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Materials Science

D-Index
62
Citations
11958
World Ranking
6575
National Ranking
381

Overview

Peter Kleinebudde is affiliated with Heinrich Heine University Düsseldorf in Germany and has a significant body of research predominantly in engineering and pharmacology-related fields. Their work encompasses multiple disciplines related to pharmaceutical sciences and mechanical engineering.

Their primary fields of study include:

  • Engineering
  • Pharmacology, Toxicology and Pharmaceutics

More specialized subfields reflect a cross-disciplinary approach integrating:

  • Mechanical Engineering
  • Pharmaceutical Science
  • Analytical Chemistry
  • Materials Chemistry
  • Molecular Biology

Key research topics covered in their publications involve:

  • Drug Solubility and Delivery Systems
  • Powder Metallurgy Techniques and Materials
  • Mineral Processing and Grinding
  • Injection Molding Process and Properties
  • Protein purification and stability
  • Granular flow and fluidized beds
  • Spectroscopy and Chemometric Analyses

Peter Kleinebudde has contributed substantially to several scientific journals, with frequent publications in:

  • International Journal of Pharmaceutics
  • European Journal of Pharmaceutics and Biopharmaceutics
  • Pharmaceutics
  • International Journal of Pharmaceutics X
  • Pharmaceutical Development and Technology

Their recent papers exemplify their areas of focus and include:

  • Model predictive control in pharmaceutical continuous manufacturing: A review from a user's perspective (2021) in European Journal of Pharmaceutics and Biopharmaceutics
  • Tableting of mini-tablets in comparison with conventionally sized tablets: A comparison of tableting properties and tablet dimensions (2020) in International Journal of Pharmaceutics X
  • A review of regime maps for granulation (2020) in International Journal of Pharmaceutics
  • The relevance of granule fragmentation on reduced tabletability of granules from ductile or brittle materials produced by roll compaction/dry granulation (2020) in International Journal of Pharmaceutics
  • From powder to tablets: Investigation of residence time distributions in a continuous manufacturing process train as basis for continuous process verification (2020) in European Journal of Pharmaceutics and Biopharmaceutics

Kleinebudde collaborates frequently with a core group of co-authors, including:

  • Stefan Klinken
  • Robin Meier
  • Markus Krumme
  • Sabrina Berkenkemper
  • Sebastian Bollmann

Best Publications

  • Production of pellets via extrusion-spheronisation without the incorporation of microcrystalline cellulose: a critical review.

    Aleksandra Dukic-Ott;M Thommes;Jean Paul Remon;Peter Kleinebudde

  • Roll compaction/dry granulation: effect of raw material particle size on granule and tablet properties.

    Michael G. Herting;Peter Kleinebudde

  • Analysis of sustained-release tablet film coats using terahertz pulsed imaging.

    L. Ho;L. Ho;L. Ho;R. Müller;M. Römer;K.C. Gordon

  • A new multiparticulate delayed release system.: Part I: Dissolution properties and release mechanism

    Peter Schultz;Peter Kleinebudde

  • Impact of screw elements on continuous granulation with a twin-screw extruder.

    Dejan Djuric;Peter Kleinebudde

  • Oromucosal film preparations: classification and characterization methods

    Maren Preis;Christina Woertz;Peter Kleinebudde;Jörg Breitkreutz

  • Assessment of test methods evaluating mucoadhesive polymers and dosage forms: an overview.

    Christina Woertz;Maren Preis;Jörg Breitkreutz;Peter Kleinebudde

  • Shrinking and swelling properties of pellets containing microcrystalline cellulose and low substituted hydroxypropylcellulose: I. Shrinking properties

    Peter Kleinebudde

  • Non-destructive quantification of pharmaceutical tablet coatings using terahertz pulsed imaging and optical coherence tomography

    Shuncong Zhong;Yao-Chun Shen;Louise Ho;Louise Ho;Robert K. May

  • The crystallite-gel-model for microcrystalline cellulose in wet-granulation, extrusion, and spheronization.

    Peter Kleinebudde

  • A critical review on tablet disintegration

    Julian Quodbach;Peter Kleinebudde

  • Mechanism of drug release from polymethacrylate-based extrudates and milled strands prepared by hot-melt extrusion.

    Jessica Albers;Rainer Alles;Karin Matthée;Klaus Knop

  • Studies on the reduction of tensile strength of tablets after roll compaction/dry granulation

    Michael G Herting;Peter Kleinebudde

  • Preparation and characterization of spray-dried co-amorphous drug-amino acid salts.

    Katrine Tarp Jensen;Lasse Ingerslev Blaabjerg;Elisabeth Lenz;Adam Bohr

  • PAT-tools for process control in pharmaceutical film coating applications.

    Klaus Knop;Peter Kleinebudde

  • Mini review: Mechanisms to the loss of tabletability by dry granulation

    Changquan Calvin Sun;Peter Kleinebudde

  • Preliminary assessment of carrageenan as excipient for extrusion/spheronisation.

    Martin Bornhöft;Markus Thommes;Peter Kleinebudde

  • Use of kappa-carrageenan as alternative pelletisation aid to microcrystalline cellulose in extrusion/spheronisation. I. Influence of type and fraction of filler.

    Markus Thommes;Peter Kleinebudde

  • Applications of terahertz pulsed imaging to sustained-release tablet film coating quality assessment and dissolution performance.

    Louise Ho;Ronny Müller;Ronny Müller;Keith C. Gordon;Keith C. Gordon;Peter Kleinebudde;Peter Kleinebudde

  • Application of mixtures of polymeric carriers for dissolution enhancement of oxeglitazar using hot-melt extrusion.

    Adela Kalivoda;Matthias Fischbach;Peter Kleinebudde

  • Solid lipid extrusion of sustained release dosage forms.

    Claudia Reitz;Peter Kleinebudde

Frequent Co-Authors

Clare J. Strachan
Clare J. Strachan University of Helsinki
Johannes Khinast
Johannes Khinast Graz University of Technology
Michael Pepper
Michael Pepper University College London
Thomas Rades
Thomas Rades University of Copenhagen
J. Axel Zeitler
J. Axel Zeitler University of Cambridge
Keith C. Gordon
Keith C. Gordon University of Otago
Heike P. Schuchmann
Heike P. Schuchmann Karlsruhe Institute of Technology
Reinhard H.H. Neubert
Reinhard H.H. Neubert Martin Luther University Halle-Wittenberg
Gavin P. Reynolds
Gavin P. Reynolds Sheffield Hallam University
Andrea Gazzaniga
Andrea Gazzaniga University of Milan

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