Hiroaki Kiyokawa

Overview

Best Publications

• Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27Kip1

  Hiroaki Kiyokawa;Rhonda D Kineman;Katia O Manova-Todorova;Vera C Soares

  1540
  Citations

• Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity.

  Tateki Tsutsui;Bahar Hesabi;David S. Moons;Pier Paolo Pandolfi

  513
  Citations

• Requirement for CDK4 kinase function in breast cancer

  Qunyan Yu;Ewa Sicinska;Yan Geng;Marie Ahnström

  503
  Citations

• Cdc2–cyclin E complexes regulate the G1/S phase transition

  Eiman Aleem;Hiroaki Kiyokawa;Philipp Kaldis

  475
  Citations

• The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

  C Missero;F Di Cunto;H Kiyokawa;A Koff

  387
  Citations

• The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration

  Xinhe Wang;Hiroaki Kiyokawa;Margaret B. Dennewitz;Robert H. Costa

  371
  Citations

• Formation of p27-CDK complexes during the human mitotic cell cycle

  Timothy J. Soos;Hiroaki Kiyokawa;Jie Shi Yan;Mark Stephen Rubin

  328
  Citations

• Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1.

  Patrizia Casaccia-Bonnefil;Ravi Tikoo;Hiroaki Kiyokawa;Victor Friedrich

  316
  Citations

• Rapamycin resistance tied to defective regulation of p27Kip1.

  Yan Luo;Steven O. Marx;Hiroaki Kiyokawa;Andrew Koff

  274
  Citations

• Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.

  Jennifer E. Skeen;Prashanth T. Bhaskar;Chia Chen Chen;William S. Chen

  267
  Citations

• Enhanced Ribosomal Association of p27Kip1 mRNA Is a Mechanism Contributing to Accumulation during Growth Arrest

  S. Sean Millard;Jie Shi Yan;Hoang Nguyen;Michele Pagano

  264
  Citations

• Akt Induces β-Cell Proliferation by Regulating Cyclin D1, Cyclin D2, and p21 Levels and Cyclin-Dependent Kinase-4 Activity

  Szabolcs Fatrai;Lynda Elghazi;Norman Balcazar;Corentin Cras-Méneur

  253
  Citations

• Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation

  Valentina Gandin;Annarita Miluzio;Anna Maria Barbieri;Anne Beugnet

  240
  Citations

• The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis.

  Katherine Krupczak-Hollis;Xinhe Wang;Xinhe Wang;Vladimir V. Kalinichenko;Vladimir V. Kalinichenko;Galina A. Gusarova

  236
  Citations

• Combined Loss of Cdk2 and Cdk4 Results in Embryonic Lethality and Rb Hypophosphorylation

  Cyril Berthet;Kimberly D. Klarmann;Mary Beth Hilton;Hyung Chan Suh

  211
  Citations

• Cdk4 promotes adipogenesis through PPARgamma activation.

  Anna Abella;Pierre Dubus;Marcos Malumbres;Sushil G. Rane

  193
  Citations

• Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence

  Xianghong Zou;Dipankar Ray;Aileen Aziyu;Konstantin Christov

  182
  Citations

• Loss of cyclin-dependent kinase inhibitors produces adipocyte hyperplasia and obesity

  Afia Naaz;Denise R. Holsberger;Gary A. Iwamoto;Amanda Nelson

  151
  Citations

• Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells.

  H Kiyokawa;V M Richon;R A Rifkind;P A Marks

  146
  Citations

• The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1.

  Xianghong Zou;Tateki Tsutsui;Dipankar Ray;James F. Blomquist

  144
  Citations