His main research concerns Granulation, Pharmaceutical manufacturing, Control engineering, Process engineering and Critical quality attributes. Rohit Ramachandran combines subjects such as Porosity, Material properties, Particle-size distribution, Particle size and Mechanics with his study of Granulation. As a part of the same scientific study, Rohit Ramachandran usually deals with the Particle size, concentrating on Simulation and frequently concerns with Discrete element method and Design process.
Rohit Ramachandran connects Pharmaceutical manufacturing with Process in his study. His studies examine the connections between Control engineering and genetics, as well as such issues in Control system, with regards to Quality by Design, PID controller and Model predictive control. His Process engineering research integrates issues from Scale, Batch production and Sensitivity.
Granulation, Process engineering, Pharmaceutical manufacturing, Critical quality attributes and Discrete element method are his primary areas of study. The study incorporates disciplines such as Porosity and Particle-size distribution, Chemical engineering, Particle size in addition to Granulation. He studied Process engineering and Compaction that intersect with Factorial experiment.
Among his Pharmaceutical manufacturing studies, there is a synthesis of other scientific areas such as Quality by Design, Control engineering, Control system, Control theory and Batch processing. His PID controller study, which is part of a larger body of work in Control engineering, is frequently linked to Process control, bridging the gap between disciplines. Rohit Ramachandran works mostly in the field of Discrete element method, limiting it down to topics relating to Simulation and, in certain cases, Mixing.
The scientist’s investigation covers issues in Granulation, Process engineering, Discrete element method, Critical quality attributes and Process modeling. His work deals with themes such as Fluidized bed, Porosity and Capillary action, which intersect with Granulation. His Porosity study combines topics in areas such as Particle-size distribution and Particle size.
He has researched Process engineering in several fields, including Process design and Unit operation. His Discrete element method research integrates issues from Surrogate model, Shear and Computational science. His Critical quality attributes research is multidisciplinary, incorporating perspectives in Control system, Process analytical technology, Factorial experiment and Quality assurance.
His main research concerns Critical quality attributes, Granulation, Process engineering, Pharmaceutical manufacturing and Fluidized bed. His research investigates the connection between Critical quality attributes and topics such as Factorial experiment that intersect with issues in Compaction, Impeller, Particle-size distribution and Process modeling. His work carried out in the field of Granulation brings together such families of science as Process design and Particle size.
His work deals with themes such as Quality by Design and Computational fluid dynamics, which intersect with Process design. His Fluidized bed research includes elements of Dynamic simulation, Process and Sensitivity. The study incorporates disciplines such as Control system, Control theory, Control theory, Feed forward and Quality assurance in addition to Process analytical technology.
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Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing: A Case Study
Spencer D. Schaber;Dimitrios I. Gerogiorgis;Rohit Ramachandran;James M. B. Evans.
Industrial & Engineering Chemistry Research (2011)
An integrated approach for dynamic flowsheet modeling and sensitivity analysis of a continuous tablet manufacturing process
Fani Boukouvala;Vasilios Niotis;Rohit Ramachandran;Fernando J. Muzzio.
Computers & Chemical Engineering (2012)
An engineering study on the enhanced control and operation of continuous manufacturing of pharmaceutical tablets via roller compaction.
Ravendra Singh;Marianthi Ierapetritou;Rohit Ramachandran.
International Journal of Pharmaceutics (2012)
System-wide hybrid MPC-PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction.
Ravendra Singh;Marianthi Ierapetritou;Rohit Ramachandran.
European Journal of Pharmaceutics and Biopharmaceutics (2013)
A mechanistic model for breakage in population balances of granulation: Theoretical kernel development and experimental validation
Rohit Ramachandran;Charles D. Immanuel;Frantisek Stepanek;James D. Litster.
Chemical Engineering Research & Design (2009)
Effective parameter estimation within a multi-dimensional population balance model framework
Rohit Ramachandran;Paul I. Barton.
Chemical Engineering Science (2010)
A systematic framework for onsite design and implementation of a control system in a continuous tablet manufacturing process
Ravendra Singh;Abhishek Sahay;Fernando J. Muzzio;Marianthi G. Ierapetritou.
Computers & Chemical Engineering (2014)
Experimental studies on distributions of granule size, binder content and porosity in batch drum granulation: Inferences on process modelling requirements and process sensitivities
Rohit Ramachandran;Jonathan M.H. Poon;Constantijn F.W. Sanders;Thomas Glaser;Thomas Glaser.
Powder Technology (2008)
Implementation of an advanced hybrid MPC-PID control system using PAT tools into a direct compaction continuous pharmaceutical tablet manufacturing pilot plant.
Ravendra Singh;Abhishek Sahay;Krizia M. Karry;Fernando Muzzio.
International Journal of Pharmaceutics (2014)
Experimental validation studies on a multi-dimensional and multi-scale population balance model of batch granulation
Jonathan M.-H. Poon;Rohit Ramachandran;Constantijn F. W. Sanders;Thomas Glaser;Thomas Glaser.
Chemical Engineering Science (2009)
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