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Molecular Biology

D-Index
51
Citations
14689
World Ranking
2475
National Ranking
1221

Overview

Kenneth Paigen is affiliated with The Jackson Laboratory in the United States. Their research spans primarily the field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology and Genetics as key subfields.

The scientist's contributions cover several main topics in biological research including:

  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • DNA Repair Mechanisms
  • Genetic Mapping and Diversity in Plants and Animals
  • CRISPR and Genetic Engineering
  • Chromosomal and Genetic Variations
  • Genomic variations and chromosomal abnormalities

Kenneth Paigen has published multiple academic articles over recent years, with selected papers including:

  • "HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hot spots" (2020), published in Genes & Development
  • "Sexual dimorphism in the meiotic requirement for PRDM9: A mammalian evolutionary safeguard" (2020), published in Science Advances
  • "Variation in histone configurations correlates with gene expression across nine inbred strains of mice" (2023), published in Genome Research
  • "Differential effects of two catalytic mutations on full-length PRDM9 and its isolated PR/SET domain reveal a case of pseudomodularity" (2021), published in Genetics
  • "Differential effects of two catalytic mutations on full-length PRDM9 and its isolated PR/SET domain reveal a case of pseudo-modularity" (2021), published in bioRxiv (Cold Spring Harbor Laboratory)

The frequent co-authors who collaborate with Kenneth Paigen include:

  • Petko M. Petkov
  • Catrina Spruce
  • Gregory W. Carter
  • Christopher L. Baker
  • Natalie R. Powers

Their publications have appeared in venues that are regularly consulted in their area of study, such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genes & Development
  • Science Advances
  • Genome Research
  • Genetics

Best Publications

  • The Collaborative Cross, a community resource for the genetic analysis of complex traits

    Gary A. Churchill;David C. Airey;Hooman Allayee;Joe M. Angel

  • Prdm9 controls activation of mammalian recombination hotspots.

    Emil D. Parvanov;Petko M. Petkov;Kenneth Paigen

  • Density alterations associated with transducing ability in the bacteriophage lambda

    J. Weigle;Matthew Meselson;Kenneth Paigen

  • A mouse phenome project.

    Kenneth Paigen;Janan T. Eppig

  • Mammalian recombination hot spots: properties, control and evolution

    Kenneth Paigen;Petko Petkov

  • Mammalian beta-glucuronidase: genetics, molecular biology, and cell biology.

    Kenneth Paigen

  • Genetic control of glucuronidase induction in mice.

    Richard T. Swank;Kenneth Paigen;Roger E. Ganschow

  • The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo.

    Natalie R. Powers;Emil D. Parvanov;Christopher L. Baker;Michael Walker

  • Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

    Alison H. Harrill;Paul B. Watkins;Stephen Su;Pamela K. Ross

  • Questionable Relation of Aryl Hydrocarbon Hydroxylase to Lung-Cancer Risk

    Beverly Paigen;Hira L. Gurtoo;Jun Minowada;Lorne Houten

  • The recombinational anatomy of a mouse chromosome.

    Kenneth Paigen;Jin P. Szatkiewicz;Kathryn Sawyer;Nicole Leahy

  • Biochemical and genetic evidence for a macromolecular -glucuronidase complex in microsomal membranes.

    Richard T. Swank;Kenneth Paigen

  • The molecular genetics of mammalian glucuronidase.

    Kenneth Paigen;Richard T. Swank;Shiro Tomino;Roger E. Ganschow

  • Crossover interference in the mouse.

    Karl W Broman;Lucy B Rowe;Gary A Churchill;Ken Paigen

  • PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration

    Christopher L. Baker;Michael Walker;Shimpei Kajita;Petko M. Petkov

  • Evidence of a large-scale functional organization of Mammalian chromosomes.

    Petko M Petkov;Joel H Graber;Gary A Churchill;Keith DiPetrillo

  • PRDM9 drives evolutionary erosion of hotspots in Mus musculus through haplotype-specific initiation of meiotic recombination.

    Christopher L. Baker;Shimpei Kajita;Michael Walker;Ruth L. Saxl

  • PRDM9 and Its Role in Genetic Recombination

    Kenneth Paigen;Petko M. Petkov

  • Genetic regulation of mammalian glucuronidase.

    R T Swank;K Paigen;R Davey;Chapman

  • Crossover interference underlies sex differences in recombination rates.

    Petko M. Petkov;Karl W. Broman;Jin P. Szatkiewicz;Kenneth Paigen

Frequent Co-Authors

David W. Threadgill
David W. Threadgill Texas A&M University
Gary A. Churchill
Gary A. Churchill The Jackson Laboratory
Daniel Pomp
Daniel Pomp University of North Carolina at Chapel Hill
Kent W. Hunter
Kent W. Hunter National Institutes of Health
Fernando Pardo-Manuel de Villena
Fernando Pardo-Manuel de Villena University of North Carolina at Chapel Hill
Elissa J. Chesler
Elissa J. Chesler University of Tennessee at Knoxville
George M. Weinstock
George M. Weinstock The Jackson Laboratory
Beverly Paigen
Beverly Paigen University of Pennsylvania
Patrick F. Sullivan
Patrick F. Sullivan University of North Carolina at Chapel Hill
Deborah A. O'Brien
Deborah A. O'Brien University of North Carolina at Chapel Hill

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