-associated Amyloid β Peptide

    Keqiang Chen;Pablo Iribarren;Jinyue Hu;Jianhong Chen

  • Utilization of Two Seven-Transmembrane, G Protein-Coupled Receptors, Formyl Peptide Receptor-Like 1 and Formyl Peptide Receptor, by the Synthetic Hexapeptide WKYMVm for Human Phagocyte Activation

    Yingying Le;Wanghua Gong;Baoqun Li;Nancy M. Dunlop

  • Phenotypic and functional change of cytokine-activated neutrophils: inflammatory neutrophils are heterogeneous and enhance adaptive immune responses

    Shigeo Yamashiro;Hidenobu Kamohara;Ji Ming Wang;De Yang

  • Beta amyloid peptide (Abeta42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages.

    Hiroshi Yazawa;Zu-Xi Yu;Takeda;Yingying Le

  • The neurotoxic prion peptide fragment PrP(106-126) is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1.

    Yingying Le;Hiroshi Yazawa;Wanghua Gong;Zuxi Yu

  • Monocyte Chemotactic Protein-2 (MCP-2) Uses CCR1 AND CCR2B as Its Functional Receptors

    Xiaoqi Gong;Wanghua Gong;Douglas B. Kuhns;Adit Ben-Baruch

  • A synthetic peptide derived from human immunodeficiency virus type 1 gp120 downregulates the expression and function of chemokine receptors CCR5 and CXCR4 in monocytes by activating the 7-transmembrane G-protein-coupled receptor FPRL1/LXA4R.

    Xiyun Deng;Hirotsugu Ueda;Hirotsugu Ueda;Shao Bo Su;Shao Bo Su;Wanghua Gong;Wanghua Gong

  • Expression of CCR6 and CD83 by cytokine-activated human neutrophils.

    Shigeo Yamashiro;Ji-Ming Wang;De Yang;Wang-Hua Gong

  • Monocyte Chemotactic Protein-2 Activates CCR5 and Blocks CD4/CCR5-mediated HIV-1 Entry/Replication

    Wanghua Gong;O.M. Zack Howard;Jim A. Turpin;Michael C. Grimm

  • Chemokines in homeostasis and diseases.

    Keqiang Chen;Zhiyao Bao;Zhiyao Bao;Peng Tang;Peng Tang;Wanghua Gong

  • Formylpeptide Receptor FPR and the Rapid Growth of Malignant Human Gliomas

    Ye Zhou;Xiuwu Bian;Yingying Le;Wanghua Gong

  • Bacterial Lipopolysaccharide Selectively Up-Regulates the Function of the Chemotactic Peptide Receptor Formyl Peptide Receptor 2 in Murine Microglial Cells

    You-Hong Cui;Yingying Le;Wanghua Gong;Paul Proost

  • Cutting Edge: A Critical Role for the G Protein-Coupled Receptor mFPR2 in Airway Inflammation and Immune Responses

    Keqiang Chen;Keqiang Chen;Yingying Le;Ying Liu;Wanghua Gong

Frequent Co-Authors

Ji Ming Wang
Ji Ming Wang National Institutes of Health
Yingying Le
Yingying Le Chinese Academy of Sciences
Xiu-Wu Bian
Xiu-Wu Bian Third Military Medical University
Philip M. Murphy
Philip M. Murphy National Institutes of Health
Joost J. Oppenheim
Joost J. Oppenheim National Institutes of Health
Lino Tessarollo
Lino Tessarollo National Institutes of Health
Thomas J. Rogers
Thomas J. Rogers Temple University
Teizo Yoshimura
Teizo Yoshimura Okayama University
Paul Proost
Paul Proost KU Leuven
O. M. Zack Howard
O. M. Zack Howard National Institutes of Health

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