D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 44 Citations 10,127 90 World Ranking 16082 National Ranking 6675

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Gene expression

The scientist’s investigation covers issues in Osteoblast, Endocrinology, Internal medicine, Cellular differentiation and Cell biology. His Osteoblast study combines topics in areas such as Osteocalcin, Gene expression and GPNMB. His work is dedicated to discovering how Gene expression, Bone cell are connected with Osteopontin and other disciplines.

His Endocrinology research is multidisciplinary, incorporating perspectives in Agonist and Bone healing. His study in Cell biology focuses on Extracellular matrix and Mesenchymal stem cell. His Extracellular matrix research is multidisciplinary, incorporating elements of Cell growth and Calvaria.

His most cited work include:

  • Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix (1407 citations)
  • Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation. (812 citations)
  • Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells. (481 citations)

What are the main themes of his work throughout his whole career to date?

Thomas A. Owen mostly deals with Molecular biology, Osteoblast, Cell biology, Endocrinology and Internal medicine. His studies in Molecular biology integrate themes in fields like Cellular differentiation, Complementary DNA, Northern blot, Regulation of gene expression and Response element. His Osteoblast research incorporates themes from Bone cell, Phenotype, Gene expression, Gene and Osteocalcin.

Thomas A. Owen combines subjects such as Bone formation, Growth factor and Cell growth with his study of Cell biology. Thomas A. Owen has included themes like Agonist, Receptor, Chondrocyte and CTGF in his Endocrinology study. His work in the fields of Estrogen, Bone remodeling and Hormone overlaps with other areas such as Matrix gla protein.

He most often published in these fields:

  • Molecular biology (43.33%)
  • Osteoblast (37.78%)
  • Cell biology (33.33%)

What were the highlights of his more recent work (between 2007-2020)?

  • Osteoblast (37.78%)
  • Receptor (10.00%)
  • Cell biology (33.33%)

In recent papers he was focusing on the following fields of study:

Osteoblast, Receptor, Cell biology, Agonist and Molecular biology are his primary areas of study. Thomas A. Owen merges many fields, such as Osteoblast and Hormone response element, in his writings. His Receptor study incorporates themes from Osteocalcin, Endocrinology, Transcription and Vitamin D Response Element.

Thomas A. Owen works in the field of Cell biology, focusing on Bone cell in particular. His research in Agonist intersects with topics in Prostaglandin E2 and Bone healing. His Molecular biology research includes themes of SMAD binding, SMAD, Immediate early protein, Proto-oncogene tyrosine-protein kinase Src and Response element.

Between 2007 and 2020, his most popular works were:

  • Osteoactivin, an anabolic factor that regulates osteoblast differentiation and function. (94 citations)
  • The role of connective tissue growth factor (CTGF/CCN2) in skeletogenesis. (62 citations)
  • 1α,25‐Dihydroxyvitamin D3 rapidly increases cytosolic calcium in clonal rat osteosarcoma cells lacking the vitamin D Receptor (60 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Amino acid

Thomas A. Owen mainly investigates CTGF, Endocrinology, Cell biology, Osteoblast and Internal medicine. The CTGF study combines topics in areas such as Molecular biology, Signal transduction, SMAD, Src family kinase and Response element. His work deals with themes such as Osteocalcin, Receptor and Calcium metabolism, Calcium, which intersect with Endocrinology.

His work carried out in the field of Cell biology brings together such families of science as Biochemistry and Glycoprotein. His study in Osteoblast is interdisciplinary in nature, drawing from both Chondrogenesis, Bone cell, GPNMB, Western blot and Retinoic acid. His biological study spans a wide range of topics, including VDRE and Chondrocyte.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Progressive development of the rat osteoblast phenotype in vitro: Reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix

Thomas A. Owen;Michael A. Aronow;Victoria Shalhoub;Leesa M. Barone.
Journal of Cellular Physiology (1990)

2317 Citations

Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation.

Gary S. Stein;Jane B. Lian;Thomas A. Owen.
The FASEB Journal (1990)

1329 Citations

Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells.

Michael A. Aronow;Louis C. Gerstenfeld;Thomas A. Owen;Melissa S. Tassinari.
Journal of Cellular Physiology (1990)

659 Citations

Pleiotropic Effects of Vitamin D on Osteoblast Gene Expression Are Related to the Proliferative and Differentiated State of the Bone Cell Phenotype: Dependency upon Basal Levels of Gene Expression, Duration of Exposure, and Bone Matrix Competency in Normal Rat Osteoblast Cultures

Thomas A. Owen;Michael S. Aronow;Leesa M. Barone;Brian Bettencourt.
Endocrinology (1991)

496 Citations

CLONING AND CHARACTERIZATION OF A NOVEL MEMBER OF THE TRANSFORMING GROWTH FACTOR-BETA /BONE MORPHOGENETIC PROTEIN FAMILY

Vishwas M. Paralkar;Amy L. Vail;William A. Grasser;Thomas A. Brown.
Journal of Biological Chemistry (1998)

397 Citations

Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: model for phenotype suppression of transcription

T A Owen;R Bortell;S A Yocum;S L Smock.
Proceedings of the National Academy of Sciences of the United States of America (1990)

292 Citations

Expression of connective tissue growth factor in bone: its role in osteoblast proliferation and differentiation in vitro and bone formation in vivo

Fayez F. Safadi;Jie Xu;Steven L. Smock;Reem A. Kanaan.
Journal of Cellular Physiology (2003)

245 Citations

An EP2 receptor-selective prostaglandin E2 agonist induces bone healing

V.M. Paralkar;Fran Borovečki;H.Z. Ke;K.O. Cameron.
Proceedings of the National Academy of Sciences of the United States of America (2003)

228 Citations

Effects of CP-336,156, a new, nonsteroidal estrogen agonist/antagonist, on bone, serum cholesterol, uterus and body composition in rat models.

Hua Zhu Ke;Vishwas M. Paralkar;William A. Grasser;D. Todd Crawford.
Endocrinology (1998)

206 Citations

Expression of heat shock genes during differentiation of mammalian osteoblasts and promyelocytic leukemia cells.

Abdul Rauf Shakoori;Annette M. Oberdorf;Thomas A. Owen;Lee A. Weber.
Journal of Cellular Biochemistry (1992)

178 Citations

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