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D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
19656
World Ranking
5602
National Ranking
2660

Overview

Edward M. Eddy is affiliated with the National Institutes of Health in the United States. Their research primarily spans the field of medicine, with specific contributions to reproductive medicine, public health, environmental and occupational health, genetics, surgery, and molecular biology.

The scientist's work includes several published papers focused on reproductive biology and related topics. Notable publications include:

  • Actin-related protein ACTL7B ablation leads to OAT with multiple morphological abnormalities of the flagellum and male infertility in mice, 2023, Biology of Reproduction
  • Cleavage of Disulfide Bonds in Mouse Spermatogenic Cell-Specific Type 1 Hexokinase Isozyme Is Associated with Increased Hexokinase Activity and Initiation of Sperm Motility, 2020, UNC Libraries
  • Speriolin Is a Novel Spermatogenic Cell-specific Centrosomal Protein Associated with the Seventh WD Motif of Cdc20, 2021, UNC Libraries
  • Spermatogenic cell-specific type 1 hexokinase is the predominant hexokinase in sperm, 2020, UNC Libraries

The recurring research themes in Eddy's work include sperm and testicular function, reproductive biology and fertility, genetic and clinical aspects of sex determination and chromosomal abnormalities, pancreatic function and diabetes, and renal and related cancers.

Frequent co-authors collaborating with Edward M. Eddy encompass:

  • Noriko Nakamura
  • Chisato Mori
  • Tracy M. Clement
  • Christopher B. Geyer
  • William D. Willis

Their publications appear predominantly in venues such as UNC Libraries, which hosts the majority of their work, and Biology of Reproduction, reflecting a focus on reproductive research.

The scientist's multidisciplinary subfields of study highlight an overlap of reproductive medicine with public health and genetics. This suggests that their investigations consider both the biological mechanisms underpinning reproductive function and broader health-related implications.

Best Publications

  • Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility

    E. M. Eddy;Todd F. Washburn;Donna O. Bunch;Eugenia H. Goulding

  • Germ plasm and the differentiation of the germ cell line.

    Eddy Em

  • Fertilization Defects in Sperm from Mice Lacking Fertilin β

    Chunghee Cho;Donna O.Dell Bunch;Jean Emmanuel Faure;Eugenia H. Goulding

  • GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE-S, A SPERM-SPECIFIC GLYCOLYTIC ENZYME, IS REQUIRED FOR SPERM MOTILITY AND MALE FERTILITY

    Kiyoshi Miki;Weidong Qu;Weidong Qu;Eugenia H. Goulding;William D. Willis

  • Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility.

    David J. Dix;James W. Allen;Barbara W. Collins;Chisato Mori

  • Haploinsufficiency of protamine-1 or -2 causes infertility in mice.

    Chunghee Cho;William D. Willis;Eugenia H. Goulding;Haesook Jung-Ha

  • Male germ cell gene expression.

    Edward M Eddy

  • Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes.

    Korach Ks;Couse Jf;Curtis Sw;Washburn Tf

  • Fibrous sheath of mammalian spermatozoa.

    Edward M. Eddy;Kiyotaka Toshimori;Deborah A. O'Brien

  • Protamine 2 Deficiency Leads to Sperm DNA Damage and Embryo Death in Mice

    Chunghee Cho;Haesook Jung-Ha;William D. Willis;Eugenia H. Goulding

  • Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility.

    Kiyoshi Miki;William D. Willis;Paula R. Brown;Eugenia H. Goulding

  • Observations on the Fine Structure and Relationships of the Chromatoid Body in Mammalian Spermatogenesis

    Don W. Fawcett;Edward M. Eddy;David M. Phillips

  • Role of heat shock protein HSP70-2 in spermatogenesis.

    Edward M. Eddy

  • HSP70-2 is required for desynapsis of synaptonemal complexes during meiotic prophase in juvenile and adult mouse spermatocytes

    David J. Dix;James W. Allen;Barbara W. Collins;Patricia Poorman-Allen

  • Glycoconjugate expression during embryogenesis and its biological significance.

    Bruce A. Fenderson;E. M. Eddy;Sen‐Itiroh Hakomori

  • Expression of the Gene for Mouse Lactate Dehydrogenase C (Ldhc) Is Required for Male Fertility

    Fanny Odet;Chongwen Duan;William D. Willis;Eugenia H. Goulding

  • The acrosome reaction of Strongylocentrotus purpuratus sperm. Ion requirements and movements.

    Robert W. Schackmann;E.M. Eddy;Bennett M. Shapiro

  • HSP70-2 is required for CDC2 kinase activity in meiosis I of mouse spermatocytes.

    Dahai Zhu;David J. Dix;E. M. Eddy

  • Phosphoglycerate Kinase 2 (PGK2) Is Essential for Sperm Function and Male Fertility in Mice

    Polina V. Danshina;Christopher B. Geyer;Qunsheng Dai;Eugenia H. Goulding

  • Regulation of gene expression during spermatogenesis

    E.M Eddy

Frequent Co-Authors

Deborah A. O'Brien
Deborah A. O'Brien University of North Carolina at Chapel Hill
Kenneth S. Korach
Kenneth S. Korach National Institutes of Health
Bennett M. Shapiro
Bennett M. Shapiro VBL Therapeutics
Eun-Young Choi
Eun-Young Choi Vanderbilt University
Kiyotaka Toshimori
Kiyotaka Toshimori Chiba University
Lauriane Kuhn
Lauriane Kuhn Centre national de la recherche scientifique, CNRS
Norman B. Hecht
Norman B. Hecht University of Pennsylvania
Myriam Ferro
Myriam Ferro Grenoble Alpes University
Jérôme Garin
Jérôme Garin CEA Grenoble
Dennis B. Lubahn
Dennis B. Lubahn University of Missouri

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