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Neuroscience

D-Index
60
Citations
27273
World Ranking
3755
National Ranking
1718

Overview

Wen-Biao Gan is affiliated with New York University in the United States. Their primary research field is Neuroscience, with a focus on several subfields including Cellular and Molecular Neuroscience, Cognitive Neuroscience, Neurology, Molecular Biology, and Physiology. This range reflects an interdisciplinary approach covering diverse aspects of brain function and neurological processes.

Their recent research contributions include multiple publications addressing topics from neural dynamics to neuroinflammation. Notable recent papers include:

  • "Forty-hertz light stimulation does not entrain native gamma oscillations in Alzheimer's disease model mice" (2023, Nature Neuroscience)
  • "REM sleep promotes experience-dependent dendritic spine elimination in the mouse cortex" (2020, Nature Communications)
  • "A fast genetically encoded fluorescent sensor for faithful in vivo acetylcholine detection in mice, fish, worms and flies" (2020, bioRxiv [Cold Spring Harbor Laboratory])
  • "BDNF produced by cerebral microglia promotes cortical plasticity and pain hypersensitivity after peripheral nerve injury" (2021, PLoS Biology)
  • "Specific depletion of resident microglia in the early stage of stroke reduces cerebral ischemic damage" (2021, Journal of Neuroinflammation)

These papers illustrate research themes including neurodegeneration, plasticity, neuroinflammation, and neural signaling mechanisms associated with both disease models and normal brain function.

Wen-Biao Gan frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Alzheimer's & Dementia, Nature Neuroscience, and PLoS Biology. This indicates active engagement in well-established journals in neuroscience and related biomedical sciences.

Their main research topics cover:

  • Neuroscience and Neuropharmacology Research
  • Photoreceptor and Optogenetics Research
  • Neural Dynamics and Brain Function
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's Disease Research and Treatments
  • Sleep and Wakefulness Research
  • Memory and Neural Mechanisms

Collaborative efforts are evident through repeated coauthorship with researchers including Yang Bai, Zongyue Cheng, Xujun Wu, Alejandro Martín-Ávila, and Guang Yang, which suggests sustained research partnerships.

Best Publications

  • ATP mediates rapid microglial response to local brain injury in vivo

    Dimitrios Davalos;Jaime Grutzendler;Jaime Grutzendler;Guang Yang;Jiyun V Kim

  • Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

    Christopher N. Parkhurst;Guang Yang;Ipe Ninan;Jeffrey N. Savas

  • The P2Y12 receptor regulates microglial activation by extracellular nucleotides

    Sharon E Haynes;Gunther Hollopeter;Gunther Hollopeter;Guang Yang;Dana Kurpius

  • Long-term dendritic spine stability in the adult cortex

    Jaime Grutzendler;Narayanan Kasthuri;Wen-Biao Gan

  • Stably maintained dendritic spines are associated with lifelong memories

    Guang Yang;Feng Pan;Wen-Biao Gan

  • An optimized fluorescent probe for visualizing glutamate neurotransmission

    Jonathan S. Marvin;Bart G. Borghuis;Bart G. Borghuis;Lin Tian;Lin Tian;Joseph Cichon

  • Development of Long-Term Dendritic Spine Stability in Diverse Regions of Cerebral Cortex

    Yi Zuo;Aerie Lin;Paul Chang;Wen-Biao Gan

  • Sleep promotes branch-specific formation of dendritic spines after learning

    Guang Yang;Cora Sau Wan Lai;Joseph Cichon;Lei Ma

  • Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.

    Julia Tsai;Jaime Grutzendler;Jaime Grutzendler;Karen Duff;Wen-Biao Gan

  • Branch-specific dendritic Ca2+ spikes cause persistent synaptic plasticity

    Joseph Cichon;Wen-Biao Gan

  • Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex

    Yi Zuo;Guang Yang;Elaine Kwon;Wen-Biao Gan

  • REM sleep selectively prunes and maintains new synapses in development and learning

    Wei Li;Lei Ma;Lei Ma;Guang Yang;Wen-Biao Gan;Wen-Biao Gan

  • Thinned-skull cranial window technique for long-term imaging of the cortex in live mice.

    Guang Yang;Feng Pan;Christopher N Parkhurst;Jaime Grutzendler

  • Choice of cranial window type for in vivo imaging affects dendritic spine turnover in the cortex.

    Hua-Tai Xu;Feng Pan;Guang Yang;Wen-Biao Gan

  • Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration.

    Lian Zhao;Matthew K Zabel;Xu Wang;Wenxin Ma

  • Dendritic Spine Dynamics

    D. Harshad Bhatt;Shengxiang Zhang;Wen-Biao Gan

  • Opposite effects of fear conditioning and extinction on dendritic spine remodelling

    Cora Sau Wan Lai;Thomas F. Franke;Wen-Biao Gan

  • Multicolor “DiOlistic” Labeling of the Nervous System Using Lipophilic Dye Combinations

    Wen Biao Gan;Jaime Grutzendler;Wai Thong Wong;Rachel O L Wong

  • Glucocorticoids are critical regulators of dendritic spine development and plasticity in vivo

    Conor Liston;Wen-Biao Gan

  • Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models

    Jordi Magrané;Czrina Cortez;Wen-Biao Gan;Giovanni Manfredi

  • Defective Neuromuscular Synapses in Mice Lacking Amyloid Precursor Protein (APP) and APP-Like Protein 2

    Pei Wang;Guang Yang;Dennis R. Mosier;Dennis R. Mosier;Paul Chang

Frequent Co-Authors

Jeff W. Lichtman
Jeff W. Lichtman Harvard University
Rachel O.L. Wong
Rachel O.L. Wong University of Washington
Richard I. Carp
Richard I. Carp New York State Office for People With Developmental Disabilities
Moses V. Chao
Moses V. Chao New York University
Conor Liston
Conor Liston Cornell University
Joshua R. Sanes
Joshua R. Sanes Harvard University
Thomas Misgeld
Thomas Misgeld Technical University of Munich
Hui Zheng
Hui Zheng Baylor College of Medicine
Zhigang He
Zhigang He Boston Children's Hospital

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