Rohit Ramachandran

Overview

Best Publications

• Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing: A Case Study

  Spencer D. Schaber;Dimitrios I. Gerogiorgis;Rohit Ramachandran;James M. B. Evans

  572
  Citations

• Digital twins in pharmaceutical and biopharmaceutical manufacturing: A literature review

  Yingjie Chen;Ou Yang;Chaitanya Sampat;Pooja Bhalode

  232
  Citations

• An integrated approach for dynamic flowsheet modeling and sensitivity analysis of a continuous tablet manufacturing process

  Fani Boukouvala;Vasilios Niotis;Rohit Ramachandran;Fernando J. Muzzio

  208
  Citations

• An engineering study on the enhanced control and operation of continuous manufacturing of pharmaceutical tablets via roller compaction.

  Ravendra Singh;Marianthi Ierapetritou;Rohit Ramachandran

  153
  Citations

• System-wide hybrid MPC-PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction.

  Ravendra Singh;Marianthi Ierapetritou;Rohit Ramachandran

  133
  Citations

• A systematic framework for onsite design and implementation of a control system in a continuous tablet manufacturing process

  Ravendra Singh;Abhishek Sahay;Fernando J. Muzzio;Marianthi G. Ierapetritou

  115
  Citations

• Implementation of an advanced hybrid MPC-PID control system using PAT tools into a direct compaction continuous pharmaceutical tablet manufacturing pilot plant.

  Ravendra Singh;Abhishek Sahay;Krizia M. Karry;Fernando Muzzio

  113
  Citations

• Effective parameter estimation within a multi-dimensional population balance model framework

  Rohit Ramachandran;Paul I. Barton

  111
  Citations

• A mechanistic model for breakage in population balances of granulation: Theoretical kernel development and experimental validation

  Rohit Ramachandran;Charles D. Immanuel;Frantisek Stepanek;James D. Litster

  108
  Citations

• Experimental studies on distributions of granule size, binder content and porosity in batch drum granulation: Inferences on process modelling requirements and process sensitivities

  Rohit Ramachandran;Jonathan M.H. Poon;Constantijn F.W. Sanders;Thomas Glaser;Thomas Glaser

  106
  Citations

• Multi-dimensional population balance model development and validation for a twin screw granulation process

  Dana Barrasso;Arwa El Hagrasy;James D. Litster;Rohit Ramachandran

  100
  Citations

• Multi-scale modeling of granulation processes: Bi-directional coupling of PBM with DEM via collision frequencies

  Dana Barrasso;Rohit Ramachandran

  100
  Citations

• A multi-scale, mechanistic model of a wet granulation process using a novel bi-directional PBM–DEM coupling algorithm

  Dana Barrasso;Thomas Eppinger;Frances E. Pereira;Ravindra Aglave

  100
  Citations

• A Multi-Scale Hybrid CFD-DEM-PBM Description of a Fluid-Bed Granulation Process

  Maitraye Sen;Dana Barrasso;Ravendra Singh;Rohit Ramachandran

  94
  Citations

• A comparison of model order reduction techniques for a four-dimensional population balance model describing multi-component wet granulation processes

  Dana Barrasso;Rohit Ramachandran

  89
  Citations

• A multi-dimensional population balance model approach to continuous powder mixing processes

  Maitraye Sen;Rohit Ramachandran

  87
  Citations

• Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation

  Jonathan M.-H. Poon;Rohit Ramachandran;Constantijn F. W. Sanders;Thomas Glaser;Thomas Glaser

  84
  Citations

• Computer-Aided Flowsheet Simulation of a Pharmaceutical Tablet Manufacturing Process Incorporating Wet Granulation

  Fani Boukouvala;Anwesha Chaudhury;Maitraye Sen;Ruijie Zhou

  83
  Citations

• A reduced order PBM–ANN model of a multi-scale PBM–DEM description of a wet granulation process

  Dana Barrasso;Ashutosh Tamrakar;Rohit Ramachandran

  83
  Citations

• Real time monitoring of powder blend bulk density for coupled feed-forward/feed-back control of a continuous direct compaction tablet manufacturing process.

  Ravendra Singh;Andrés D. Román-Ospino;Rodolfo J. Romañach;Marianthi Ierapetritou

  82
  Citations