World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
59
Citations
9828
World Ranking
3268
National Ranking
1423

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Mary Ann Handel is affiliated with The Jackson Laboratory in the United States and is an active contributor to the field of Biochemistry, Genetics and Molecular Biology. Their work primarily spans molecular biology and genetics, with additional research intersecting ecology, evolution, and plant science.

The scientist's recent research output includes papers published in several notable journals. These publications are:

  • Regulation of meiotic progression by Sertoli-cell androgen signaling, 2020, Molecular Biology of the Cell
  • Age and Genetic Background Modify Hybrid Male Sterility in House Mice, 2020, Genetics
  • Sexual dimorphism in the meiotic requirement for PRDM9: A mammalian evolutionary safeguard, 2020, Science Advances
  • The XY body: an attractive chromatin domain, 2020, Biology of Reproduction
  • Reproductive genomics of the mouse: implications for human fertility and infertility, 2023, Development

Mary Ann Handel's research interests engage with several main topics within genetics and molecular biology:

  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Epigenetics and DNA Methylation
  • Genetic Mapping and Diversity in Plants and Animals
  • Animal Ecology and Behavior Studies
  • Animal Behavior and Reproduction

Frequent coauthors contributing to the scientist's publications include:

  • Beth L. Dumont
  • Natalie R. Powers
  • Catherine Brunton
  • Petko M. Petkov
  • Tanmoy Bhattacharyya

Their research has been published repeatedly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biology of Reproduction
  • Molecular Biology of the Cell
  • Genetics
  • Science Advances

Mary Ann Handel was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2009.

Best Publications

  • Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog.

    Douglas L. Pittman;John Cobb;Kerry J. Schimenti;Lawriston A. Wilson

  • Genetics of mammalian meiosis: regulation, dynamics and impact on fertility

    Mary Ann Handel;John C. Schimenti

  • Sex chromosomes, recombination, and chromatin conformation

    Bruce D. McKee;Mary Ann Handel

  • The XY body: a specialized meiotic chromatin domain

    Mary Ann Handel

  • Ultra-High Resolution 3D Imaging of Whole Cells

    Fang Huang;Fang Huang;George Sirinakis;George Sirinakis;Edward S. Allgeyer;Edward S. Allgeyer;Lena K. Schroeder

  • BRCA2 deficiency in mice leads to meiotic impairment and infertility.

    Shyam K. Sharan;April Pyle;Vincenzo Coppola;Janice Babus

  • ASYMMETRY AND POLYMORPHISM OF HYBRID MALE STERILITY DURING THE EARLY STAGES OF SPECIATION IN HOUSE MICE

    Jeffrey M. Good;Mary Ann Handel;Michael W. Nachman

  • Evidence for meiotic spindle checkpoint from analysis of spermatocytes from Robertsonian-chromosome heterozygous mice.

    Shannon Eaker;April Pyle;John Cobb;Mary Ann Handel

  • Meiotic events at the centromeric heterochromatin: histone H3 phosphorylation, topoisomerase IIα localization and chromosome condensation

    John Cobb;Mitsuko Miyaike;Akihiko Kikuchi;Mary Ann Handel

  • The mouse meiotic mutation mei1 disrupts chromosome synapsis with sexually dimorphic consequences for meiotic progression.

    Brian J. Libby;Rabindranath De La Fuente;Marilyn J. O'Brien;Karen Wigglesworth

  • MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination

    Mengcheng Luo;Fang Yang;N. Adrian Leu;Jessica Landaiche

  • Imprinting of a RING Zinc-Finger Encoding Gene in the Mouse Chromosome Region Homologous to the Prader-Willi Syndrome Genetic Region

    Michelle T. C. Jong;Alisoun H. Carey;Kim A. Caldwell;Michel H. Lau

  • SUMO modified proteins localize to the XY body of pachytene spermatocytes.

    Richard S. Rogers;Richard S. Rogers;Amy Inselman;Amy Inselman;Mary Ann Handel;Michael J. Matunis

  • INDUCED PREMATURE G2/M-PHASE TRANSITION IN PACHYTENE SPERMATOCYTES INCLUDES EVENTS UNIQUE TO MEIOSIS

    Tim Wiltshire;Cynthia Park;Kim A. Caldwell;Mary Ann Handel

  • Tissue-Specific Functional Networks for Prioritizing Phenotype and Disease Genes

    Yuanfang Guan;Dmitriy Gorenshteyn;Margit Burmeister;Aaron K. Wong

  • New gene family defined by MORC, a nuclear protein required for mouse spermatogenesis.

    Norimitsu Inoue;Karl D. Hess;Randall W. Moreadith;Laura L. Richardson

  • Acquisition of Competence to Condense Metaphase I Chromosomes during Spermatogenesis

    John Cobb;Benjamin Cargile;Mary Ann Handel

  • A-MYB (MYBL1) transcription factor is a master regulator of male meiosis

    Ewelina Bolcun-Filas;Laura A. Bannister;Alex Barash;Kerry J. Schimenti

  • Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes

    Philip W Jordan;Jesse Karppinen;Mary Ann Handel

  • Protamine transcript sharing among postmeiotic spermatids.

    Kim A. Caldwell;Mary Ann Handel

Frequent Co-Authors

John C. Schimenti
John C. Schimenti Cornell University
John J. Eppig
John J. Eppig Jackson Laboratory
Kim A. Caldwell
Kim A. Caldwell University of Alabama
Tim Wiltshire
Tim Wiltshire University of North Carolina at Chapel Hill
Kenneth Paigen
Kenneth Paigen The Jackson Laboratory
Lisa Stubbs
Lisa Stubbs University of Illinois at Urbana-Champaign
Alberto M. Pendás
Alberto M. Pendás University of Salamanca
Muriel T. Davisson
Muriel T. Davisson University of California, Los Angeles
Norman B. Hecht
Norman B. Hecht University of Pennsylvania
Lino Tessarollo
Lino Tessarollo National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Genetics in the USA opens the door to a variety of career and educational pathways. For those interested in supporting healthcare operations, medical billing and coding classes are a practical choice. These courses provide essential skills to ensure accurate patient data management and insurance processing, making them ideal for those seeking flexible, entry-level roles within healthcare.

If a more patient-facing career appeals, consider exploring nursing colleges with high acceptance rates. Nursing offers a stable and rewarding path, and these programs can make it easier to begin your journey in the medical field.

For those with leadership ambitions, many universities offer online healthcare administration programs that equip graduates with skills in management, policy, and healthcare systems. These are excellent options for Genetics students wishing to move into organizational roles.

Additionally, there are healthcare administration degrees available online that are both flexible and affordable. These degrees are ideal for balancing work and study, and they provide a solid foundation for diverse careers within the healthcare sector.

Best Scientists Citing Mary Ann Handel

Trending Scientists