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Biology and Biochemistry

D-Index
51
Citations
10102
World Ranking
17116
National Ranking
7053

Overview

Jeffrey A. Nickerson is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research spans multiple fields within biological and medical sciences, with a focus on biochemistry, genetics, molecular biology, and medicine.

The main fields of study associated with Nickerson's work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, subfields of focus are:

  • Molecular Biology
  • Neurology
  • Genetics
  • Immunology
  • Pulmonary and Respiratory Medicine

Nickerson's research covers a range of topics, especially related to RNA and cellular mechanisms. Key topics include:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • Nuclear Structure and Function
  • Neurogenetic and Muscular Disorders Research
  • Immune cells in cancer
  • Epigenetics and DNA Methylation
  • Ferroptosis and cancer prognosis

Some of their recent published papers are:

  • Long non-coding RNAs: roles in cellular stress responses and epigenetic mechanisms regulating chromatin, 2024, Nucleus
  • Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia, 2024, Nature Communications
  • SP140 inhibits STAT1 signaling, induces IFN-γ in tumor-associated macrophages, and is a predictive biomarker of immunotherapy response, 2022, Journal for ImmunoTherapy of Cancer
  • The ribonucleoprotein network of the nucleus: a historical perspective, 2022, Current Opinion in Genetics & Development
  • Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway, 2021, Nature Neuroscience

Frequently publishing in distinguished journals, Nickerson contributes to venues such as:

  • Nature Neuroscience
  • Journal for ImmunoTherapy of Cancer
  • Nucleus
  • Nature Communications
  • Current Opinion in Genetics & Development

The scientist has collaborated repeatedly with several co-authors, indicating established research partnerships. Frequent collaborators include:

  • Daryl A. Bosco
  • Justin A. McDonough
  • William C. Skarnes
  • John E. Landers
  • Fatemeh Momen-Heravi

Nickerson's work is situated at the interface of molecular biology and medical research, contributing to understanding complex cellular processes, especially those involving RNA and nuclear function, with relevance to neurological diseases and cancer biology.

Best Publications

  • Nuclear structure in cancer cells.

    Daniele Zink;Andrew H. Fischer;Jeffrey A. Nickerson

  • Experimental observations of a nuclear matrix

    Jeffrey A. Nickerson

  • The Retinoblastoma Gene Product is a Cell Cycle-Dependent, Nuclear Matrix- Associated Protein

    Michael A. Mancini;Bei Shan;Jeffrey A. Nickerson;Sheldon Penman

  • Association of nuclear matrix antigens with exon-containing splicing complexes.

    B J Blencowe;J A Nickerson;R Issner;S Penman

  • Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus

    Sophie A. Lelièvre;Valerie M. Weaver;Jeffrey A. Nickerson;Carolyn A. Larabell

  • A COACTIVATOR OF PRE-MRNA SPLICING

    Benjamin J. Blencowe;Robbyn Issner;Jeffrey A. Nickerson;Phillip A. Sharp

  • Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2

    Daniel W. Young;Mohammad Q. Hassan;Jitesh Pratap;Mario Galindo;Mario Galindo

  • Chromatin architecture and nuclear RNA.

    Jeffrey A. Nickerson;Gabriela Krochmalnic;Katherine M. Wan;Sheldon Penman

  • The Nuclear Matrix: Past and Present

    Sheldon Penman;Benjamin J. Blencowe;Jeffrey A. Nickerson

  • The nuclear matrix protein NMP-1 is the transcription factor YY1

    B Guo;P R Odgren;A J van Wijnen

  • Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains

    Congmei Zeng;Sandra Marie McNeil;Shirwin M. Pockwinse;Jeffrey A. Nickerson

  • Pulse energy dependence of subcellular dissection by femtosecond laser pulses.

    A. Heisterkamp;I. Z. Maxwell;E. Mazur;Jean M. Underwood

  • The nuclear matrix revealed by eluting chromatin from a cross-linked nucleus

    Jeffrey A. Nickerson;Gabriela Krockmalnic;Katherine M. Wan;Sheldon Penman

  • Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS

    Helene Tran;Sandra Almeida;Jill Moore;Tania F. Gendron

  • The architectural organization of nuclear metabolism

    Jeffrey A. Nickerson;Benjamin J. Blencowe;Sheldon Penman

  • Modulation of Nuclear Shape by Substrate Rigidity

    David B. Lovett;Nandini Shekhar;Jeffrey A. Nickerson;Kyle J. Roux

  • The acute myeloid leukemia-associated protein, DEK, forms a splicing-dependent interaction with exon-product complexes.

    Tim McGarvey;Emanuel Rosonina;Susan McCracken;Qiyu Li

  • Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics

    Desiree M. Baron;Laura J. Kaushansky;Catherine L. Ward;Reddy Ranjith Kumar Sama

  • The SRm160/300 splicing coactivator subunits.

    Benjamin J. Blencowe;Göran Baurén;Adam G. Eldridge;Robbyn Issner

  • Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture.

    Karen M Imbalzano;Iva Tatarkova;Anthony N Imbalzano;Jeffrey A Nickerson

Frequent Co-Authors

Anthony N. Imbalzano
Anthony N. Imbalzano University of Massachusetts Chan Medical School
Gary S. Stein
Gary S. Stein University of Vermont
Janet L. Stein
Janet L. Stein University of Vermont
Jane B. Lian
Jane B. Lian University of Vermont
Sayyed K. Zaidi
Sayyed K. Zaidi University of Vermont
Andre J. Van Wijnen
Andre J. Van Wijnen University of Connecticut Health Center
Benjamin J. Blencowe
Benjamin J. Blencowe University of Toronto
Martin Montecino
Martin Montecino Andrés Bello University
Amjad Javed
Amjad Javed University of Alabama at Birmingham

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