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Molecular Biology

D-Index
71
Citations
13524
World Ranking
1392
National Ranking
706

Overview

Norman B. Hecht was affiliated with the University of Pennsylvania in the United States. Their research contributions primarily focused on the field of medicine, with particular attention to neurology, pulmonary and respiratory medicine, and cancer research.

Their work covered several key topics, including:

  • Parkinson's Disease and Spinal Disorders
  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Cancer Genomics and Diagnostics
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment

Norman B. Hecht published in prominent scientific venues such as:

  • Brain and Spine
  • Molecular Oncology

Among their recent papers were:

  • "The impact of deep brain stimulation on back pain and adult spinal deformities associated with Parkinson's disease," published in 2024 in Brain and Spine
  • "Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing," published in 2025 in Molecular Oncology

Norman B. Hecht collaborated frequently with several co-authors, including:

  • Philipp Spindler
  • Yasmin Alzoobi
  • Seyran Bozkurt
  • Katharina Faust
  • Peter Vajkoczy

Best Publications

  • Haploinsufficiency of protamine-1 or -2 causes infertility in mice.

    Chunghee Cho;William D. Willis;Eugenia H. Goulding;Haesook Jung-Ha

  • Translational regulation and deadenylation of a protamine mRNA during spermiogenesis in the mouse

    Kenneth C. Kleene;Robert J. Distel;Norman B. Hecht

  • Protamine 2 Deficiency Leads to Sperm DNA Damage and Embryo Death in Mice

    Chunghee Cho;Haesook Jung-Ha;William D. Willis;Eugenia H. Goulding

  • MicroRNA Mirn122a Reduces Expression of the Posttranscriptionally Regulated Germ Cell Transition Protein 2 (Tnp2) Messenger RNA (mRNA) by mRNA Cleavage

    Zuoren Yu;Tobias Raabe;Norman B. Hecht

  • Mammalian Male and Female Germ Cells Express a Germ Cell-Specific Y-Box Protein, MSY2

    Wei Gu;Seshadri Tekur;Rolland Reinbold;John J. Eppig

  • Binding of a phosphoprotein to the 3' untranslated region of the mouse protamine 2 mRNA temporally represses its translation.

    Yunhee Kim Kwon;N. B. Hecht

  • Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility

    Juxiang Yang;Sergey Medvedev;Junying Yu;Linda C. Tang

  • Testis-specific cytochrome c-null mice produce functional sperm but undergo early testicular atrophy

    Sonoko Narisawa;Norman B. Hecht;Erwin Goldberg;Kelly M. Boatright

  • Maternal inheritance of the mouse mitochondrial genome is not mediated by a loss or gross alteration of the paternal mitochondrial DNA or by methylation of the oocyte mitochondrial DNA

    Norman B. Hecht;Hetty Liem;Kenneth C. Kleene;Robert J. Distel

  • Mouse protamine 2 is synthesized as a precursor whereas mouse protamine 1 is not.

    P C Yelick;R Balhorn;P A Johnson;M Corzett

  • Expression profiling reveals meiotic male germ cell mRNAs that are translationally up- and down-regulated

    Naoko Iguchi;John W. Tobias;Norman B. Hecht

  • Cytoplasmic protein binding to highly conserved sequences in the 3' untranslated region of mouse protamine 2 mRNA, a translationally regulated transcript of male germ cells.

    Yunhee K. Kwon;Norman B. Hecht

  • cDNA clones encoding cytoplasmic poly(A)+ RNAs which first appear at detectable levels in haploid phases of spermatogenesis in the mouse.

    Kenneth C. Kleene;Robert J. Distel;Norman B. Hecht

  • Nucleotide sequence of a cDNA clone encoding mouse protamine 1

    Kenneth C. Kleene;Robert J. Distel;Norman B. Hecht

  • The making of a spermatozoon: A molecular perspective

    Norman B. Hecht

  • Expression of MSY2 in mouse oocytes and preimplantation embryos.

    Junying Yu;Norman B. Hecht;Richard M. Schultz

  • Sequence homologies in the mouse protamine 1 and 2 genes.

    Paula A. Johnson;Jacques J. Peschon;Pamela C. Yelick;Richard D. Palmiter

  • Testis/brain RNA-binding protein attaches translationally repressed and transported mRNAs to microtubules

    Jian R. Han;Gary K. Yiu;Norman B. Hecht

  • Haploid accumulation and translational control of phosphoglycerate kinase-2 messenger RNA during mouse spermatogenesis.

    Bert Gold;Hirokazu Fujimoto;James M. Kramer;Robert P. Erickson

  • Mitochondrial gene expression in male germ cells of the mouse

    Acacia A. Alcivar;Laura E. Hake;Clarke F. Millette;Jacquetta M. Trasler

Frequent Co-Authors

Carlos R. Morales
Carlos R. Morales McGill University
Richard M. Schultz
Richard M. Schultz University of Pennsylvania
Martti Parvinen
Martti Parvinen University of Turku
Edward M. Eddy
Edward M. Eddy National Institutes of Health
Michael D. Griswold
Michael D. Griswold Washington State University
Christine A. Kozak
Christine A. Kozak National Institutes of Health
Joel M. Stein
Joel M. Stein University of Pennsylvania
Carl R. Woese
Carl R. Woese University of Illinois at Urbana-Champaign
Mary Ann Handel
Mary Ann Handel The Jackson Laboratory
Lee M. Silver
Lee M. Silver Princeton University

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